Q1QHE0 (PHS_NITHX) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative pterin-4-alpha-carbinolamine dehydratase
Short name=PHS
EC=4.2.1.96

Alternative name(s):
4-alpha-hydroxy-tetrahydropterin dehydratase
Pterin carbinolamine dehydratase
Short name=PCD

Gene names

Ordered Locus Names:

Nham_3629

Organism

Nitrobacter hamburgensis (strain X14 / DSM 10229) [Complete proteome] [HAMAP]

Taxonomic identifier

323097 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Nitrobacter

Protein attributes

Sequence length	101 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O. HAMAP MF_00434
Sequence similarities	Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

Ontologies

Keywords
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tetrahydrobiopterin biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	4-alpha-hydroxytetrahydrobiopterin dehydratase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 101	101	Putative pterin-4-alpha-carbinolamine dehydratase HAMAP MF_00434		PRO_1000050429

Sequences

	Sequence		Length	Mass (Da)
	Q1QHE0 [UniParc]. Last modified May 16, 2006. Version 1. Checksum: D5C13288E18619AF	FASTA	101	11,219
	10 20 30 40 50 60 MAERLSEDAR KAAVKALSGW SEVAGREAIA RVFTFRDFNE AFGFMARVAL VAEKNDHHPE 70 80 90 100 WRNVYKTVEV VLATHDAGGV TERDIRLAEA MNAIARQFGV A

References

[1]

"Complete sequence of chromosome of Nitrobacter hamburgensis X14." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Ivanova N., Ward B., Arp D., Klotz M., Stein L., O'Mullan G., Starkenburg S., Sayavedra L., Poret-Peterson A.T., Gentry M.E., Bruce D., Richardson P. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: X14 / DSM 10229.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000319 Genomic DNA. Translation: ABE64357.1.
RefSeq	YP_578817.1. NC_007964.1.
3D structure databases
ProteinModelPortal	Q1QHE0.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1QHE0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4031353.
GenomeReviews	Gene locus Nham_3629 in contig CP000319_GR.
KEGG	nha:Nham_3629.
NMPDR	fig|323097.3.peg.1756.
PATRIC	22695331. VBINitHam61822_4659.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2154.
HOGENOM	HBG705804.
OMA	SEERKTR.
PhylomeDB	Q1QHE0.
ProtClustDB	PRK00823.
Enzyme and pathway databases
BioCyc	NHAM323097:NHAM_3629-MONOMER.
Family and domain databases
HAMAP	MF_00434. Pterin_4_alpha. [Tree]
InterPro	IPR001533. Trans/pterin_deHydtase. [Graphical view]
Gene3D	G3DSA:3.30.1360.20. Trans_pterinDh. 1 hit.
KO	K01724.
PANTHER	PTHR12599. Trans_pterinDh. 1 hit.
Pfam	PF01329. Pterin_4a. 1 hit. [Graphical view]
SUPFAM	SSF55248. Trans_pterinDh. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PHS_NITHX

Accession

Primary (citable) accession number: Q1QHE0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	May 16, 2006
Last modified:	January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program