Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q1QM39 (TYPH_NITHX) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative thymidine phosphorylase

EC=2.4.2.4
Alternative name(s):
TdRPase
Gene names
Ordered Locus Names:Nham_1900
OrganismNitrobacter hamburgensis (strain X14 / DSM 10229) [Complete proteome] [HAMAP]
Taxonomic identifier323097 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeNitrobacter

Protein attributes

Sequence length510 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate. HAMAP-Rule MF_00703

Sequence similarities

Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

Sequence caution

The sequence ABE62708.1 differs from that shown. Reason: Erroneous initiation.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 510510Putative thymidine phosphorylase HAMAP-Rule MF_00703
PRO_0000314704

Sequences

Sequence LengthMass (Da)Tools
Q1QM39 [UniParc].

Last modified January 15, 2008. Version 2.
Checksum: 787647AD246C0489

FASTA51054,756
        10         20         30         40         50         60 
MNGTDLPRLQ PKIRRVNLDT GRENVVVISR HSAALRPEIF RGFSRVELRR NAKIMLATLI 

        70         80         90        100        110        120 
ITDDDSLVGP DDLGLSEPAF RRFAEPVGSA VTIAPAASPA SLDAVRAKIM GQTFSAVDIS 

       130        140        150        160        170        180 
AIIDDLTHYR YSDMEIAAFL ISSASFMTNG ELIALVDSMA RAGTQLKWRN PIIVDKHCIG 

       190        200        210        220        230        240 
GIPGNRTSMI VVPIVAAHGL TIPKTSSRAI TSPAGTADTM EMLARVDVGV EEMKDIVAAC 

       250        260        270        280        290        300 
RGCLVWGGHV NLSPADDILI SVERPLGLDT REQMVASILS KKLAAGSTHL LIDLPVGPTA 

       310        320        330        340        350        360 
KLVNEMEAMR LRKLFEFVGD HYGISVEVVV TDGRQPIGNG IGPVLEAQDV MAVLANDPEA 

       370        380        390        400        410        420 
PADLREKSLR LAAHLLEYDP KLRGGSGYAR ARELLDSGAA LKQMQKIIDA QGPPTCCTDL 

       430        440        450        460        470        480 
GNLTFDVTAS RDGFVSGINC LQLNRLARIA GAPIDKGAGI RLFKKIGDRV QQGEPLYRIH 

       490        500        510 
AFERSGRDLA AAGTTAYTID SEESNLEATP 

« Hide

References

[1]"Complete sequence of chromosome of Nitrobacter hamburgensis X14."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Ivanova N., Ward B., Arp D., Klotz M., Stein L., O'Mullan G., Starkenburg S., Sayavedra L., Poret-Peterson A.T., Gentry M.E., Bruce D., Richardson P.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: X14 / DSM 10229.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000319 Genomic DNA. Translation: ABE62708.1. Different initiation.
RefSeqYP_577168.1. NC_007964.1.

3D structure databases

ProteinModelPortalQ1QM39.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING323097.Nham_1900.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE62708; ABE62708; Nham_1900.
GeneID4033038.
KEGGnha:Nham_1900.
PATRIC22691488. VBINitHam61822_2764.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0213.
HOGENOMHOG000252767.
KOK00758.
OrthoDBEOG61ZTGG.

Enzyme and pathway databases

BioCycNHAM323097:GHP7-1929-MONOMER.

Family and domain databases

Gene3D3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPMF_00703. Thymid_phosp_2.
InterProIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view]
PANTHERPTHR10515. PTHR10515. 1 hit.
PfamPF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
PIRSFPIRSF000478. TP_PyNP. 1 hit.
SMARTSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsTIGR02645. ARCH_P_rylase. 1 hit.
PROSITEPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTYPH_NITHX
AccessionPrimary (citable) accession number: Q1QM39
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 15, 2008
Last modified: May 14, 2014
This is version 52 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families