ID   BIOD_CHRSD              Reviewed;         237 AA.
AC   Q1QYD9;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2006, sequence version 1.
DT   16-JUN-2009, entry version 20.
DE   RecName: Full=Dethiobiotin synthetase;
DE            EC=6.3.3.3;
DE   AltName: Full=Dethiobiotin synthase;
DE   AltName: Full=DTB synthetase;
DE            Short=DTBS;
GN   Name=bioD; OrderedLocusNames=Csal_1163;
OS   Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB
OS   13768).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Oceanospirillales;
OC   Halomonadaceae; Chromohalobacter.
OX   NCBI_TaxID=290398;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T.,
RA   Bruce D., Han C., Tapia R., Gilna P., Saunders E., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Csonka L.N.,
RA   O'Conner K., Vreeland R.H., Oren A., Vargas C., Nieto J., Arahal D.R.,
RA   Goodner B., Wheeler C., Hall P., Ewing A., Benson L., McBeath D.,
RA   Canovas D., Richardson P.;
RT   "Complete sequence of Chromohalobacter salexigens DSM 3043.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: ATP + 7,8-diaminononanoate + CO(2) = ADP +
CC       phosphate + dethiobiotin.
CC   -!- COFACTOR: Magnesium (By similarity).
CC   -!- PATHWAY: Cofactor biosynthesis; biotin biosynthesis; biotin from
CC       6-carboxyhexanoyl-CoA: step 3/4.
CC   -!- SIMILARITY: Belongs to the dethiobiotin synthetase family.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000285; ABE58519.1; -; Genomic_DNA.
DR   RefSeq; YP_573218.1; -.
DR   GeneID; 4028102; -.
DR   GenomeReviews; CP000285_GR; Csal_1163.
DR   KEGG; csa:Csal_1163; -.
DR   NMPDR; fig|290398.4.peg.1186; -.
DR   HOGENOM; Q1QYD9; -.
DR   OMA; Q1QYD9; CLIEGAG.
DR   BioCyc; CSAL290398:CSAL_1163-MON; -.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0004141; F:dethiobiotin synthase activity; IEA:HAMAP.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:HAMAP.
DR   GO; GO:0009102; P:biotin biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00336; -; 1.
DR   InterPro; IPR004472; BioD_synth.
DR   PIRSF; PIRSF006755; DTB_synth; 1.
DR   TIGRFAMs; TIGR00347; bioD; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Biotin biosynthesis; Complete proteome; Ligase;
KW   Magnesium; Nucleotide-binding.
FT   CHAIN         1    237       Dethiobiotin synthetase.
FT                                /FTId=PRO_0000302497.
FT   NP_BIND       8     16       ATP (By similarity).
SQ   SEQUENCE   237 AA;  24790 MW;  798C42FAF3A66E1F CRC64;
     MTTYFVTGTD TDAGKTLVAS GLLALARRRG LTTLGLKPVA SGCESTTEGL RNIDALTLQA
     QSMPTPPYAT LNPYAYAPAI APHLAARRAG RIPTLDALVA HVADPLAEKR DLTLIEGAGG
     WRVPLNDDED LAGLAVRLEL PVILVVGLEL GCLNHARLSA EAIRADGLPL AGWVGNLIDP
     GLSFDEVADE ACYRDNLATL ERTLEAPCLG IVPRLAAATP DARAHAAADY LTLPGDA
//