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Protein

Superoxide dismutase [Cu-Zn]

Gene

Nham_3597

Organism
Nitrobacter hamburgensis (strain DSM 10229 / NCIMB 13809 / X14)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • Cu cationUniRule annotationNote: Binds 1 copper ion per subunit.UniRule annotation
  • Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Ligandi

CopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Nham_3597Imported
OrganismiNitrobacter hamburgensis (strain DSM 10229 / NCIMB 13809 / X14)Imported
Taxonomic identifieri323097 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeNitrobacter
Proteomesi
  • UP000001953 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_500419585423 – 169Superoxide dismutase [Cu-Zn]Sequence analysisAdd BLAST147

Interactioni

Protein-protein interaction databases

STRINGi323097.Nham_3597.

Structurei

3D structure databases

ProteinModelPortaliQ1QHH2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini36 – 168Sod_CuInterPro annotationAdd BLAST133

Sequence similaritiesi

Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4108Z7T. Bacteria.
COG2032. LUCA.
HOGENOMiHOG000263448.
KOiK04565.
OMAiAFHVHET.
OrthoDBiPOG091H05EB.

Family and domain databases

CDDicd00305. Cu-Zn_Superoxide_Dismutase. 1 hit.
Gene3Di2.60.40.200. 1 hit.
InterProiIPR024134. SOD_Cu/Zn_/chaperone.
IPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PANTHERiPTHR10003. PTHR10003. 1 hit.
PfamiPF00080. Sod_Cu. 1 hit.
[Graphical view]
PRINTSiPR00068. CUZNDISMTASE.
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiPS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1QHH2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIARILLTAT TLLVLTVTTA SASSARATLK NAEGVDVGGV ELIQADDGVL
60 70 80 90 100
LKVALKGLPP GDHAFHIHAV GKCEPPFTSA GGHFNPGDKK HGMMAADGHH
110 120 130 140 150
AGDMPNLIVP ASGELKLEVV NTAITLDKDK PNSVLKPGGT AVVVHAAADD
160
YKTDPTGDAG GRIACGVIE
Length:169
Mass (Da):17,185
Last modified:May 16, 2006 - v1
Checksum:i59FC61AD0B496CEE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000319 Genomic DNA. Translation: ABE64325.1.
RefSeqiWP_011511966.1. NC_007964.1.

Genome annotation databases

EnsemblBacteriaiABE64325; ABE64325; Nham_3597.
KEGGinha:Nham_3597.
PATRICi22695257. VBINitHam61822_4623.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000319 Genomic DNA. Translation: ABE64325.1.
RefSeqiWP_011511966.1. NC_007964.1.

3D structure databases

ProteinModelPortaliQ1QHH2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi323097.Nham_3597.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABE64325; ABE64325; Nham_3597.
KEGGinha:Nham_3597.
PATRICi22695257. VBINitHam61822_4623.

Phylogenomic databases

eggNOGiENOG4108Z7T. Bacteria.
COG2032. LUCA.
HOGENOMiHOG000263448.
KOiK04565.
OMAiAFHVHET.
OrthoDBiPOG091H05EB.

Family and domain databases

CDDicd00305. Cu-Zn_Superoxide_Dismutase. 1 hit.
Gene3Di2.60.40.200. 1 hit.
InterProiIPR024134. SOD_Cu/Zn_/chaperone.
IPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PANTHERiPTHR10003. PTHR10003. 1 hit.
PfamiPF00080. Sod_Cu. 1 hit.
[Graphical view]
PRINTSiPR00068. CUZNDISMTASE.
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiPS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ1QHH2_NITHX
AccessioniPrimary (citable) accession number: Q1QHH2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 16, 2006
Last sequence update: May 16, 2006
Last modified: November 2, 2016
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.