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Q1QFN5 (GLK_NITHX) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucokinase

EC=2.7.1.2
Alternative name(s):
Glucose kinase
Gene names
Name:glk
Ordered Locus Names:Nham_4371
Encoded onPlasmid pNITHX2
OrganismNitrobacter hamburgensis (strain X14 / DSM 10229) [Complete proteome] [HAMAP]
Taxonomic identifier323097 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeNitrobacter

Protein attributes

Sequence length320 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-glucose = ADP + D-glucose 6-phosphate. HAMAP-Rule MF_00524

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00524.

Sequence similarities

Belongs to the bacterial glucokinase family.

Sequence caution

The sequence ABE64962.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Plasmid
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glucokinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 320320Glucokinase HAMAP-Rule MF_00524
PRO_0000268779

Regions

Nucleotide binding12 – 176ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q1QFN5 [UniParc].

Last modified December 12, 2006. Version 2.
Checksum: 3963475A2D8C2835

FASTA32033,719
        10         20         30         40         50         60 
MGKSMTALRV IGDIGGTYAR FAVAERGKYS ELQHLSVSKY AALKDALGEY LAALPRDLRP 

        70         80         90        100        110        120 
TRGALAVAGP VSGDEVKLTN LNWSFSITAL KADLGMSSLV VVNDFAATAM SVPYLPEADC 

       130        140        150        160        170        180 
YPIGPPQSKT SGPVGVIGPG TGLGVSALVP DAGRWILLPG EGGHSTLPPA TQAESLIVEV 

       190        200        210        220        230        240 
LRTHWPHVSA ERALSGAGLV NLYQALCSIE GKRPDPLSPA DVTDRAMRGS DPTCVKAFEV 

       250        260        270        280        290        300 
FCSMLGTVAG DLALTIGATG GIYIAGGILL RFKEAFASSP FRDRFEDKGR FQDYLRRIPT 

       310        320 
LLILEESPAL LGLANLPLEP 

« Hide

References

[1]"Complete sequence of plasmid 2 of Nitrobacter hamburgensis X14."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Ivanova N., Ward B., Arp D., Klotz M., Stein L., O'Mullan G., Starkenburg S., Sayavedra L., Poret-Peterson A.T., Gentry M.E., Bruce D., Richardson P.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: X14 / DSM 10229.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000321 Genomic DNA. Translation: ABE64962.1. Different initiation.
RefSeqYP_571794.1. NC_007960.1.

3D structure databases

ProteinModelPortalQ1QFN5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING323097.Nham_4371.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE64962; ABE64962; Nham_4371.
GeneID4025231.
KEGGnha:Nham_4371.
PATRIC22686667. VBINitHam61822_0379.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0837.
HOGENOMHOG000274469.
KOK00845.
OrthoDBEOG64BQ47.

Enzyme and pathway databases

BioCycNHAM323097:GHP7-4437-MONOMER.

Family and domain databases

HAMAPMF_00524. Glucokinase.
InterProIPR003836. Glucokinase.
[Graphical view]
PfamPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00749. glk. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLK_NITHX
AccessionPrimary (citable) accession number: Q1QFN5
Entry history
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: December 12, 2006
Last modified: June 11, 2014
This is version 46 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families