Q1QK02 (Q1QK02_NITHX) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase 1 HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE2-1 HAMAP MF_01902
Ordered Locus Names:	Nham_2666

Organism

Nitrobacter hamburgensis (strain X14 / DSM 10229) [Complete proteome] [HAMAP]

Taxonomic identifier

323097 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Nitrobacter

Protein attributes

Sequence length	1164 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS004013 DNA replication HAMAP MF_01902 SAAS SAAS004013
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q1QK02 [UniParc]. Last modified May 16, 2006. Version 1. Checksum: B59AD5B857EE225C	FASTA	1,164	131,862
	10 20 30 40 50 60 MKHPRDIPSY AEIGIATNFS FLHGASHPQE YVHQASELRL PIIGIADRNT LAGVVRAYAE 70 80 90 100 110 120 LGNPELRSKP RLLIGSRLVF IDGTPDILVY PRDRDAYGRL CRLLTRGKRA AEKGECHLGL 130 140 150 160 170 180 DDLLEFSEGQ LLVLTLPHRF DTTTALKVLD RLRQSRAAGV WLAASLLYRG DDRRRLLRLR 190 200 210 220 230 240 RIATAARVPL LATNEVLYHH PARRPLQDVL TCIREKATVH AIGRKLEANA ERYLKPTDEM 250 260 270 280 290 300 ARLFRDIPEA IAETVTLASR IAFTLDQLKY QYPDEPVPPG KTAQRRLEDL TWAGAHKYFP 310 320 330 340 350 360 VRIPPKTRKV LHKELRLIRQ LNYAHYFLTV HDIVHWARSR NILCQGRGSA ANSAVCYVLG 370 380 390 400 410 420 ITAVNPAETD LLFERFISKE RLEPPDIDVD FEHSRREEVM QYVYRRYGRH RAAIIATVIH 430 440 450 460 470 480 YRPRSAIRDV GKALGLTEDV TAALADTVWG SWGDGVSDMQ VRQAGFDPRN PMLRRAVALA 490 500 510 520 530 540 TELIGFPRHL SQHVGGYVLT QDRLDTYVPI GNAAMDDRTF IEWDKDDVDA LRMMKVDVLA 550 560 570 580 590 600 LGMLTCIRKC FDLIARHKGK RWELATVPRE QREVYDMLCK GESLGVFQVE SRAQMNMLPR 610 620 630 640 650 660 LKPRTFYDLV IEVAIVRPGP IQGDMVHPYL KRRAMKPEDI DYPYPKGGDR NELRNVLHKT 670 680 690 700 710 720 LGVPLFQEQA MRIAIEAAKF TSQEANGLRR AMATFRNVGT IGTFQEKMVN SMIARGYDPV 730 740 750 760 770 780 FAKNCFEQIK GFGSYGFPES HAASFAQLVY VSSWLKRFHP DAFCCGLLNS QPMGFYAPAQ 790 800 810 820 830 840 IVGDARKNGV AVRPIDVSFS YSQNTLEERA GRHYAMRLGF RQIDGFKWVD KDEAKLKQDQ 850 860 870 880 890 900 AKHLSSASSP RTRGPITPVL NEFSTHVSGH SERLALSQAE RSKGPHVRGD DETLCAGDWG 910 920 930 940 950 960 ERIVAARQRR PFTSIEDFAR DTKLPKRALI LLADADAFRS LGLDRRAALW AVRRLPDDVP 970 980 990 1000 1010 1020 LPLFESAIAR ELPDERAAPL PQMPLPEQVV ADYQTVRLSL KGHPMEFLRT MLTRERVVSC 1030 1040 1050 1060 1070 1080 AEVCHANDKR RVRCAGVVLV RQRPGSAKGV VFMTLEDETG IANIVVWPNI MARYRKEVMG 1090 1100 1110 1120 1130 1140 ARLIEVEGTI QSSPEQVVHL VASKLTDRST ELMHLANDAL VSRYPLPPPA APLDDDRRDH 1150 1160 PDNPAQRVRH PRNVRILPRS RDFH

References

[1]

"Complete sequence of chromosome of Nitrobacter hamburgensis X14." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Ivanova N., Ward B., Arp D., Klotz M., Stein L., O'Mullan G., Starkenburg S., Sayavedra L., Poret-Peterson A.T., Gentry M.E., Bruce D., Richardson P. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: X14 / DSM 10229.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000319 Genomic DNA. Translation: ABE63445.1.
RefSeq	YP_577905.1. NC_007964.1.
3D structure databases
ProteinModelPortal	Q1QK02.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1QK02.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4032440.
GenomeReviews	Gene locus Nham_2666 in contig CP000319_GR.
KEGG	nha:Nham_2666.
NMPDR	fig|323097.3.peg.2951.
PATRIC	22693201. VBINitHam61822_3605.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0587.
HOGENOM	HBG734490.
OMA	LATNRNG.
ProtClustDB	PRK05672.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR012340. NA-bd_OB-fold. IPR016027. NA-bd_OB-fold-like. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR004805. PolC_alpha. [Graphical view]
Gene3D	G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q1QK02_NITHX

Accession

Primary (citable) accession number: Q1QK02

Entry history

Integrated into UniProtKB/TrEMBL:	May 16, 2006
Last sequence update:	May 16, 2006
Last modified:	December 14, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)