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Q1QMM1 (SYQ_NITHX) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamine--tRNA ligase

EC=6.1.1.18
Alternative name(s):
Glutaminyl-tRNA synthetase
Short name=GlnRS
Gene names
Name:glnS
Ordered Locus Names:Nham_1710
OrganismNitrobacter hamburgensis (strain X14 / DSM 10229) [Complete proteome] [HAMAP]
Taxonomic identifier323097 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeNitrobacter

Protein attributes

Sequence length558 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln). HAMAP-Rule MF_00126

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00126

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00126.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutaminyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

glutamyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glutamine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 558558Glutamine--tRNA ligase HAMAP-Rule MF_00126
PRO_1000095494

Regions

Motif36 – 4611"HIGH" region HAMAP-Rule MF_00126
Motif270 – 2745"KMSKS" region HAMAP-Rule MF_00126

Sites

Binding site2731ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q1QMM1 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: 7D76EAEF0A412495

FASTA55863,038
        10         20         30         40         50         60 
MTDESTADAG RDFIRDIVAA DLASGKHKSV VTRFPPEPNG YLHLGHAKSI CLNFGIAEEF 

        70         80         90        100        110        120 
GGCCHLRFDD TNPTKEEQEY IDAIQRDVRW LGFDWGKNLH YASDYFEQLY AWAQHLVRAG 

       130        140        150        160        170        180 
KAYVDDQSQE DIRLARGTLT EPGRDSPFRD RPVDENLDLF ARMRAGEFPN GARVLRARID 

       190        200        210        220        230        240 
MASGNINLRD PVLYRILHAP HPRTGTAWNI YPSYDFAHGQ SDSIEHITHS ICTLEFEDHR 

       250        260        270        280        290        300 
PLYDWFLDNL PVPSRPHQYE FARLNVTHTL LSKRILTELV RGGHVAGWDD PRMPTLAGLQ 

       310        320        330        340        350        360 
RRGVPAEALR EFIKRIGVAK ANSTVDVGML DFAIRETLNK SAPRRMAVLR PLKIVIENYP 

       370        380        390        400        410        420 
EGESEELEAV NHPDDPSRGT RRIRFGRELY IEQDDFMENP PKKFFRLSPG REVRLRYAYF 

       430        440        450        460        470        480 
VTCREVVKNA AGDVVELRCT YDPATKGGNA PDGRKVKATM HWVSAAEAVP AEIRLYGHLF 

       490        500        510        520        530        540 
ATAQPDAANF ASELNPQSLE TLSGMVEPAL ARDDTDGAVQ FERQGYFCRD RDSSPGRLVF 

       550 
NRTVGLRDTW AKVAAAGS 

« Hide

References

[1]"Complete sequence of chromosome of Nitrobacter hamburgensis X14."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Ivanova N., Ward B., Arp D., Klotz M., Stein L., O'Mullan G., Starkenburg S., Sayavedra L., Poret-Peterson A.T., Gentry M.E., Bruce D., Richardson P.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: X14 / DSM 10229.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000319 Genomic DNA. Translation: ABE62526.1.
RefSeqYP_576986.1. NC_007964.1.

3D structure databases

ProteinModelPortalQ1QMM1.
SMRQ1QMM1. Positions 12-549.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING323097.Nham_1710.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE62526; ABE62526; Nham_1710.
GeneID4030310.
KEGGnha:Nham_1710.
PATRIC22691084. VBINitHam61822_2564.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0008.
HOGENOMHOG000259232.
KOK01886.
OMAKSDSWID.
OrthoDBEOG6DRPF7.

Enzyme and pathway databases

BioCycNHAM323097:GHP7-1737-MONOMER.

Family and domain databases

Gene3D1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPMF_00126. Gln_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERPTHR10119. PTHR10119. 1 hit.
PfamPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSPR00987. TRNASYNTHGLU.
SUPFAMSSF50715. SSF50715. 1 hit.
TIGRFAMsTIGR00440. glnS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYQ_NITHX
AccessionPrimary (citable) accession number: Q1QMM1
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: May 16, 2006
Last modified: May 14, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries