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Q1Q963

- TRMB_PSYCK

UniProt

Q1Q963 - TRMB_PSYCK

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Protein

tRNA (guanine-N(7)-)-methyltransferase

Gene

trmB

Organism
Psychrobacter cryohalolentis (strain K5)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei105 – 1051S-adenosyl-L-methionineUniRule annotation
Binding sitei130 – 1301S-adenosyl-L-methionineUniRule annotation
Binding sitei157 – 1571S-adenosyl-L-methionineUniRule annotation
Active sitei179 – 1791By similarity
Binding sitei179 – 1791S-adenosyl-L-methionineUniRule annotation
Binding sitei183 – 1831SubstrateUniRule annotation
Binding sitei215 – 2151SubstrateUniRule annotation

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciPCRY335284:GHE9-2055-MONOMER.
UniPathwayiUPA00989.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation (EC:2.1.1.33UniRule annotation)
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferaseUniRule annotation
tRNA(m7G46)-methyltransferaseUniRule annotation
Gene namesi
Name:trmBUniRule annotation
Ordered Locus Names:Pcryo_2013
OrganismiPsychrobacter cryohalolentis (strain K5)
Taxonomic identifieri335284 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaePsychrobacter
ProteomesiUP000002425: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 273273tRNA (guanine-N(7)-)-methyltransferasePRO_0000288205Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi335284.Pcryo_2013.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni252 – 2554Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0220.
HOGENOMiHOG000073968.
KOiK03439.
OMAiMSTENEN.
OrthoDBiEOG6K6VBC.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01057. tRNA_methyltr_TrmB.
InterProiIPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamiPF02390. Methyltransf_4. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1Q963-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSQHPDINTN VDATSLTDDQ KSLDTNATSG NEVAPDGNKH IRIVNTFMKR
60 70 80 90 100
RTHMNKNAEL ALTAPEFAHY LVNNSFGDGN LEGIDDLRAL FAELPNGSEA
110 120 130 140 150
PLTLEIGFGL GDSFIEMAAA EPSRNFVGIE VHEPGIGKCA YMAGTQNLSN
160 170 180 190 200
VRIINGDAIQ LLKQLPENHI DRIQLYFPDP WQKKRHHKRR FVSPERMAIV
210 220 230 240 250
TRSLKQGGWF HTATDWEHYA FWMVEVLDGF VGLSNQAGAG NFTSRPDFRP
260 270
MTKFERRGLA SGHGVWDLIY LKD
Length:273
Mass (Da):30,592
Last modified:May 16, 2006 - v1
Checksum:iC58090BD003084E6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000323 Genomic DNA. Translation: ABE75790.1.
RefSeqiYP_581274.1. NC_007969.1.

Genome annotation databases

EnsemblBacteriaiABE75790; ABE75790; Pcryo_2013.
GeneIDi4034959.
KEGGipcr:Pcryo_2013.
PATRICi23063643. VBIPsyCry128170_2136.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000323 Genomic DNA. Translation: ABE75790.1 .
RefSeqi YP_581274.1. NC_007969.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 335284.Pcryo_2013.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABE75790 ; ABE75790 ; Pcryo_2013 .
GeneIDi 4034959.
KEGGi pcr:Pcryo_2013.
PATRICi 23063643. VBIPsyCry128170_2136.

Phylogenomic databases

eggNOGi COG0220.
HOGENOMi HOG000073968.
KOi K03439.
OMAi MSTENEN.
OrthoDBi EOG6K6VBC.

Enzyme and pathway databases

UniPathwayi UPA00989 .
BioCyci PCRY335284:GHE9-2055-MONOMER.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_01057. tRNA_methyltr_TrmB.
InterProi IPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view ]
Pfami PF02390. Methyltransf_4. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
TIGRFAMsi TIGR00091. TIGR00091. 1 hit.
PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome of Psychrobacter cryohalolentis K5."
    US DOE Joint Genome Institute
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Sims D.R., Gilna P., Schmutz J.
    , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Richardson P.
    Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K5.

Entry informationi

Entry nameiTRMB_PSYCK
AccessioniPrimary (citable) accession number: Q1Q963
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: May 16, 2006
Last modified: October 1, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3