Reviewed, UniProtKB/Swiss-Prot Q1QTJ9 (HEM6_CHRSD)

Names and origin

Protein names

Recommended name:
    Coproporphyrinogen III oxidase, aerobic
      Short name=Coproporphyrinogenase
      Short name=Coprogen oxidase
    EC=1.3.3.3

Gene names

Name:	hemF
Ordered Locus Names:	Csal_2863

Organism

Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768) [Complete proteome] [HAMAP]

Taxonomic identifier

290398 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Halomonadaceae › Chromohalobacter

Protein attributes

Sequence length	307 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Coproporphyrinogen-III + O(2) + 2 H(+) = protoporphyrinogen-IX + 2 CO(2) + 2 H(2)O.
Pathway	Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen III (O2 route): step 1/1.
Subcellular location	CytoplasmBy similarity.
Sequence similarities	Belongs to the aerobic coproporphyrinogen III oxidase family.

Ontologies

Keywords
Biological process	Porphyrin biosynthesis
Cellular component	Cytoplasm
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW porphyrin biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: HAMAP
Molecular function	coproporphyrinogen oxidase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 307	307	Coproporphyrinogen III oxidase, aerobic		PRO_1000019465

Sequences

	Sequence		Length	Mass (Da)
	Q1QTJ9-1 [UniParc]. Last modified May 16, 2006. Version 1. Checksum: 3087254D1FD66BFD	FASTA	307	35,297
	10 20 30 40 50 60 MAHPHLDKVK EYLLDLQDRL CDGLAAEEGD TAFREDSWTR EAGGGGRSRV IENGEVFEKG 70 80 90 100 110 120 GVNFSHVFGE RLPASASAAR PELAGRSFHA VGVSWVLHPR NPHVPTAHGN VRFFIAEKEG 130 140 150 160 170 180 AEPVWWFGGG FDLTPFYPVF EDVVHWHRVA QETCAPFGDD VYPRFKRWCD EYFTLHHRDE 190 200 210 220 230 240 TRGVGGLFFD DLNEWEFERC FAFQRAVGDA FLEAYVPIVR RRQATEYGER ERDFQAFRRG 250 260 270 280 290 300 RYVEFNLVWD RGTLFGLQSG GRTESILMSM PPLAQWQYCW TPEPGSPEAR LADEFLTPRE WLEEAEA

References

[1]

"Complete sequence of Chromohalobacter salexigens DSM 3043." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Saunders E., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Csonka L.N., O'Conner K., Vreeland R.H., Oren A., Vargas C., Nieto J., Arahal D.R., Goodner B., Wheeler C., Hall P., Ewing A., Benson L., McBeath D., Canovas D., Richardson P. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000285 Genomic DNA. Translation: ABE60209.1.
RefSeq	YP_574908.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4028665.
GenomeReviews	Gene locus Csal_2863 in contig CP000285_GR.
KEGG	csa:Csal_2863.
NMPDR	fig|290398.4.peg.2557.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q1QTJ9.
Enzyme and pathway databases
BioCyc	CSAL290398:CSAL_2863-MON.
Family and domain databases
HAMAP	MF_00333. [Tree]
InterPro	IPR001260. Coprogen_oxidas. [Graphical view]
Gene3D	G3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
PANTHER	PTHR10755. Coprogen_oxidas. 1 hit.
Pfam	PF01218. Coprogen_oxidas. 1 hit. [Graphical view]
PIRSF	PIRSF000166. Coproporphyri_ox. 1 hit.
PRINTS	PR00073. COPRGNOXDASE.
PROSITE	PS01021. COPROGEN_OXIDASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HEM6_CHRSD

Accession

Primary (citable) accession number: Q1QTJ9

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	May 16, 2006
Last modified:	November 4, 2008
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)