Reviewed, UniProtKB/Swiss-Prot Q1QRM1 (GLND_NITHX)

Names and origin

Protein names

Recommended name:
    [Protein-PII] uridylyltransferase
      Short name=PII uridylyl-transferase
    EC=2.7.7.59
Alternative name(s):
    Uridylyl-removing enzyme
    UTase

Gene names

Name:	glnD
Ordered Locus Names:	Nham_0226

Organism

Nitrobacter hamburgensis (strain X14 / DSM 10229) [Complete proteome] [HAMAP]

Taxonomic identifier

323097 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Nitrobacter

Protein attributes

Sequence length	931 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (glnB) regulatory protein By similarity. HAMAP MF_00277
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP MF_00277
Sequence similarities	Belongs to the glnD family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP amino acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 931	931	[Protein-PII] uridylyltransferase HAMAP MF_00277		PRO_1000022348

Sequences

	Sequence		Length	Mass (Da)
	Q1QRM1-1 [UniParc]. Last modified May 16, 2006. Version 1. Checksum: 4609DB25262D4648	FASTA	931	104,795
	10 20 30 40 50 60 MDLATTNDAA GAGNDFDTAR ITGDIDALAA KHAGHEDVFR AAVSRLLKAE LAKVRDAAQA 70 80 90 100 110 120 KLLRDRHGRR CAERLCFIQD EIIRLSFSAA TRHLYHSPIP SDGERMAVVA TGGYGRGLMA 130 140 150 160 170 180 PESDIDLLFI LPYKQTAWGE QVAEAILYCL WDMGLNVGHA TRSVNESIRQ ARRDMTVRTG 190 200 210 220 230 240 ILETRFLAGD RALYDELVTR FDTEVVQGTA AEFVTAKLAE REERHRRAGQ SRYLVEPNVK 250 260 270 280 290 300 DGKGGLRDLH TLFWIAKYVY RVHESRELLG CGVFDVREYR TFRRCADFLW SVRCNLHFAT 310 320 330 340 350 360 GRAEERLSFD LQREIAVRLG YTSHPGMQDV ERFMKHYFLT AKDVGDLTAI LCAKLEDQQA 370 380 390 400 410 420 KPAPVLGRMM SRRRPGTELR RVPEGDDFII DNNRINLAAP DVFKRDPVNL IRVFRLAQKN 430 440 450 460 470 480 NLAFHPDALR TVTRSRRLIN AQLRENPEAN RLFMEILTSN DAETVLRRMN ETGVLGHFIR 490 500 510 520 530 540 AFGKIVSMMQ FNMYHHYTVD EHLLRCIGIL QDIERGGNDE LALASELMRK IHPEHRPVIY 550 560 570 580 590 600 ITTLLHDIAK GRPEDHSIAG ARVARRLCPR LGFNASDTEL IAWLIEQHLT MSKVAQSRDL 610 620 630 640 650 660 SDRKTIENFA AVVQSVEQMK LLTILTTADI RGVGPGVWNG WKAQLLRTLY YETEPVLTGG 670 680 690 700 710 720 FSEVNRVQRI AEAQAEFRAA FTEWSEPELN AYIARHYPAY WLKVDLAHKI RHARFLRASE 730 740 750 760 770 780 QGGRKLNINV GFDEARGVTE LTIFAADHPW LLSIIAGACA SAGANIVDAQ IYTTTDGQAL 790 800 810 820 830 840 DTIAISREYD RDEDEGRRAA RIGEIIEQVI DGRLRLPDVV ARRAAGKTRL RPFVVEPKVI 850 860 870 880 890 900 VNNQWSDRHT VIEVSGLDRP GLLFQLTAAI SKLNLNIASA HVATFGERAR DVFYVTDLLG 910 920 930 ARITAPTRQA AIKRALIHLL ANGGAAEQSV G

References

[1]

"Complete sequence of chromosome of Nitrobacter hamburgensis X14." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Ivanova N., Ward B., Arp D., Klotz M., Stein L., O'Mullan G., Starkenburg S., Sayavedra L., Poret-Peterson A.T., Gentry M.E., Bruce D., Richardson P. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000319 Genomic DNA. Translation: ABE61126.1.
RefSeq	YP_575586.1.
3D structure databases
SMR	Q1QRM1. Positions 71-346, 390-580, 400-643, 741-921.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1QRM1.
Genome annotation databases
GeneID	4030820.
GenomeReviews	Gene locus Nham_0226 in contig CP000319_GR.
KEGG	nha:Nham_0226.
NMPDR	fig|323097.3.peg.666.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2844.
HOGENOM	HBG687872.
OMA	MQHDLFH.
PhylomeDB	Q1QRM1.
Enzyme and pathway databases
BioCyc	NHAM323097:NHAM_0226-MONOMER.
Family and domain databases
HAMAP	MF_00277. PII_uridylyl-transf. [Tree]
InterPro	IPR002912. ACT_bd. IPR010043. GlnD_Uridyltrans. IPR003607. Metal-dep_PHydrolase_HD_dom. IPR006674. Metal-dep_PHydrolase_HD_sub. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
PANTHER	PTHR13734:SF1. GlnD_Uridyltrans. 1 hit.
Pfam	PF01842. ACT. 2 hits. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLND_NITHX

Accession

Primary (citable) accession number: Q1QRM1

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	May 16, 2006
Last modified:	February 9, 2010
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)