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Protein

Probable chorismate pyruvate-lyase

Gene

ubiC

Organism
Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.UniRule annotation

Catalytic activityi

Chorismate = 4-hydroxybenzoate + pyruvate.UniRule annotation

Pathwayi: ubiquinone biosynthesis

This protein is involved in the pathway ubiquinone biosynthesis, which is part of Cofactor biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway ubiquinone biosynthesis and in Cofactor biosynthesis.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei79 – 791SubstrateUniRule annotation
Binding sitei115 – 1151Substrate; via amide nitrogenUniRule annotation
Binding sitei168 – 1681SubstrateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Ubiquinone biosynthesis

Keywords - Ligandi

Pyruvate

Enzyme and pathway databases

UniPathwayiUPA00232.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable chorismate pyruvate-lyaseUniRule annotation (EC:4.1.3.40UniRule annotation)
Short name:
CLUniRule annotation
Short name:
CPLUniRule annotation
Gene namesi
Name:ubiCUniRule annotation
Ordered Locus Names:Csal_3251
OrganismiChromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768)
Taxonomic identifieri290398 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesHalomonadaceaeChromohalobacter
Proteomesi
  • UP000000239 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 183183Probable chorismate pyruvate-lyasePRO_0000255905Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi290398.Csal_3251.

Structurei

3D structure databases

ProteinModelPortaliQ1QSG3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UbiC family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105VEI. Bacteria.
COG3161. LUCA.
HOGENOMiHOG000137785.
KOiK03181.
OMAiEVCHYPE.
OrthoDBiEOG6GBM9Z.

Family and domain databases

Gene3Di3.40.1410.10. 1 hit.
HAMAPiMF_01632. UbiC.
InterProiIPR007440. Chorismate--pyruvate_lyase.
IPR028978. Chorismate_lyase_/UTRA_dom.
[Graphical view]
PfamiPF04345. Chor_lyase. 1 hit.
[Graphical view]
SUPFAMiSSF64288. SSF64288. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1QSG3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSPDRFPGWP HWLPIAAQRP RMSPDWWPWV ASRDSLTARL RIASPRPFSV
60 70 80 90 100
RLLTQGVTRP RLDEAQALGL PHRTHVWHRE VLLRLGNASW VAARSVAPLE
110 120 130 140 150
GLSGARLCTL GERSLGSWLF RQPNLERGPI EAIRAPAMTG LDAWRGDAGP
160 170 180
WGRRSLLRVG RTRILVQEFF LAAMAADLSL PSR
Length:183
Mass (Da):20,588
Last modified:May 16, 2006 - v1
Checksum:i109ECB074EE0561C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000285 Genomic DNA. Translation: ABE60595.1.
RefSeqiWP_011508541.1. NC_007963.1.

Genome annotation databases

EnsemblBacteriaiABE60595; ABE60595; Csal_3251.
KEGGicsa:Csal_3251.
PATRICi21450380. VBIChrSal113723_3267.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000285 Genomic DNA. Translation: ABE60595.1.
RefSeqiWP_011508541.1. NC_007963.1.

3D structure databases

ProteinModelPortaliQ1QSG3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi290398.Csal_3251.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABE60595; ABE60595; Csal_3251.
KEGGicsa:Csal_3251.
PATRICi21450380. VBIChrSal113723_3267.

Phylogenomic databases

eggNOGiENOG4105VEI. Bacteria.
COG3161. LUCA.
HOGENOMiHOG000137785.
KOiK03181.
OMAiEVCHYPE.
OrthoDBiEOG6GBM9Z.

Enzyme and pathway databases

UniPathwayiUPA00232.

Family and domain databases

Gene3Di3.40.1410.10. 1 hit.
HAMAPiMF_01632. UbiC.
InterProiIPR007440. Chorismate--pyruvate_lyase.
IPR028978. Chorismate_lyase_/UTRA_dom.
[Graphical view]
PfamiPF04345. Chor_lyase. 1 hit.
[Graphical view]
SUPFAMiSSF64288. SSF64288. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 3043 / ATCC BAA-138 / NCIMB 13768.

Entry informationi

Entry nameiUBIC_CHRSD
AccessioniPrimary (citable) accession number: Q1QSG3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: May 16, 2006
Last modified: January 20, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.