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Q1QMJ3 (KDSA_NITHX) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
2-dehydro-3-deoxyphosphooctonate aldolase
EC=2.5.1.55
Alternative name(s):
3-deoxy-D-manno-octulosonic acid 8-phosphate synthase
KDO-8-phosphate synthase
Short name=KDO 8-P synthase
Short name=KDOPS
Phospho-2-dehydro-3-deoxyoctonate aldolase
Gene names
Name:kdsA
Ordered Locus Names:Nham_1739
OrganismNitrobacter hamburgensis (strain X14 / DSM 10229) [Complete proteome] [HAMAP]
Taxonomic identifier323097 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Nitrobacter

Protein attributes

Sequence length287 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + D-arabinose 5-phosphate + H2O = 2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate. HAMAP MF_00056

Pathway

Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate: step 2/3. HAMAP MF_00056

Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis. HAMAP MF_00056

Subcellular location

Cytoplasm By similarity HAMAP MF_00056.

Sequence similarities

Belongs to the KdsA family.

Ontologies

Keywords
   Biological processLipopolysaccharide biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processlipopolysaccharide biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-deoxy-8-phosphooctulonate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2872872-dehydro-3-deoxyphosphooctonate aldolase HAMAP MF_00056
PRO_0000304462

Sequences

Sequence LengthMass (Da)Tools
Q1QMJ3 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: 0CE2269C3320F917

FASTA28729,681
        10         20         30         40         50         60 
MNQSVSAAPV VSAGSVTFGQ DRPLSIIAGP CQMESRAHAL EVAGALKEIA ARLNIGLVFK 

        70         80         90        100        110        120 
TSFDKANRTS ASGARGLGLK QALPVFAEIG SSLGLPVLTD VHEAAQCTEV AQAVDVLQIP 

       130        140        150        160        170        180 
AFLCRQTDLL LAAAATGKVV NVKKGQFLAP WDMANVVAKI TGGGNPNVLV TERGASFGYN 

       190        200        210        220        230        240 
TLVSDMRSLP ILARTTGAPV IFDATHSVQQ PGGNGTSSGG EREFVPVLAR AAVAVGVAGV 

       250        260        270        280 
FIETHPDPDH APSDGPNMVP LREFEALVRR LMAFDALAKA ADPALPK

« Hide

References

[1]"Complete sequence of chromosome of Nitrobacter hamburgensis X14."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Ivanova N., Ward B., Arp D., Klotz M., Stein L., O'Mullan G., Starkenburg S., Sayavedra L., Poret-Peterson A.T., Gentry M.E., Bruce D., Richardson P.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: X14 / DSM 10229.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000319 Genomic DNA. Translation: ABE62554.1.
RefSeqYP_577014.1. NC_007964.1.

3D structure databases

HSSPHSSP built from PDB template 1VS1 based on UniProtKB Q9YEJ7.
ProteinModelPortalQ1QMJ3.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ1QMJ3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4030358.
GenomeReviewsGene locus Nham_1739 in contig CP000319_GR.
KEGGnha:Nham_1739.
NMPDRfig|323097.3.peg.2393.
PATRIC22691152. VBINitHam61822_2598.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2877.
HOGENOMHBG575990.
OMADVHEAAQ.
PhylomeDBQ1QMJ3.
ProtClustDBPRK05198.

Enzyme and pathway databases

BioCycNHAM323097:NHAM_1739-MONOMER.

Family and domain databases

HAMAPMF_00056. KDO8P_synth.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR006218. DAHP1/KDSA.
IPR006269. KDO8P_synthase.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01627.
PANTHERPTHR21057:SF2. KDO8P_synthase. 1 hit.
PfamPF00793. DAHP_synth_1. 1 hit.
[Graphical view]
TIGRFAMsTIGR01362. KDO8P_synth. 1 hit.
ProtoNetSearch...

Entry information

Entry nameKDSA_NITHX
AccessionPrimary (citable) accession number: Q1QMJ3
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: May 16, 2006
Last modified: January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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