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Q1QS68

- TRMB_NITHX

UniProt

Q1QS68 - TRMB_NITHX

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Protein
tRNA (guanine-N(7)-)-methyltransferase
Gene
trmB, Nham_0027
Organism
Nitrobacter hamburgensis (strain X14 / DSM 10229)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei80 – 801S-adenosyl-L-methionine By similarity
Binding sitei105 – 1051S-adenosyl-L-methionine By similarity
Binding sitei132 – 1321S-adenosyl-L-methionine By similarity
Active sitei154 – 1541 By similarity
Binding sitei154 – 1541S-adenosyl-L-methionine By similarity
Binding sitei158 – 1581Substrate By similarity
Binding sitei190 – 1901Substrate By similarity

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciNHAM323097:GHP7-27-MONOMER.
UniPathwayiUPA00989.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine-N(7)-)-methyltransferase (EC:2.1.1.33)
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferase
tRNA(m7G46)-methyltransferase
Gene namesi
Name:trmB
Ordered Locus Names:Nham_0027
OrganismiNitrobacter hamburgensis (strain X14 / DSM 10229)
Taxonomic identifieri323097 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeNitrobacter
ProteomesiUP000001953: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 255255tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation
PRO_0000288189Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi323097.Nham_0027.

Structurei

3D structure databases

ProteinModelPortaliQ1QS68.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0220.
HOGENOMiHOG000073969.
KOiK03439.
OMAiRAFYGRR.
OrthoDBiEOG6K6VBC.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01057. tRNA_methyltr_TrmB.
InterProiIPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamiPF02390. Methyltransf_4. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1QS68-1 [UniParc]FASTAAdd to Basket

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MTAAASDPHN PRSSADDTAS PRCESGQGSF FGRRKGHKLR PHQNGLIEHL    50
LPRLSLDPGA SGPSDPATLF GRPVKEMRIE IGFGGGEHLV AEALAFPRTG 100
FIGCEPYVNG MAKILSQIEA HDIGNIRLLA GDASELLAWL PRASLARIDL 150
IHPDPWPKRR HWKRRFVQDA TVAEMARVLR PGGEFRFVSD IADYCAWTLS 200
HLARSPGFLW LAERATDWHN PWPDYTMTRY GRKAEREGRR AAYLRFRRES 250
DAAQA 255
Length:255
Mass (Da):28,542
Last modified:May 16, 2006 - v1
Checksum:i161ABC34515233F7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000319 Genomic DNA. Translation: ABE60929.1.
RefSeqiYP_575389.1. NC_007964.1.

Genome annotation databases

EnsemblBacteriaiABE60929; ABE60929; Nham_0027.
GeneIDi4029794.
KEGGinha:Nham_0027.
PATRICi22687353. VBINitHam61822_0720.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000319 Genomic DNA. Translation: ABE60929.1 .
RefSeqi YP_575389.1. NC_007964.1.

3D structure databases

ProteinModelPortali Q1QS68.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 323097.Nham_0027.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABE60929 ; ABE60929 ; Nham_0027 .
GeneIDi 4029794.
KEGGi nha:Nham_0027.
PATRICi 22687353. VBINitHam61822_0720.

Phylogenomic databases

eggNOGi COG0220.
HOGENOMi HOG000073969.
KOi K03439.
OMAi RAFYGRR.
OrthoDBi EOG6K6VBC.

Enzyme and pathway databases

UniPathwayi UPA00989 .
BioCyci NHAM323097:GHP7-27-MONOMER.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_01057. tRNA_methyltr_TrmB.
InterProi IPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view ]
Pfami PF02390. Methyltransf_4. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
TIGRFAMsi TIGR00091. TIGR00091. 1 hit.
PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: X14 / DSM 10229.

Entry informationi

Entry nameiTRMB_NITHX
AccessioniPrimary (citable) accession number: Q1QS68
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: May 16, 2006
Last modified: June 11, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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