Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q1QS91 (Q1QS91_NITHX) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
DNA gyrase subunit B RuleBase RU003363 HAMAP MF_01898
EC=5.99.1.3 RuleBase RU003363 HAMAP MF_01898
Gene names
Name:gyrB HAMAP MF_01898
Ordered Locus Names:Nham_0004
OrganismNitrobacter hamburgensis (strain X14 / DSM 10229) [Complete proteome] [HAMAP]
Taxonomic identifier323097 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Nitrobacter

Protein attributes

Sequence length813 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings By similarity. RuleBase RU003363 HAMAP MF_01898

Catalytic activity

ATP-dependent breakage, passage and rejoining of double-stranded DNA. RuleBase RU003363 SAAS SAAS002288 HAMAP MF_01898

Subunit structure

Made up of two chains. The A chain is responsible for DNA breakage and rejoining; the B chain catalyzes ATP hydrolysis. The enzyme forms an A2B2 tetramer By similarity. HAMAP MF_01898

Subcellular location

Cytoplasm By similarity HAMAP MF_01898.

Sequence similarities

Belongs to the type II topoisomerase family. HAMAP MF_01898 RuleBase RU000380

Contains 1 Toprim domain. SAAS SAAS002288 HAMAP MF_01898

Sequences

Sequence LengthMass (Da)Tools
Q1QS91 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: BF59205F7DF7BA5E

FASTA81389,640
        10         20         30         40         50         60 
MNESAGQQLA DTEPAAPVEY GAESIRVLKG LDAVRKRPGM YIGDTDDGSG LHHMVYEVVD 

        70         80         90        100        110        120 
NAIDEALAGH ATRVEVILNA DNSVTVRDDG RGIPVDIHKG EGISAAEVIM TQLHAGGKFD 

       130        140        150        160        170        180 
QNSYKVSGGL HGVGVSVVNA LSSKLILRIW RKDKEHLIEF AHGDAVAPLK VVGEANGKRG 

       190        200        210        220        230        240 
TEVTFLASRE TFTNVEYDFA TLEHRLRELA FLNSGVNILL SDLRRAVEKR EQMMYDGGVV 

       250        260        270        280        290        300 
EFVKYLDRNK KAMVPEPIMI RADMNGLGVE AALWWNDSYH ENVLCFTNNI PQRDGGTHLA 

       310        320        330        340        350        360 
GFRGALTRQV NGYADAMARK ERIALTGDDC REGLTAVLSV KVPDPKFSSQ TKDKLVSSEV 

       370        380        390        400        410        420 
RPVVENVINE ALAAWFEEHP TEAKLIVGKV VEAAAAREAA RKARELTRRK GALDVASLPG 

       430        440        450        460        470        480 
KLADCQERDP AKSELFIVEG DSAGGSAKQG RNREFQAVLP LRGKILNVER ARFDKMLSSE 

       490        500        510        520        530        540 
QIGTLITALG TGIGREDFDL SKLRYHKIIV MTDADVDGAH IRTLLLTFFF RQMPTLIEAG 

       550        560        570        580        590        600 
HLYIAQPPLY KVTRGKSEQY LKDERALEDY LIETGLDDCV FKLATGEDRS GRDLQALVED 

       610        620        630        640        650        660 
ARVIRNVLHN MHGRYNRSVI EQAAIAGVLN PRVTADVATA NAAADYIARR MDALADEVER 

       670        680        690        700        710        720 
GWIGRFTEGE GFSFERTVRG VKDIAMIDDA LLGSADARKL DEYAAKLQEA YPRPGLLRRK 

       730        740        750        760        770        780 
DTETPIHGPV GLFEAVTDAG RKGVALQRYK GLGEMNPDQL WETTLDASER SLLQVKIKEV 

       790        800        810 
DEADDIFTKL MGDVVEPRRE FIQENSLSAN VDV

« Hide

References

[1]"Complete sequence of chromosome of Nitrobacter hamburgensis X14."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Ivanova N., Ward B., Arp D., Klotz M., Stein L., O'Mullan G., Starkenburg S., Sayavedra L., Poret-Peterson A.T., Gentry M.E., Bruce D., Richardson P.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: X14 / DSM 10229.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000319 Genomic DNA. Translation: ABE60906.1.
RefSeqYP_575366.1. NC_007964.1.

3D structure databases

ProteinModelPortalQ1QS91.
SMRQ1QS91. Positions 25-392.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ1QS91.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4029830.
GenomeReviewsGene locus Nham_0004 in contig CP000319_GR.
KEGGnha:Nham_0004.
NMPDRfig|323097.3.peg.253.
PATRIC22687304. VBINitHam61822_0696.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0187.
HOGENOMHBG304889.
OMADCSSRDP.
PhylomeDBQ1QS91.
ProtClustDBPRK14939.

Family and domain databases

HAMAPMF_01898. GyrB.
[Tree]
InterProIPR003594. ATPase-like_ATP-bd.
IPR011557. GyrB.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR001241. Topo_IIA.
IPR013759. Topo_IIA_B/N_ab.
IPR002288. Topo_IIA_B_C.
IPR013506. Topo_IIA_bsu_dom2.
IPR013760. Topo_IIA_cen.
IPR018522. TopoIIA_CS.
IPR006171. Toprim_domain.
[Graphical view]
Gene3DG3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit.
G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit.
G3DSA:3.40.50.670. Topo_IIA_B/N_ab. 2 hits.
KOK02470.
PfamPF00204. DNA_gyraseB. 1 hit.
PF00986. DNA_gyraseB_C. 1 hit.
PF02518. HATPase_c. 1 hit.
PF01751. Toprim. 1 hit.
[Graphical view]
PRINTSPR00418. TPI2FAMILY.
SMARTSM00387. HATPase_c. 1 hit.
SM00433. TOP2c. 1 hit.
[Graphical view]
SUPFAMSSF55874. ATP_bd_ATPase. 1 hit.
SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
SSF56719. Topo_IIA_cen. 1 hit.
TIGRFAMsTIGR01059. GyrB. 1 hit.
PROSITEPS00177. TOPOISOMERASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ1QS91_NITHX
AccessionPrimary (citable) accession number: Q1QS91
Entry history
Integrated into UniProtKB/TrEMBL: May 16, 2006
Last sequence update: May 16, 2006
Last modified: January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info