Q1QUD2 (MQO_CHRSD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4

Alternative name(s):
MQO
Malate dehydrogenase [quinone]

Gene names

Name:	mqo
Ordered Locus Names:	Csal_2579

Organism

Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768) [Complete proteome] [HAMAP]

Taxonomic identifier

290398 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Halomonadaceae › Chromohalobacter

Protein attributes

Sequence length	508 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212
Cofactor	FAD By similarity. HAMAP MF_00212
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	malate dehydrogenase (menaquinone) activity Inferred from electronic annotation. Source: EC malate dehydrogenase (quinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 508	508	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_1000023794

Sequences

	Sequence		Length	Mass (Da)
	Q1QUD2 [UniParc]. Last modified May 16, 2006. Version 1. Checksum: 2EA022A8F22EBD36	FASTA	508	55,933
	10 20 30 40 50 60 MVGTHMDESV DIVLVGAGVM SATLATLLHE LEPDARIEII ERLDSTASES SFAWNNAGTG 70 80 90 100 110 120 HAGLCELNYT PRADDGSISL DKAIHTNTLF EESKQFWSYL VEKGNLGDPG RFVHPVPHMS 130 140 150 160 170 180 FVRGEDDVRF LRDRYHAMRE HPCFEGMEYT EDRSVIGQWA PLLLDGREGD EPLAATRVAT 190 200 210 220 230 240 GTDVDFGALT RQLLARLEEK PDEQVRITTG QTVEDLTRNE DGSWRIKIAG NDDTQRTLNA 250 260 270 280 290 300 RFVFLGAGGA SLHLLQKSGI PEGKGYAGFP VSGQWLRCDK PEIVSRHNAK VYSKAPIGAP 310 320 330 340 350 360 PMSVPHLDTR NVDGSPSLLF GPFAGFTTKF LKTGSVMDLA KSVRSSNLSP MLSVARDNFS 370 380 390 400 410 420 LVKYLIDQVR LSHEQRVDEL RTFYPMAKND DWRLEVAGQR VQVIKKDPQK GGILQFGTEV 430 440 450 460 470 480 VAASDGSLAA LLGASPGAST ATSIMLNLVE QCFPEKFASQ AWQQRLHDLV PARAETLADN 490 500 GDLLRDVRRR THDTLKLVDT QPSPEPVT

References

[1]

"Complete sequence of Chromohalobacter salexigens DSM 3043." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Saunders E., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Csonka L.N., O'Conner K., Vreeland R.H., Oren A., Vargas C., Nieto J., Arahal D.R., Goodner B., Wheeler C., Hall P., Ewing A., Benson L., McBeath D., Canovas D., Richardson P. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 3043 / ATCC BAA-138 / NCIMB 13768.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000285 Genomic DNA. Translation: ABE59926.1.
RefSeq	YP_574625.1. NC_007963.1.
3D structure databases
ProteinModelPortal	Q1QUD2.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1QUD2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4027115.
GenomeReviews	Gene locus Csal_2579 in contig CP000285_GR.
KEGG	csa:Csal_2579.
NMPDR	fig|290398.4.peg.2035.
PATRIC	21449012. VBIChrSal113723_2593.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0579.
HOGENOM	HBG289663.
OMA	NTQFEVS.
ProtClustDB	PRK05257.
Enzyme and pathway databases
BioCyc	CSAL290398:CSAL_2579-MONOMER.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
KO	K00116.
PANTHER	PTHR13847:SF14. PTHR13847:SF14. 1 hit.
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. Mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_CHRSD

Accession

Primary (citable) accession number: Q1QUD2

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	May 16, 2006
Last modified:	January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program