ID   AROE_CHRSD              Reviewed;         271 AA.
AC   Q1QTK0;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2006, sequence version 1.
DT   16-JUN-2009, entry version 31.
DE   RecName: Full=Shikimate dehydrogenase;
DE            EC=1.1.1.25;
GN   Name=aroE; OrderedLocusNames=Csal_2862;
OS   Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB
OS   13768).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Oceanospirillales;
OC   Halomonadaceae; Chromohalobacter.
OX   NCBI_TaxID=290398;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T.,
RA   Bruce D., Han C., Tapia R., Gilna P., Saunders E., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Csonka L.N.,
RA   O'Conner K., Vreeland R.H., Oren A., Vargas C., Nieto J., Arahal D.R.,
RA   Goodner B., Wheeler C., Hall P., Ewing A., Benson L., McBeath D.,
RA   Canovas D., Richardson P.;
RT   "Complete sequence of Chromohalobacter salexigens DSM 3043.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: Shikimate + NADP(+) = 3-dehydroshikimate +
CC       NADPH.
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and PEP:
CC       step 4/7.
CC   -!- SIMILARITY: Belongs to the shikimate dehydrogenase family.
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DR   EMBL; CP000285; ABE60208.1; -; Genomic_DNA.
DR   RefSeq; YP_574907.1; -.
DR   GeneID; 4028664; -.
DR   GenomeReviews; CP000285_GR; Csal_2862.
DR   KEGG; csa:Csal_2862; -.
DR   NMPDR; fig|290398.4.peg.2556; -.
DR   HOGENOM; Q1QTK0; -.
DR   OMA; Q1QTK0; YDMMYGR.
DR   BioCyc; CSAL290398:CSAL_2862-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0050661; F:NADP or NADPH binding; IEA:InterPro.
DR   GO; GO:0004764; F:shikimate 5-dehydrogenase activity; IEA:HAMAP.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic pro...; IEA:HAMAP.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   HAMAP; MF_00222; -; 1.
DR   InterPro; IPR011342; Quinate/shikimate_5-DH.
DR   InterPro; IPR013708; Shikimate_DH-bd_N.
DR   InterPro; IPR006151; Shikm_DH/Glu-tRNA_Rdtase.
DR   Pfam; PF01488; Shikimate_DH; 1.
DR   Pfam; PF08501; Shikimate_dh_N; 1.
DR   TIGRFAMs; TIGR00507; aroE; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis; Aromatic amino acid biosynthesis;
KW   Complete proteome; NADP; Oxidoreductase.
FT   CHAIN         1    271       Shikimate dehydrogenase.
FT                                /FTId=PRO_1000021272.
FT   NP_BIND     128    132       NADP (By similarity).
FT   ACT_SITE     67     67       Proton acceptor (Potential).
SQ   SEQUENCE   271 AA;  28705 MW;  1732DC63048AEB7B CRC64;
     MSDDRYCVFG NPVAHSRSPR IHALFAEQCG QAMTYEAIEA PREDFAGAWH AFVAAGGCGA
     NVTVPFKEDA FRLADVLSQR ARRAGAVNTL VRGRDGRTYA DTTDGVGLVR DLEAHGVTLE
     GARILILGAG GAVRGVLDPL LAKAPSCLHI ANRTASKAVR LAEEASPEGR VTGGGYSELD
     GAFDVVINGT SASLGGELPP LPDTLLAADG VAYDMMYAAE PTVFLQWAAA HGGRGIDGLG
     MLIEQAAESF FLWRQVRPDT APVRETLRRE L
//