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Reviewed, UniProtKB/Swiss-Prot Q1QSR9 (TRMB_CHRSD)

Last modified June 16, 2009. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    tRNA (guanine-N(7)-)-methyltransferase
    EC=2.1.1.33
Alternative name(s):
    tRNA(m7G46)-methyltransferase
Gene names
Name: trmB
Ordered Locus Names: Csal_3145
OrganismChromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768) [Complete proteome] [HAMAP]
Taxonomic identifier290398 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Halomonadaceae › Chromohalobacter

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Protein attributes

Sequence length246 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Function

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity.

Catalytic activity

S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N(7)-methylguanine. HAMAP MF_01057

Pathway

tRNA modification; N(7)-methylguanine-tRNA biosynthesis. HAMAP MF_01057

Sequence similarities

Belongs to the methyltransferase superfamily. TrmB family.

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Ontologies

Keywords
   Biological processtRNA processing
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processtRNA modification

Inferred from electronic annotation. Source: HAMAP

   Molecular functiontRNA (guanine-N7-)-methyltransferase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 246246tRNA (guanine-N(7)-)-methyltransferase HAMAP MF_01057
PRO_0000288137

Regions

Region224 – 2274Substrate binding Potential

Sites

Binding site741S-adenosyl-L-methionine By similarity
Binding site991S-adenosyl-L-methionine By similarity
Binding site1261S-adenosyl-L-methionine By similarity
Binding site1491S-adenosyl-L-methionine By similarity
Binding site1531Substrate By similarity
Binding site1851Substrate Potential

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Sequences

Sequence LengthMass (Da)Tools
Q1QSR9-1 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: A691A52734B6E9B4

FASTA24627,368
        10         20         30         40         50         60 
MSDSSSSSEN APATPESPGR PPRGIKSYVL RAGRMTAAQS RGLEEVWPRL GLSVAEGRQS 

        70         80         90        100        110        120 
LEALFGRRAP CVVEVGFGMG QSLVEQAAAN PETDFIGIEV HAPGVGKLLD EADKRGLTNL 

       130        140        150        160        170        180 
RVYRDDALEV LDKCLPESSL TGLQLFFPDP WPKKKHHKRR IVQPAFVELV RTRLAPHGYL 

       190        200        210        220        230        240 
HMATDWEAYA EHMVEVMEEA PGYRNTAPPE SAPYVPRPEF RPLTKFESRG ERLGHGVWDL 


IYARVE

« Hide

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References

[1]"Complete sequence of Chromohalobacter salexigens DSM 3043."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Saunders E., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Csonka L.N., O'Conner K., Vreeland R.H., Oren A., Vargas C., Nieto J., Arahal D.R., Goodner B., Wheeler C., Hall P., Ewing A., Benson L., McBeath D., Canovas D., Richardson P.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

CP000285 Genomic DNA. Translation: ABE60489.1.
RefSeqYP_575188.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID4028612.
GenomeReviewsGene locus Csal_3145 in contig CP000285_GR.
KEGGcsa:Csal_3145.
NMPDRfig|290398.4.peg.3137.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ1QSR9.
OMAQ1QSR9. TKFENRG.

Enzyme and pathway databases

BioCycCSAL290398:CSAL_3145-MON.

Family and domain databases

HAMAPMF_01057.
[Tree]
InterProIPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PANTHERPTHR23417:SF1. Methyltransf_4. 1 hit.
PfamPF02390. Methyltransf_4. 1 hit.
[Graphical view]
TIGRFAMsTIGR00091. CHP91. 1 hit.
ProtoNetSearch...

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Entry information

Entry nameTRMB_CHRSD
AccessionPrimary (citable) accession number: Q1QSR9
Entry history
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: May 16, 2006
Last modified: June 16, 2009
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents