ID   GLPK_CHRSD              Reviewed;         501 AA.
AC   Q1QVQ3;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2006, sequence version 1.
DT   16-JUN-2009, entry version 28.
DE   RecName: Full=Glycerol kinase;
DE            EC=2.7.1.30;
DE   AltName: Full=ATP:glycerol 3-phosphotransferase;
DE   AltName: Full=Glycerokinase;
DE            Short=GK;
GN   Name=glpK; OrderedLocusNames=Csal_2104;
OS   Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB
OS   13768).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Oceanospirillales;
OC   Halomonadaceae; Chromohalobacter.
OX   NCBI_TaxID=290398;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T.,
RA   Bruce D., Han C., Tapia R., Gilna P., Saunders E., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Csonka L.N.,
RA   O'Conner K., Vreeland R.H., Oren A., Vargas C., Nieto J., Arahal D.R.,
RA   Goodner B., Wheeler C., Hall P., Ewing A., Benson L., McBeath D.,
RA   Canovas D., Richardson P.;
RT   "Complete sequence of Chromohalobacter salexigens DSM 3043.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Key enzyme in the regulation of glycerol uptake and
CC       metabolism.
CC   -!- CATALYTIC ACTIVITY: ATP + glycerol = ADP + sn-glycerol 3-
CC       phosphate.
CC   -!- PATHWAY: Polyol metabolism; glycerol degradation via glycerol
CC       kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
CC   -!- SIMILARITY: Belongs to the FGGY kinase family.
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DR   EMBL; CP000285; ABE59455.1; -; Genomic_DNA.
DR   RefSeq; YP_574154.1; -.
DR   GeneID; 4029249; -.
DR   GenomeReviews; CP000285_GR; Csal_2104.
DR   KEGG; csa:Csal_2104; -.
DR   NMPDR; fig|290398.4.peg.2121; -.
DR   HOGENOM; Q1QVQ3; -.
DR   OMA; Q1QVQ3; KFADNWR.
DR   BioCyc; CSAL290398:CSAL_2104-MON; -.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0004370; F:glycerol kinase activity; IEA:HAMAP.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:HAMAP.
DR   HAMAP; MF_00186; -; 1.
DR   InterPro; IPR000577; Carb_kinase_FGGY.
DR   InterPro; IPR018485; Carb_kinase_FGGY_C.
DR   InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR   InterPro; IPR018484; Carb_kinase_FGGY_N.
DR   InterPro; IPR005999; Glycerol_kin.
DR   PANTHER; PTHR10196; FGGY_kin; 1.
DR   PANTHER; PTHR10196:SF9; Glycerol_kin; 1.
DR   Pfam; PF02782; FGGY_C; 1.
DR   Pfam; PF00370; FGGY_N; 1.
DR   TIGRFAMs; TIGR01311; glycerol_kin; 1.
DR   PROSITE; PS00933; FGGY_KINASES_1; 1.
DR   PROSITE; PS00445; FGGY_KINASES_2; FALSE_NEG.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Glycerol metabolism; Kinase;
KW   Nucleotide-binding; Transferase.
FT   CHAIN         1    501       Glycerol kinase.
FT                                /FTId=PRO_1000020717.
FT   NP_BIND     409    413       ATP (By similarity).
FT   BINDING      12     12       Substrate (By similarity).
FT   BINDING      16     16       ATP (By similarity).
FT   BINDING      82     82       Substrate (By similarity).
FT   BINDING     134    134       Substrate (By similarity).
FT   BINDING     243    243       Substrate (By similarity).
FT   BINDING     265    265       ATP (By similarity).
FT   BINDING     308    308       ATP; via carbonyl oxygen (By similarity).
SQ   SEQUENCE   501 AA;  55010 MW;  792AC17A5476D062 CRC64;
     MHSYLLSIDQ GTTSSRAILF DRQGRVAGVA QEEFAQHFPA SGWVEHDAED IWQSVLRTCR
     QVMESTGASI EEIAGIGMTN QRETTLLWDR RTGEPLHRAI VWQDRRTGAY CQSLIDAGHE
     AFIQSRTGLL IDPYFSATKL RWLLENVPGA RERAERGELA FGTVDTFLLW RLTGGREHAT
     DATNASRTCL FNIHTQQWDE ALLSLFEIPA SLLPEVKDSS ADFGRAEPHW LGGPLPIAGI
     AGDQQAALVG QTCFAPGMAK STYGTGCFMI INTGEKAEVS HNRLLTTVAY RLNGKTTYAM
     EGSIFVAGAT VQWLRDGLKL FADASETEAL ARQTRAGHGV YLVPAFTGLG APHWDPGARG
     AIFGLTRDTG IAEIVAAGLQ AVCYQTRDLQ ACMDDDIEAS AGRLRVDGGM VSNNWVMQFL
     ADMLGVPVDR PTVLETTALG AAYLAGLQLG WYADLDEIAG LWRCERTFEP SMEEAERERL
     YRGWLDAIER VKCSAETRGR A
//