SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q1QSR0

- MASZ_CHRSD

UniProt

Q1QSR0 - MASZ_CHRSD

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Malate synthase G
Gene
glcB, Csal_3154
Organism
Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA By similarity.UniRule annotation

Catalytic activityi

Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA.UniRule annotation

Cofactori

Magnesium By similarity.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei118 – 1181Acetyl-CoA; via carbonyl oxygen By similarity
Binding sitei276 – 2761Acetyl-CoA By similarity
Binding sitei313 – 3131Acetyl-CoA By similarity
Active sitei340 – 3401Proton acceptor By similarity
Binding sitei340 – 3401Glyoxylate By similarity
Metal bindingi442 – 4421Magnesium By similarity
Binding sitei442 – 4421Glyoxylate By similarity
Metal bindingi470 – 4701Magnesium By similarity
Binding sitei551 – 5511Acetyl-CoA; via carbonyl oxygen By similarity
Active sitei650 – 6501Proton donor By similarity

GO - Molecular functioni

  1. malate synthase activity Source: UniProtKB-HAMAP
  2. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

  1. glyoxylate cycle Source: UniProtKB-HAMAP
  2. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Glyoxylate bypass, Tricarboxylic acid cycle

Keywords - Ligandi

Magnesium, Metal-binding

Enzyme and pathway databases

UniPathwayiUPA00703; UER00720.

Names & Taxonomyi

Protein namesi
Recommended name:
Malate synthase G (EC:2.3.3.9)
Gene namesi
Name:glcB
Ordered Locus Names:Csal_3154
OrganismiChromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768)
Taxonomic identifieri290398 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesHalomonadaceaeChromohalobacter
ProteomesiUP000000239: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 742742Malate synthase GUniRule annotation
PRO_1000056901Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei636 – 6361Cysteine sulfenic acid (-SOH) By similarity
Modified residuei707 – 7071Cysteine sulfenic acid (-SOH) By similarity

Keywords - PTMi

Oxidation

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi290398.Csal_3154.

Structurei

3D structure databases

ProteinModelPortaliQ1QSR0.
SMRiQ1QSR0. Positions 1-739.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni125 – 1262Acetyl-CoA binding By similarity
Regioni467 – 4704Glyoxylate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2225.
HOGENOMiHOG000220740.
KOiK01638.
OMAiPANTLKM.
OrthoDBiEOG6HJ286.

Family and domain databases

Gene3Di2.170.170.11. 2 hits.
HAMAPiMF_00641. Malate_synth_G.
InterProiIPR011076. Malate_synth-like.
IPR023310. Malate_synth_G_beta_sub_dom.
IPR001465. Malate_synthase.
IPR006253. Malate_synthG.
[Graphical view]
PfamiPF01274. Malate_synthase. 1 hit.
[Graphical view]
SUPFAMiSSF51645. SSF51645. 1 hit.
TIGRFAMsiTIGR01345. malate_syn_G. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1QSR0-1 [UniParc]FASTAAdd to Basket

« Hide

MTDRTTRHRL QVASQLDRFI NDEALPGTGV DPEAFWAGFD ALVHELVPTN    50
RDLLAERERL QDELDAWHKA NPGPVRDMAA YRAFLKDIGY LVEAPAKVQA 100
TTANVDDEIA VQAGPQLVVP VSNARYALNA ANARWGSLYD ALYGTDVIPE 150
TDGAEKSQGY NPKRGEKVIA YARGVLDQAA PLAEGTHAEA SAYALRDGKL 200
VVTLQGGGET GLADPAQLVG YRGEAQAPTA VLLANHGLHL EVQFDATHPI 250
GKTDPAHVKD VLVEAAVSTI MDCEDSVAAV DADDKTLVYR NWLGLMKGDL 300
EERFDKGGKT VTRALNPDRD YTVPGGGELR LPGRSLLFVR NVGHLMTTPA 350
VLDGDGNEIP EGMLDGVVTS LLAIHDLKKG DGAAPSATAP EAKRNSRTGS 400
VYIVKPKMHG PREVAFANSL FMRIEDMLGL PRDTLKMGIM DEERRTSINL 450
DACIHEAASR VAFINTGFLD RTGDEMHTAM EAGPMLRKGE MKGTKWIAAY 500
EKNNVQTGLA CGLRGRAQIG KGMWAMPELM AAMLEQKIGH PQAGATTAWV 550
PSPTAAVLHA LHYHQVDVAT IQRELEAKPG GDFLDDLLTV PVVESAASGA 600
NKSPSWSDDE IQQELDNNCQ GILGYVVRWV EHGVGCSKVP DIHDVGLMED 650
RATLRISSQH IANWLHHGIV SEARVRETLE RMAKVVDDQN AHDPDYTPMT 700
SHLAESCAFQ AASDLIFKGR EQPAGYTEPL LHHWRAVHKA KS 742
Length:742
Mass (Da):80,564
Last modified:May 16, 2006 - v1
Checksum:i52D50E6BAB982917
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000285 Genomic DNA. Translation: ABE60498.1.
RefSeqiYP_575197.1. NC_007963.1.

Genome annotation databases

EnsemblBacteriaiABE60498; ABE60498; Csal_3154.
GeneIDi4028621.
KEGGicsa:Csal_3154.
PATRICi21450192. VBIChrSal113723_3174.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000285 Genomic DNA. Translation: ABE60498.1 .
RefSeqi YP_575197.1. NC_007963.1.

3D structure databases

ProteinModelPortali Q1QSR0.
SMRi Q1QSR0. Positions 1-739.
ModBasei Search...

Protein-protein interaction databases

STRINGi 290398.Csal_3154.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABE60498 ; ABE60498 ; Csal_3154 .
GeneIDi 4028621.
KEGGi csa:Csal_3154.
PATRICi 21450192. VBIChrSal113723_3174.

Phylogenomic databases

eggNOGi COG2225.
HOGENOMi HOG000220740.
KOi K01638.
OMAi PANTLKM.
OrthoDBi EOG6HJ286.

Enzyme and pathway databases

UniPathwayi UPA00703 ; UER00720 .

Family and domain databases

Gene3Di 2.170.170.11. 2 hits.
HAMAPi MF_00641. Malate_synth_G.
InterProi IPR011076. Malate_synth-like.
IPR023310. Malate_synth_G_beta_sub_dom.
IPR001465. Malate_synthase.
IPR006253. Malate_synthG.
[Graphical view ]
Pfami PF01274. Malate_synthase. 1 hit.
[Graphical view ]
SUPFAMi SSF51645. SSF51645. 1 hit.
TIGRFAMsi TIGR01345. malate_syn_G. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 3043 / ATCC BAA-138 / NCIMB 13768.

Entry informationi

Entry nameiMASZ_CHRSD
AccessioniPrimary (citable) accession number: Q1QSR0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 16, 2006
Last modified: May 14, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi