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Q1Q946 (Q1Q946_PSYCK) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
Ordered Locus Names:Pcryo_2030 EMBL ABE75807.1
OrganismPsychrobacter cryohalolentis (strain K5) [Complete proteome] [HAMAP] EMBL ABE75807.1
Taxonomic identifier335284 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaePsychrobacter

Protein attributes

Sequence length379 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS011095

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS011095

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS011095.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS011095

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain179 – 376198ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding205 – 26056ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding3301Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3431Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3431Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding3451Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
Q1Q946 [UniParc].

Last modified May 16, 2006. Version 1.
Checksum: DA17D68F493E8BA6

FASTA37941,383
        10         20         30         40         50         60 
MNNTKENNNI DEDGVNVEQN ATDNSNNNIK GNVQNNTAPI INPETALAAA AQAEQDKVNN 

        70         80         90        100        110        120 
NSQSANTLPA IKESKVKEGN EFGRVAVIYG GNSNERSVSL DSGAAVLQAL QNQGVDATHF 

       130        140        150        160        170        180 
DPKHQDITEL RQYDRVFNVL HGRGGEDGLL QGVLQWFDIP QTGSGILASA LGMDKVRTKQ 

       190        200        210        220        230        240 
LWQGCGLSTA PFSLLTADTD WQQVVNMLGL PLIIKPVHEG SSIGMTKVNN LDELPAAYAT 

       250        260        270        280        290        300 
AVQCGDVVMA ERWITGREFT IVIIDDEAYP VIRLEPADIT NFYDFEAKYN RNDTSYYIPC 

       310        320        330        340        350        360 
GLSAADEKHL QDLSLSAFRA VDAKGWGRID AMQDEAGNFW LLEINTVPGM TSHSLVPMAA 

       370 
KARGMDFESL CWHILAQTV 

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References

[1]"Complete sequence of chromosome of Psychrobacter cryohalolentis K5."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Sims D.R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Richardson P.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K5.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000323 Genomic DNA. Translation: ABE75807.1.
RefSeqYP_581291.1. NC_007969.1.

3D structure databases

ProteinModelPortalQ1Q946.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING335284.Pcryo_2030.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABE75807; ABE75807; Pcryo_2030.
GeneID4035403.
KEGGpcr:Pcryo_2030.
PATRIC23063679. VBIPsyCry128170_2154.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1181.
HOGENOMHOG000011592.
KOK01921.
OMAANDTQYR.
OrthoDBEOG6ND0KB.

Enzyme and pathway databases

BioCycPCRY335284:GHE9-2072-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ1Q946_PSYCK
AccessionPrimary (citable) accession number: Q1Q946
Entry history
Integrated into UniProtKB/TrEMBL: May 16, 2006
Last sequence update: May 16, 2006
Last modified: June 11, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)