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Protein

Homoserine kinase

Gene

thrB

Organism
Psychrobacter cryohalolentis (strain K5)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-homoserine = ADP + O-phospho-L-homoserine.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. homoserine kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. threonine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationImported, Transferase

Keywords - Biological processi

Amino-acid biosynthesis, Threonine biosynthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciPCRY335284:GHE9-2442-MONOMER.
UniPathwayiUPA00050; UER00064.

Names & Taxonomyi

Protein namesi
Recommended name:
Homoserine kinaseUniRule annotation (EC:2.7.1.39UniRule annotation)
Short name:
HKUniRule annotation
Short name:
HSKUniRule annotation
Gene namesi
Name:thrBUniRule annotation
Ordered Locus Names:Pcryo_2390Imported
OrganismiPsychrobacter cryohalolentis (strain K5)Imported
Taxonomic identifieri335284 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaePsychrobacter
ProteomesiUP000002425 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi335284.Pcryo_2390.

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudomonas-type ThrB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2334.
HOGENOMiHOG000004810.
KOiK02204.
OMAiINDFCTT.
OrthoDBiEOG6BW4W1.

Family and domain databases

HAMAPiMF_00301. Homoser_kinase_2.
InterProiIPR002575. Aminoglycoside_PTrfase.
IPR005280. Homoserine_kinase_ThrB.
IPR011009. Kinase-like_dom.
[Graphical view]
PfamiPF01636. APH. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1Q836-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVYTQLTDD QFATFCQRFG VSFARAIPIT QGIKNSNWFI QTTDDVDGAH
60 70 80 90 100
SYVFTLFEER PPEDIEKMAV ILNQLDGKLP VAAPLSLVDS AEKCYVIRYD
110 120 130 140 150
NKAITLVPCL AGSHPQQTTQ AMCHEIGASL AVLHETLQQL QPAEEYGVPL
160 170 180 190 200
YPWSEVRDRE KQFMPADEAK LMSDIWQSYT DLPLATLPKG LCHLDMFADN
210 220 230 240 250
TLWNLSLNNS QKGEAHLTGL LDFTEVSVEH YVMDIAITIN DFCTTWGMAE
260 270 280 290 300
QGESVNFDRS KMAAFLQGYE SKRMLGEDEK RALPVMLAKA AVIFWLLRLN
310 320 330 340 350
VIHYNRTEGR TGDNIMVKNP DLMKRLAAYH WSHVEKAQNT VFVLLAINNK
360 370 380
IEKPIAGVFS SITQAEQTCD SLGNSSDFII KEYTLDQLV
Length:389
Mass (Da):43,847
Last modified:May 16, 2006 - v1
Checksum:iB2A25185778F776F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000323 Genomic DNA. Translation: ABE76167.1.
RefSeqiYP_581651.1. NC_007969.1.

Genome annotation databases

EnsemblBacteriaiABE76167; ABE76167; Pcryo_2390.
KEGGipcr:Pcryo_2390.
PATRICi23064437. VBIPsyCry128170_2523.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000323 Genomic DNA. Translation: ABE76167.1.
RefSeqiYP_581651.1. NC_007969.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi335284.Pcryo_2390.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABE76167; ABE76167; Pcryo_2390.
KEGGipcr:Pcryo_2390.
PATRICi23064437. VBIPsyCry128170_2523.

Phylogenomic databases

eggNOGiCOG2334.
HOGENOMiHOG000004810.
KOiK02204.
OMAiINDFCTT.
OrthoDBiEOG6BW4W1.

Enzyme and pathway databases

UniPathwayiUPA00050; UER00064.
BioCyciPCRY335284:GHE9-2442-MONOMER.

Family and domain databases

HAMAPiMF_00301. Homoser_kinase_2.
InterProiIPR002575. Aminoglycoside_PTrfase.
IPR005280. Homoserine_kinase_ThrB.
IPR011009. Kinase-like_dom.
[Graphical view]
PfamiPF01636. APH. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome of Psychrobacter cryohalolentis K5."
    US DOE Joint Genome Institute
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Sims D.R., Gilna P., Schmutz J.
    , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Richardson P.
    Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K5Imported.

Entry informationi

Entry nameiQ1Q836_PSYCK
AccessioniPrimary (citable) accession number: Q1Q836
Entry historyi
Integrated into UniProtKB/TrEMBL: May 16, 2006
Last sequence update: May 16, 2006
Last modified: April 1, 2015
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.