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Q1QXE1 (BETA1_CHRSD) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Choline dehydrogenase
Short name=CDH
Short name=CHD
EC=1.1.99.1
Gene names
Name:betA
Ordered Locus Names:Csal_1514
OrganismChromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768) [Complete proteome] [HAMAP]
Taxonomic identifier290398 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Halomonadaceae › Chromohalobacter

Protein attributes

Sequence length560 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine By similarity. HAMAP MF_00750

Catalytic activity

Choline + acceptor = betaine aldehyde + reduced acceptor. HAMAP MF_00750

Cofactor

FAD By similarity. HAMAP MF_00750

Pathway

Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1. HAMAP MF_00750

Sequence similarities

Belongs to the GMC oxidoreductase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 560560Choline dehydrogenase HAMAP MF_00750
PRO_0000245316

Regions

Nucleotide binding8 – 3730FAD Potential

Sites

Active site4751 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q1QXE1 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: 8C6D127276CBC454

FASTA56062,246
        10         20         30         40         50         60 
MTQAREYDYI IIGAGSAGNV LATRLTEDPD VQVLLLEAGG PDYRFDFRTQ MPAALAYPLQ 

        70         80         90        100        110        120 
GKRYNWAFET DPEPYMNNRR MECGRGKGLG GSSLINGMCY LRGNALDYDN WAKIPGLEDW 

       130        140        150        160        170        180 
NYLQCLPYFK RAETRDIGPN DYHGGDGPVS VATPKEGNNE LYGAFIRAGI EAGYPATEDV 

       190        200        210        220        230        240 
NGYQQEGFGP MDRTTTPNGR RASTARGYLD IAKQRPNLTI ETHATTDVIE FEGKRAVGVS 

       250        260        270        280        290        300 
YERKGQAQRV RARREVLLCA GAIASPQILQ RSGVGNPEHL EEFDIPVVHE LPGVGENLQD 

       310        320        330        340        350        360 
HLEMYIQYEC KKPISLYPAL KWYNQPKIGA EWLFFGKGIG ASNQFEAAGF IRTNDQEEWP 

       370        380        390        400        410        420 
NLQYHFLPIA ISYNGKSAVQ AHGFQAHVGS MRSMSRGRIR LTSRDPKAAP SILFNYMSHD 

       430        440        450        460        470        480 
KDWQEFRDAI RITREIIEQP TMDEYRGREI SPGPNVQSDA ELDEFVRQHA ETAYHPAGSC 

       490        500        510        520        530        540 
KMGSADDAMA VVDGAGRVHG LEGLRVIDAS IMPVIATGNL NAPTIMIAEK MADKVRGRDP 

       550        560 
LPPAKVDYYV ANGAPARRRA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000285 Genomic DNA. Translation: ABE58867.1.
RefSeqYP_573566.1. NC_007963.1.

3D structure databases

ProteinModelPortalQ1QXE1.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ1QXE1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4029210.
GenomeReviewsGene locus Csal_1514 in contig CP000285_GR.
KEGGcsa:Csal_1514.
NMPDRfig|290398.4.peg.2343.
PATRIC21446808. VBIChrSal113723_1521.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2303.
HOGENOMHBG734713.
OMARSTAPYY.
ProtClustDBPRK02106.

Enzyme and pathway databases

BioCycCSAL290398:CSAL_1514-MONOMER.

Family and domain databases

HAMAPMF_00750. Choline_dehydrogen.
[Tree]
InterProIPR011533. Choline_dehydrogenase.
IPR012132. GMC_OxRdtase.
IPR000172. GMC_OxRdtase_N.
IPR007867. GMC_OxRtase_C.
[Graphical view]
KOK00108.
PfamPF05199. GMC_oxred_C. 1 hit.
PF00732. GMC_oxred_N. 1 hit.
[Graphical view]
PIRSFPIRSF000137. Alcohol_oxidase. 1 hit.
TIGRFAMsTIGR01810. BetA. 1 hit.
PROSITEPS00623. GMC_OXRED_1. 1 hit.
PS00624. GMC_OXRED_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBETA1_CHRSD
AccessionPrimary (citable) accession number: Q1QXE1
Entry history
Integrated into UniProtKB/Swiss-Prot: July 11, 2006
Last sequence update: May 16, 2006
Last modified: January 25, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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