Q1QRM1 (GLND_NITHX) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
[Protein-PII] uridylyltransferase
Short name=PII uridylyl-transferase
EC=2.7.7.59

Alternative name(s):
UTase
Uridylyl-removing enzyme

Gene names

Name:	glnD
Ordered Locus Names:	Nham_0226

Organism

Nitrobacter hamburgensis (strain X14 / DSM 10229) [Complete proteome] [HAMAP]

Taxonomic identifier

323097 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Nitrobacter › Nitrobacter hamburgensis

Protein attributes

Sequence length	931 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein By similarity. HAMAP-Rule MF_00277
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP-Rule MF_00277
Sequence similarities	Belongs to the GlnD family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: EC amino acid binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 931	931	[Protein-PII] uridylyltransferase HAMAP-Rule MF_00277		PRO_1000022348

Sequences

	Sequence		Length	Mass (Da)
	Q1QRM1 [UniParc]. Last modified May 16, 2006. Version 1. Checksum: 4609DB25262D4648	FASTA	931	104,795
	10 20 30 40 50 60 MDLATTNDAA GAGNDFDTAR ITGDIDALAA KHAGHEDVFR AAVSRLLKAE LAKVRDAAQA 70 80 90 100 110 120 KLLRDRHGRR CAERLCFIQD EIIRLSFSAA TRHLYHSPIP SDGERMAVVA TGGYGRGLMA 130 140 150 160 170 180 PESDIDLLFI LPYKQTAWGE QVAEAILYCL WDMGLNVGHA TRSVNESIRQ ARRDMTVRTG 190 200 210 220 230 240 ILETRFLAGD RALYDELVTR FDTEVVQGTA AEFVTAKLAE REERHRRAGQ SRYLVEPNVK 250 260 270 280 290 300 DGKGGLRDLH TLFWIAKYVY RVHESRELLG CGVFDVREYR TFRRCADFLW SVRCNLHFAT 310 320 330 340 350 360 GRAEERLSFD LQREIAVRLG YTSHPGMQDV ERFMKHYFLT AKDVGDLTAI LCAKLEDQQA 370 380 390 400 410 420 KPAPVLGRMM SRRRPGTELR RVPEGDDFII DNNRINLAAP DVFKRDPVNL IRVFRLAQKN 430 440 450 460 470 480 NLAFHPDALR TVTRSRRLIN AQLRENPEAN RLFMEILTSN DAETVLRRMN ETGVLGHFIR 490 500 510 520 530 540 AFGKIVSMMQ FNMYHHYTVD EHLLRCIGIL QDIERGGNDE LALASELMRK IHPEHRPVIY 550 560 570 580 590 600 ITTLLHDIAK GRPEDHSIAG ARVARRLCPR LGFNASDTEL IAWLIEQHLT MSKVAQSRDL 610 620 630 640 650 660 SDRKTIENFA AVVQSVEQMK LLTILTTADI RGVGPGVWNG WKAQLLRTLY YETEPVLTGG 670 680 690 700 710 720 FSEVNRVQRI AEAQAEFRAA FTEWSEPELN AYIARHYPAY WLKVDLAHKI RHARFLRASE 730 740 750 760 770 780 QGGRKLNINV GFDEARGVTE LTIFAADHPW LLSIIAGACA SAGANIVDAQ IYTTTDGQAL 790 800 810 820 830 840 DTIAISREYD RDEDEGRRAA RIGEIIEQVI DGRLRLPDVV ARRAAGKTRL RPFVVEPKVI 850 860 870 880 890 900 VNNQWSDRHT VIEVSGLDRP GLLFQLTAAI SKLNLNIASA HVATFGERAR DVFYVTDLLG 910 920 930 ARITAPTRQA AIKRALIHLL ANGGAAEQSV G

References

[1]

"Complete sequence of chromosome of Nitrobacter hamburgensis X14." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Ivanova N., Ward B., Arp D., Klotz M., Stein L., O'Mullan G., Starkenburg S., Sayavedra L., Poret-Peterson A.T., Gentry M.E., Bruce D., Richardson P. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: X14 / DSM 10229.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000319 Genomic DNA. Translation: ABE61126.1.
RefSeq	YP_575586.1. NC_007964.1.
3D structure databases
ProteinModelPortal	Q1QRM1.
ModBase	Search...
Protein-protein interaction databases
STRING	323097.Nham_0226.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABE61126; ABE61126; Nham_0226.
GeneID	4030820.
KEGG	nha:Nham_0226.
PATRIC	22687799. VBINitHam61822_0939.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2844.
HOGENOM	HOG000261779.
KO	K00990.
OMA	SPKVWNA.
ProtClustDB	PRK05092.
Enzyme and pathway databases
BioCyc	NHAM323097:GHP7-230-MONOMER.
Family and domain databases
Gene3D	1.10.3210.10. 1 hit.
HAMAP	MF_00277. PII_uridylyl-transf.
InterPro	IPR002912. ACT_dom. IPR010043. GlnD_Uridyltrans. IPR003607. HD/PDEase_dom. IPR006674. HD_domain. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
PANTHER	PTHR13734:SF1. PTHR13734:SF1. 1 hit.
Pfam	PF01842. ACT. 2 hits. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLND_NITHX

Accession

Primary (citable) accession number: Q1QRM1

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	May 16, 2006
Last modified:	May 29, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program