Reviewed, UniProtKB/Swiss-Prot Q1QSV1 (DAPF_CHRSD)

Names and origin

Protein names

Recommended name:
    Diaminopimelate epimerase
      Short name=DAP epimerase
    EC=5.1.1.7

Gene names

Name:	dapF
Ordered Locus Names:	Csal_3113

Organism

Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768) [Complete proteome] [HAMAP]

Taxonomic identifier

290398 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Halomonadaceae › Chromohalobacter

Protein attributes

Sequence length	277 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate. HAMAP MF_00197
Pathway	Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-diaminopimelate from LL-diaminopimelate: step 1/1. HAMAP MF_00197
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the diaminopimelate epimerase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Lysine biosynthesis
Cellular component	Cytoplasm
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lysine biosynthetic process via diaminopimelate Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	diaminopimelate epimerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 277	277	Diaminopimelate epimerase HAMAP MF_00197		PRO_1000011868
Sites
	Active site	75	1	By similarity
	Active site	219	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q1QSV1-1 [UniParc]. Last modified May 16, 2006. Version 1. Checksum: 07A121EAA12FD10B	FASTA	277	30,583
	10 20 30 40 50 60 MLLHFTKMHG LGNDFVVIDL ITQRARLDTE RIRQLADRHV GIGFDQLLLV EPPRDPEMDF 70 80 90 100 110 120 RYRIFNADGN EVENCGNGAR CFARFVRDNR LTHKREIRVE TQAGPLTLRV EDDERIRVDM 130 140 150 160 170 180 GVPRFAPEVV PFDAPADAPA HCLEVDGETW DIGAVSMGNP HAVLRVDDVA QAPVARLGPL 190 200 210 220 230 240 IERHPRFPRG VNVGFLQVVS RHEARLRVFE RGSGETLACG TGACAAVAHG IRRGWLESPV 250 260 270 DVHLPGGTLT LAWPAPDASL MMTGPATSVF EGRIALP

References

[1]

"Complete sequence of Chromohalobacter salexigens DSM 3043." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Saunders E., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Csonka L.N., O'Conner K., Vreeland R.H., Oren A., Vargas C., Nieto J., Arahal D.R., Goodner B., Wheeler C., Hall P., Ewing A., Benson L., McBeath D., Canovas D., Richardson P. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000285 Genomic DNA. Translation: ABE60457.1.
RefSeq	YP_575156.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4028754.
GenomeReviews	Gene locus Csal_3113 in contig CP000285_GR.
KEGG	csa:Csal_3113.
NMPDR	fig|290398.4.peg.3022.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q1QSV1.
OMA	Q1QSV1. PHAVLRV.
Enzyme and pathway databases
BioCyc	CSAL290398:CSAL_3113-MON.
Family and domain databases
HAMAP	MF_00197. [Tree]
InterPro	IPR001653. DAP_epimerase. IPR018510. DAP_epimerase_CS. [Graphical view]
Pfam	PF01678. DAP_epimerase. 2 hits. [Graphical view]
TIGRFAMs	TIGR00652. DapF. 1 hit.
PROSITE	PS01326. DAP_EPIMERASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DAPF_CHRSD

Accession

Primary (citable) accession number: Q1QSV1

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	May 16, 2006
Last modified:	June 16, 2009
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)