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Protein

Diacylglycerol kinase 4

Gene

DGK4

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Phosphorylates the second messenger diacylglycerol (DAG) to generate phosphatidic acid (PA), another important signaling molecule. PA is required for plant development and responses to abiotic stress and pathogen attack. May be involved in the accumulation of PA during cold stress (By similarity).By similarity

Catalytic activityi

ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processPlant defense, Stress response
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT5G57690-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Diacylglycerol kinase 4 (EC:2.7.1.107)
Short name:
AtDGK4
Short name:
DAG kinase 4
Alternative name(s):
Diglyceride kinase 4
Short name:
DGK 4
Gene namesi
Name:DGK4
Ordered Locus Names:At5g57690
ORF Names:MRI1.5
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi

Organism-specific databases

AraportiAT5G57690
TAIRilocus:2172575 AT5G57690

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004221121 – 487Diacylglycerol kinase 4Add BLAST487

Proteomic databases

PaxDbiQ1PDI2
PRIDEiQ1PDI2

Expressioni

Gene expression databases

ExpressionAtlasiQ1PDI2 baseline and differential
GenevisibleiQ1PDI2 AT

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi3702.AT5G57690.1

Structurei

3D structure databases

ProteinModelPortaliQ1PDI2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini86 – 242DAGKcPROSITE-ProRule annotationAdd BLAST157

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1169 Eukaryota
ENOG410XQVB LUCA
HOGENOMiHOG000239559
InParanoidiQ1PDI2
KOiK00901
OMAiYLANGPI
OrthoDBiEOG09360AZ1
PhylomeDBiQ1PDI2

Family and domain databases

Gene3Di3.40.50.10330, 1 hit
InterProiView protein in InterPro
IPR017438 ATP-NAD_kinase_N
IPR037607 DGK
IPR000756 Diacylglycerol_kin_accessory
IPR001206 Diacylglycerol_kinase_cat_dom
IPR016961 Diacylglycerol_kinase_pln
IPR016064 NAD/diacylglycerol_kinase_sf
PANTHERiPTHR11255 PTHR11255, 1 hit
PfamiView protein in Pfam
PF00609 DAGK_acc, 1 hit
PF00781 DAGK_cat, 1 hit
PIRSFiPIRSF030829 Diacylglycerol_kinase_pln, 1 hit
SMARTiView protein in SMART
SM00045 DAGKa, 1 hit
SM00046 DAGKc, 1 hit
SUPFAMiSSF111331 SSF111331, 2 hits
PROSITEiView protein in PROSITE
PS50146 DAGK, 1 hit

Sequencei

Sequence statusi: Complete.

Q1PDI2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESPSIGDSL TARMIPRHSS LDSFGAMKVS LLVNLASIRV SKAELRQRVM
60 70 80 90 100
LPQYLRIAIR DCILRKDDSF DASSSVAPPL ENNALTPEVP LMVFVNPKSG
110 120 130 140 150
GRQGPLIKER LQNLISEEQV YDLTEVKPNE FIRYGLGCLE AFASRGDECA
160 170 180 190 200
KEIREKMRIV VAGGDGTVGW VLGCLGELNL QNRLPVPPVS IMPLGTGNDL
210 220 230 240 250
SRSFGWGGSF PFAWKSAIKR TLHRASVAPI SRLDSWNILI TMPSGEIVDP
260 270 280 290 300
PYSLKATQEC YIDQNLEIEG EIPPSTNGYE GVFYNYFSIG MDAQVAYGFH
310 320 330 340 350
HLRNEKPYLA NGPIANKIIY SGYGCSQGWF LTHCINDPGL RGLKNIMTLH
360 370 380 390 400
IKKLDSSEWE KVPVPKSVRA VVALNLHSYG SGRNPWGNLK QDYLEKRGFV
410 420 430 440 450
EAQADDGLLE IFGLKQGWHA SFVMVELISA KHIAQAAAIR LEIRGGDWKD
460 470 480
AFMQMDGEPW KQPMTRDYST FVDIKRVPHQ SLVVKGD
Length:487
Mass (Da):54,181
Last modified:May 16, 2006 - v1
Checksum:i854450C00B8CE355
GO

Sequence cautioni

The sequence BAB09587 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB018118 Genomic DNA Translation: BAB09587.1 Sequence problems.
CP002688 Genomic DNA Translation: AED96936.1
DQ447086 mRNA Translation: ABE66256.1
RefSeqiNP_200577.2, NM_125152.3
UniGeneiAt.55605

Genome annotation databases

EnsemblPlantsiAT5G57690.1; AT5G57690.1; AT5G57690
GeneIDi835876
GrameneiAT5G57690.1; AT5G57690.1; AT5G57690
KEGGiath:AT5G57690

Entry informationi

Entry nameiDGK4_ARATH
AccessioniPrimary (citable) accession number: Q1PDI2
Secondary accession number(s): Q9FHH4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2013
Last sequence update: May 16, 2006
Last modified: May 23, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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