Reviewed, UniProtKB/Swiss-Prot Q1QFN5 (GLK_NITHX)

Names and origin

Protein names

Recommended name:
    Glucokinase
    EC=2.7.1.2
Alternative name(s):
    Glucose kinase

Gene names

Name:	glk
Ordered Locus Names:	Nham_4371

Encoded on

Plasmid pNITHX2

Organism

Nitrobacter hamburgensis (strain X14 / DSM 10229) [Complete proteome] [HAMAP]

Taxonomic identifier

323097 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Nitrobacter

Protein attributes

Sequence length	320 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + D-glucose = ADP + D-glucose 6-phosphate. HAMAP MF_00524
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the bacterial glucokinase family.

Ontologies

Keywords
Biological process	Glycolysis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome Plasmid
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP glucokinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 320	320	Glucokinase HAMAP MF_00524		PRO_0000268779
Regions
	Nucleotide binding	12 – 17	6	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q1QFN5-1 [UniParc]. Last modified December 12, 2006. Version 2. Checksum: 3963475A2D8C2835	FASTA	320	33,719
	10 20 30 40 50 60 MGKSMTALRV IGDIGGTYAR FAVAERGKYS ELQHLSVSKY AALKDALGEY LAALPRDLRP 70 80 90 100 110 120 TRGALAVAGP VSGDEVKLTN LNWSFSITAL KADLGMSSLV VVNDFAATAM SVPYLPEADC 130 140 150 160 170 180 YPIGPPQSKT SGPVGVIGPG TGLGVSALVP DAGRWILLPG EGGHSTLPPA TQAESLIVEV 190 200 210 220 230 240 LRTHWPHVSA ERALSGAGLV NLYQALCSIE GKRPDPLSPA DVTDRAMRGS DPTCVKAFEV 250 260 270 280 290 300 FCSMLGTVAG DLALTIGATG GIYIAGGILL RFKEAFASSP FRDRFEDKGR FQDYLRRIPT 310 320 LLILEESPAL LGLANLPLEP

References

[1]

"Complete sequence of plasmid 2 of Nitrobacter hamburgensis X14." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Ivanova N., Ward B., Arp D., Klotz M., Stein L., O'Mullan G., Starkenburg S., Sayavedra L., Poret-Peterson A.T., Gentry M.E., Bruce D., Richardson P. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000321 Genomic DNA. Translation: ABE64962.1. Different initiation.
RefSeq	YP_571794.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4025231.
GenomeReviews	Gene locus Nham_4371 in contig CP000321_GR.
KEGG	nha:Nham_4371.
NMPDR	fig|323097.3.peg.3820.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q1QFN5.
Enzyme and pathway databases
BioCyc	NHAM323097:NHAM_4371-MON.
Family and domain databases
HAMAP	MF_00524. [Tree]
InterPro	IPR003836. Glucokinase. [Graphical view]
Pfam	PF02685. Glucokinase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00749. glk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLK_NITHX

Accession

Primary (citable) accession number: Q1QFN5

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 12, 2006
Last sequence update:	December 12, 2006
Last modified:	June 16, 2009
This is version 18 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)