Q1QH09 (Q1QH09_NITHX) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase 2 HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE2-2 HAMAP MF_01902
Ordered Locus Names:	Nham_3765

Organism

Nitrobacter hamburgensis (strain X14 / DSM 10229) [Complete proteome] [HAMAP]

Taxonomic identifier

323097 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Nitrobacter

Protein attributes

Sequence length	1087 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS004013 DNA replication HAMAP MF_01902 SAAS SAAS004013
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q1QH09 [UniParc]. Last modified May 16, 2006. Version 1. Checksum: 4E607C66617496BB	FASTA	1,087	122,129
	10 20 30 40 50 60 MTSRYAELQV TSHFSFLRGA SSCEELFAHA ASLGIEALAI VDHNSLAGIV RAHEAAKVTG 70 80 90 100 110 120 VRLIVGCRLD LADGMSVLVY PTDRPAYSRL CRLLSIGKTR GGKAKCILNW EDVVDWSEGL 130 140 150 160 170 180 IAALVPDVAD DACAQRIRRL RDTFGDRAHM ALTLRRRPND QMRIHELNNM AQRFRVATVV 190 200 210 220 230 240 TNDVLFHEPA RRILQDVVTC IRHNVTIDEA GFRRERHADR YLKPPDEMTR LFARYPEALA 250 260 270 280 290 300 RTVAIAGRCT FSMDELAYQY PEERTMPGLT PQQALEKLTW EGAAERYPEG LPDEVRPTLE 310 320 330 340 350 360 HELRLIERLQ YAPYFLTVNS IVRFARSRDI LCQGRGSAAN SAVCYVLGIT SIDPERNDLL 370 380 390 400 410 420 FERFVSEERR EPPDIDVDFE HERREIVMQW VFETYGRNHA ALCSTVIRYR AKGALRDVGK 430 440 450 460 470 480 ALGLTEDLIK LLSSQIWGWS EEGVEPKHAE ELNLNLDDRR LKLAIVLARE LIGTPRHLSQ 490 500 510 520 530 540 HPGGFVLTHD RLDELVPIEP AAMPNRQVIE WDKDDIDALK FMKVDCLALG MLTCMKRAFN 550 560 570 580 590 600 FLAEAKGTEL DLATIPSEDP RTYAMIRKAD TLGTFQIESR AQMAMLPRMK PRTFYDLVIE 610 620 630 640 650 660 VAIVRPGPIQ GDMVHPYLRR REGKEPVVFP KPELEKVLGK TLGVPLFQEQ AMRVAIECAG 670 680 690 700 710 720 FTPGEADQLR RAMATFKFTG GVSKFKDKLI NGMVDRGYDR EFAEKTFSQL EGFGSYGFPE 730 740 750 760 770 780 SHAASFALIA YASSWMKCWH PDVFCAALLN AQPMGFYAPA QIVRDARDHG VEVRPVCINA 790 800 810 820 830 840 SRWDCTLEPI NDDGFAVRLG FRLIRGLSNK NGAEIVAARA DQPFESVDDL WRRADIPVAS 850 860 870 880 890 900 LVQLAKADAM NESLGLARRE ALWALKALRD EPLELFAAAT QREARTIEEV REPAVSLRLM 910 920 930 940 950 960 TSGGEVVEDY RHVGLTLRQH PASFLRADLS SRRIVTCADA MNACDGKWLT TAGLVLVRQK 970 980 990 1000 1010 1020 PGSAKGVMFI TIEDETGVAN LVIWPSLYER QRRIILAARM IAVQGRIQRE GEVVHLVANH 1030 1040 1050 1060 1070 1080 LTDLSADLAG VGDRDDAFPL SLERGDEFHH GSSGIDPRSV PKGPSSRDIY VPDLRTDSIK VKSRDFR

References

[1]

"Complete sequence of chromosome of Nitrobacter hamburgensis X14." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Ivanova N., Ward B., Arp D., Klotz M., Stein L., O'Mullan G., Starkenburg S., Sayavedra L., Poret-Peterson A.T., Gentry M.E., Bruce D., Richardson P. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: X14 / DSM 10229.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000319 Genomic DNA. Translation: ABE64488.1.
RefSeq	YP_578948.1. NC_007964.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q1QH09.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4031727.
GenomeReviews	Gene locus Nham_3765 in contig CP000319_GR.
KEGG	nha:Nham_3765.
NMPDR	fig|323097.3.peg.2372.
PATRIC	22695639. VBINitHam61822_4811.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG734490.
OMA	YRAKGAI.
ProtClustDB	CLSK881842.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q1QH09_NITHX

Accession

Primary (citable) accession number: Q1QH09

Entry history

Integrated into UniProtKB/TrEMBL:	May 16, 2006
Last sequence update:	May 16, 2006
Last modified:	December 14, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)