Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glutamine--tRNA ligase

Gene

glnS

Organism
Nitrobacter hamburgensis (strain DSM 10229 / NCIMB 13809 / X14)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei69L-glutamineUniRule annotation1
Binding sitei214L-glutamineUniRule annotation1
Binding sitei233ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi37 – 39ATPUniRule annotation3
Nucleotide bindingi43 – 49ATPUniRule annotation7
Nucleotide bindingi263 – 264ATPUniRule annotation2
Nucleotide bindingi271 – 273ATPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--tRNA ligaseUniRule annotation (EC:6.1.1.18UniRule annotation)
Alternative name(s):
Glutaminyl-tRNA synthetaseUniRule annotation
Short name:
GlnRSUniRule annotation
Gene namesi
Name:glnSUniRule annotation
Ordered Locus Names:Nham_1710
OrganismiNitrobacter hamburgensis (strain DSM 10229 / NCIMB 13809 / X14)
Taxonomic identifieri323097 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeNitrobacter
Proteomesi
  • UP000001953 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000954941 – 558Glutamine--tRNA ligaseAdd BLAST558

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi323097.Nham_1710.

Structurei

3D structure databases

ProteinModelPortaliQ1QMM1.
SMRiQ1QMM1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi36 – 46"HIGH" regionUniRule annotationAdd BLAST11
Motifi270 – 274"KMSKS" regionUniRule annotation5

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CX6. Bacteria.
COG0008. LUCA.
HOGENOMiHOG000259232.
KOiK01886.
OMAiVTHSICT.
OrthoDBiPOG091H00G9.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 3 hits.
HAMAPiMF_00126. Gln_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_N.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
PfamiView protein in Pfam
PF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00440. glnS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1QMM1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDESTADAG RDFIRDIVAA DLASGKHKSV VTRFPPEPNG YLHLGHAKSI
60 70 80 90 100
CLNFGIAEEF GGCCHLRFDD TNPTKEEQEY IDAIQRDVRW LGFDWGKNLH
110 120 130 140 150
YASDYFEQLY AWAQHLVRAG KAYVDDQSQE DIRLARGTLT EPGRDSPFRD
160 170 180 190 200
RPVDENLDLF ARMRAGEFPN GARVLRARID MASGNINLRD PVLYRILHAP
210 220 230 240 250
HPRTGTAWNI YPSYDFAHGQ SDSIEHITHS ICTLEFEDHR PLYDWFLDNL
260 270 280 290 300
PVPSRPHQYE FARLNVTHTL LSKRILTELV RGGHVAGWDD PRMPTLAGLQ
310 320 330 340 350
RRGVPAEALR EFIKRIGVAK ANSTVDVGML DFAIRETLNK SAPRRMAVLR
360 370 380 390 400
PLKIVIENYP EGESEELEAV NHPDDPSRGT RRIRFGRELY IEQDDFMENP
410 420 430 440 450
PKKFFRLSPG REVRLRYAYF VTCREVVKNA AGDVVELRCT YDPATKGGNA
460 470 480 490 500
PDGRKVKATM HWVSAAEAVP AEIRLYGHLF ATAQPDAANF ASELNPQSLE
510 520 530 540 550
TLSGMVEPAL ARDDTDGAVQ FERQGYFCRD RDSSPGRLVF NRTVGLRDTW

AKVAAAGS
Length:558
Mass (Da):63,038
Last modified:May 16, 2006 - v1
Checksum:i7D76EAEF0A412495
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000319 Genomic DNA. Translation: ABE62526.1.
RefSeqiWP_011510208.1. NC_007964.1.

Genome annotation databases

EnsemblBacteriaiABE62526; ABE62526; Nham_1710.
KEGGinha:Nham_1710.

Similar proteinsi

Entry informationi

Entry nameiSYQ_NITHX
AccessioniPrimary (citable) accession number: Q1QMM1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: May 16, 2006
Last modified: November 22, 2017
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families