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Q1QQP9 (Q1QQP9_NITHX) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetyl-coenzyme A synthetase HAMAP MF_01123
EC=6.2.1.1 HAMAP MF_01123
Alternative name(s):
Acetate--CoA ligase HAMAP MF_01123
Acyl-activating enzyme HAMAP MF_01123
Gene names
Name:acsA HAMAP MF_01123
Ordered Locus Names:Nham_0558
OrganismNitrobacter hamburgensis (strain X14 / DSM 10229) [Complete proteome] [HAMAP]
Taxonomic identifier323097 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Nitrobacter

Protein attributes

Sequence length652 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA. HAMAP MF_01123

Post-translational modification

Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme By similarity. HAMAP MF_01123

Sequence similarities

Belongs to the ATP-dependent AMP-binding enzyme family. HAMAP MF_01123

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site5151 By similarity HAMAP MF_01123

Amino acid modifications

Modified residue6071N6-acetyllysine By similarity HAMAP MF_01123

Sequences

Sequence LengthMass (Da)Tools
Q1QQP9 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: 3A204089D496EDA2

FASTA65272,383
        10         20         30         40         50         60 
MSDKIYDVSA DWAKRAWVDD AKYHEMYARS IKDPNGFWSE AAKRVDWITP FTKVENTSFE 

        70         80         90        100        110        120 
LGKVSIKWFE DGVLNAAYNC IDRHLEERGD QTAIIWEGDD PSQSRHISYR ELHDEVCKMA 

       130        140        150        160        170        180 
NILRLRNVKK GDRVTIYLPM IPEAAYAILA CARIGAIHSV VFGGFSPDSI AGRLRDCKSR 

       190        200        210        220        230        240 
VVITSDEGLR GGRTIAMKAN VDTAIEKVNG EVDWVIVVKR TGGKVNMNPT RDVWYHEAAA 

       250        260        270        280        290        300 
VVESECPCEP MHAEDPLFIL YTSGSTGQPK GVLHTTAGYL IFVAMTHQYV FDYHDGDIYW 

       310        320        330        340        350        360 
CTADVGWVTG HSYILYGPLC NGATTMMFEG VPNYPDNSRF WNVIDKHKVN IFYTAPTAIR 

       370        380        390        400        410        420 
ALMQGGDDPV KKTSRASLRL LGSVGEPINP EAWEWYHRVV GDGRCPVVDT WWQTETGGIM 

       430        440        450        460        470        480 
ISPLPGAIAQ KPGSATRPFF GIVPEIVDAD GKVLEGECSG NLCIARSWPA QVRTVYGDHA 

       490        500        510        520        530        540 
RFEQTYFSSY KGKYFSGDGC RRDADGYYWI TGRVDDVINV SGHRMGTAEV ESSLVAHESV 

       550        560        570        580        590        600 
SEAAVVGYPH NIKGQGIYAY VTLMQGVEPS ETLRKELVAW VRKDIGPIAS PDLIQFAPGL 

       610        620        630        640        650 
PKTRSGKIMR RILRKIAEDE PSSLGDTTTL ADPGVVTDLV KNRQNKKDGA VA

« Hide

References

[1]"Complete sequence of chromosome of Nitrobacter hamburgensis X14."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Ivanova N., Ward B., Arp D., Klotz M., Stein L., O'Mullan G., Starkenburg S., Sayavedra L., Poret-Peterson A.T., Gentry M.E., Bruce D., Richardson P.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: X14 / DSM 10229.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000319 Genomic DNA. Translation: ABE61448.1.
RefSeqYP_575908.1. NC_007964.1.

3D structure databases

ProteinModelPortalQ1QQP9.
SMRQ1QQP9. Positions 8-644.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ1QQP9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4031306.
GenomeReviewsGene locus Nham_0558 in contig CP000319_GR.
KEGGnha:Nham_0558.
NMPDRfig|323097.3.peg.155.
PATRIC22688531. VBINitHam61822_1302.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0365.
HOGENOMHBG547964.
OMATRGTEES.
PhylomeDBQ1QQP9.
ProtClustDBPRK00174.

Family and domain databases

HAMAPMF_01123. Ac_CoA_synth.
[Tree]
InterProIPR011904. Ac_CoA_lig.
IPR024597. Acyl-CoA_synth_DUF3448.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
KOK01895.
PANTHERPTHR24095:SF42. PTHR24095:SF42. 1 hit.
PfamPF00501. AMP-binding. 1 hit.
PF11930. DUF3448. 1 hit.
[Graphical view]
TIGRFAMsTIGR02188. Ac_CoA_lig_AcsA. 1 hit.
PROSITEPS00455. AMP_BINDING. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ1QQP9_NITHX
AccessionPrimary (citable) accession number: Q1QQP9
Entry history
Integrated into UniProtKB/TrEMBL: May 16, 2006
Last sequence update: May 16, 2006
Last modified: December 14, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info