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Q1Q993 (UPPP_PSYCK) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:Pcryo_1983
OrganismPsychrobacter cryohalolentis (strain K5) [Complete proteome] [HAMAP]
Taxonomic identifier335284 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaePsychrobacter

Protein attributes

Sequence length280 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 280280Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000250250

Regions

Transmembrane3 – 2321Helical; Potential
Transmembrane45 – 6521Helical; Potential
Transmembrane88 – 10821Helical; Potential
Transmembrane115 – 13521Helical; Potential
Transmembrane150 – 17021Helical; Potential
Transmembrane191 – 21121Helical; Potential
Transmembrane225 – 24521Helical; Potential
Transmembrane255 – 27521Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q1Q993 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: 53BE27FCDC218D31

FASTA28030,557
        10         20         30         40         50         60 
MDIILLIQAV IMGIVEGITE FLPISSTGYL ILSADLMGFW TKEKVDLFVV VVQFGAILAV 

        70         80         90        100        110        120 
IYDYWGRLWQ ALMGLLTGKA EGMSNPRQLG LSLIVATIPV MIVGFTFADE IKAYLFNPIV 

       130        140        150        160        170        180 
VAIMLIIGGL LIFYVENRPK AIIAEEAEDV SLKTALMIGL LQCLALIPGT SRSGATIIGA 

       190        200        210        220        230        240 
LWLGVSRKAS AEFSFFLGIP VIIGAALLDF IKHRDVLTSS EDWLVLGIGT VVSFIIALLC 

       250        260        270        280 
IRLLVAWVSR RDFKIFAWLR IITGVLVLIA AWGFGYQMAG 

« Hide

References

[1]"Complete sequence of chromosome of Psychrobacter cryohalolentis K5."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Sims D.R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Richardson P.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K5.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000323 Genomic DNA. Translation: ABE75760.1.
RefSeqYP_581244.1. NC_007969.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING335284.Pcryo_1983.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE75760; ABE75760; Pcryo_1983.
GeneID4035080.
KEGGpcr:Pcryo_1983.
PATRIC23063583. VBIPsyCry128170_2106.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218356.
KOK06153.
OMAIFAWLRI.
OrthoDBEOG6QP13M.
ProtClustDBPRK00281.

Enzyme and pathway databases

BioCycPCRY335284:GHE9-2025-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_PSYCK
AccessionPrimary (citable) accession number: Q1Q993
Entry history
Integrated into UniProtKB/Swiss-Prot: September 19, 2006
Last sequence update: May 16, 2006
Last modified: February 19, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families