ID   COAA_NITHX              Reviewed;         318 AA.
AC   Q1QRW8;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2006, sequence version 1.
DT   16-JUN-2009, entry version 18.
DE   RecName: Full=Pantothenate kinase;
DE            EC=2.7.1.33;
DE   AltName: Full=Pantothenic acid kinase;
GN   Name=coaA; OrderedLocusNames=Nham_0128;
OS   Nitrobacter hamburgensis (strain X14 / DSM 10229).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Bradyrhizobiaceae; Nitrobacter.
OX   NCBI_TaxID=323097;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Ward B.,
RA   Arp D., Klotz M., Stein L., O'Mullan G., Starkenburg S., Sayavedra L.,
RA   Poret-Peterson A.T., Gentry M.E., Bruce D., Richardson P.;
RT   "Complete sequence of chromosome of Nitrobacter hamburgensis X14.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: ATP + (R)-pantothenate = ADP + (R)-4'-
CC       phosphopantothenate.
CC   -!- PATHWAY: Cofactor biosynthesis; coenzyme A biosynthesis; coenzyme
CC       A from pantothenate: step 1/5.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Probable).
CC   -!- SIMILARITY: Belongs to the prokaryotic pantothenate kinase family.
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DR   EMBL; CP000319; ABE61029.1; -; Genomic_DNA.
DR   RefSeq; YP_575489.1; -.
DR   GeneID; 4029570; -.
DR   GenomeReviews; CP000319_GR; Nham_0128.
DR   KEGG; nha:Nham_0128; -.
DR   NMPDR; fig|323097.3.peg.503; -.
DR   HOGENOM; Q1QRW8; -.
DR   OMA; Q1QRW8; PKVDLIT.
DR   BioCyc; NHAM323097:NHAM_0128-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0004594; F:pantothenate kinase activity; IEA:HAMAP.
DR   GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00215; -; 1.
DR   InterPro; IPR004566; PanK_bact.
DR   PANTHER; PTHR10285:SF7; PanK_bact; 1.
DR   PIRSF; PIRSF000545; Pantothenate_kin; 1.
DR   TIGRFAMs; TIGR00554; panK_bact; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Coenzyme A biosynthesis; Complete proteome; Cytoplasm;
KW   Kinase; Nucleotide-binding; Transferase.
FT   CHAIN         1    318       Pantothenate kinase.
FT                                /FTId=PRO_1000043235.
FT   NP_BIND      96    103       ATP (Potential).
SQ   SEQUENCE   318 AA;  36280 MW;  7728A77E2D9C7DD0 CRC64;
     MDLRAEQQQY NPYRIFSRSE WAKLRDDMPM TLAADEIAAL RSMHDRLDLT EVEEIYLPLS
     RLLSIYVASM QRLFVAQRRF LGIQDRKVPY IIGVAGSVAV GKSTTARVLQ ALLARWSPGP
     KVDLITTDGF LFPNAVLERH GLMQKKGFPE SYKLPMLLAF LSDIKAGRAP VRAPVYSHLT
     YDIVPKSWIE VSQPDILIVE GVNVLQTGRL PRDGRAVPVV SDFFDFSVYL DAEEPVLRDW
     YVKRFLALRD TAFHDPRSYF HRYALLSDDE ATATAIAIWE RTNRANLEDN ILPTRPRATL
     ILKKGADHVV EQVALRRL
//