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Q1QI14 (PNCB_NITHX) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:Nham_3403
OrganismNitrobacter hamburgensis (strain X14 / DSM 10229) [Complete proteome] [HAMAP]
Taxonomic identifier323097 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeNitrobacter

Protein attributes

Sequence length434 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 434434Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_1000146845

Sequences

Sequence LengthMass (Da)Tools
Q1QI14 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: FDBECF475836DB1F

FASTA43449,559
        10         20         30         40         50         60 
MTVTDIATRT YNHGWRLDPI VRSLLDTDFY KLLMLQMIRE FYPNEHVTFS VINRSRHVRL 

        70         80         90        100        110        120 
AEAIDEGELR AQLDHARSIR FSKNELIWLA GNTFYGKTQM FSPDFIDWLA TFRLGEYELR 

       130        140        150        160        170        180 
KVDGQYELHF HGPWTHTTMW EIPALAILNE LRSRQVTKGQ GRFALDVLYA RAKAKLWAKV 

       190        200        210        220        230        240 
ERLRKLDDLW LSDFGTRRRH GFLWQRWCVE AAKEGLGPAF TGTSNVLLAM DNDLEAIGTN 

       250        260        270        280        290        300 
AHELPMVAAA LADDDTALRR APYRILDQWR HTYGGNLLVA LPDAFGTQAF LRDAPEWVAD 

       310        320        330        340        350        360 
WTGFRPDSLP PIAAGEEIIK WWKQKSRDPR EKLLVFSDGM DVDSIEETYH HFAGRVRVSF 

       370        380        390        400        410        420 
GWGTNLTNDF VGCSPDGTVD LDPISIVCKV TSVNGRPAVK LSDNPEKATG EPSEIERYLR 

       430 
VFGSAGRVRA PVHV 

« Hide

References

[1]"Complete sequence of chromosome of Nitrobacter hamburgensis X14."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Ivanova N., Ward B., Arp D., Klotz M., Stein L., O'Mullan G., Starkenburg S., Sayavedra L., Poret-Peterson A.T., Gentry M.E., Bruce D., Richardson P.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: X14 / DSM 10229.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000319 Genomic DNA. Translation: ABE64133.1.
RefSeqYP_578593.1. NC_007964.1.

3D structure databases

ProteinModelPortalQ1QI14.
SMRQ1QI14. Positions 1-423.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING323097.Nham_3403.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE64133; ABE64133; Nham_3403.
GeneID4033226.
KEGGnha:Nham_3403.
PATRIC22694825. VBINitHam61822_4409.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284929.
KOK00763.
OMAKLTMQCA.
OrthoDBEOG6X10XB.
ProtClustDBPRK05321.

Enzyme and pathway databases

BioCycNHAM323097:GHP7-3457-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERPTHR11098:SF1. PTHR11098:SF1. 1 hit.
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_NITHX
AccessionPrimary (citable) accession number: Q1QI14
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 16, 2006
Last modified: March 19, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways