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Protein

Putative mitochondrial ATP-dependent helicase irc3

Gene

irc3

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi53 – 60ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Helicase, Hydrolase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative mitochondrial ATP-dependent helicase irc3 (EC:3.6.4.-)
Gene namesi
Name:irc3
ORF Names:SPBC11C11.11c, SPBC3B8.12
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC11C11.11c.
PomBaseiSPBC11C11.11c. irc3.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: PomBase
  • cytoplasmic ribonucleoprotein granule Source: GO_Central
  • mitochondrion Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003538171 – 606Putative mitochondrial ATP-dependent helicase irc3Add BLAST606

Proteomic databases

MaxQBiQ1MTR1.
PRIDEiQ1MTR1.

Interactioni

Protein-protein interaction databases

BioGridi276171. 9 interactors.

Structurei

3D structure databases

ProteinModelPortaliQ1MTR1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini40 – 201Helicase ATP-bindingPROSITE-ProRule annotationAdd BLAST162
Domaini246 – 398Helicase C-terminalPROSITE-ProRule annotationAdd BLAST153

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi148 – 151DEAH box4

Sequence similaritiesi

Belongs to the helicase family. IRC3 subfamily.Curated
Contains 1 helicase ATP-binding domain.PROSITE-ProRule annotation
Contains 1 helicase C-terminal domain.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000180925.
InParanoidiQ1MTR1.
KOiK17677.
OMAiTHKISEY.
OrthoDBiEOG092C1DDQ.
PhylomeDBiQ1MTR1.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR006935. Helicase/UvrB_N.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00271. Helicase_C. 1 hit.
PF04851. ResIII. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1MTR1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLNACCKKN LWPRNGSTIF RRFALKLRPY QEECLSACLN AFDEGKRRIA
60 70 80 90 100
VSLATGSGKT ALFPHFIKYA PTLRPNSEQC LILVHRKELA LQALKHCRES
110 120 130 140 150
LPNKSIEIDM GNQCASGLAD VTVASVFSLK NERLLKYNPL NFKLLIFDEV
160 170 180 190 200
HHMASPSYLR ILEHFGAESE KSKVNVIGLT ATLFRADGKG LACGLDEIVY
210 220 230 240 250
HRHFVDMIKD NWLVEPKVIN IKWSTDLVLA DSSSFLDQEK LKKEAQSEKA
260 270 280 290 300
IFEIPRAWLE HASNRSSTLV FCINVEHSLK VCNAFRKLGI DARALFGETN
310 320 330 340 350
DSERETLIQD FRKKKFPVLV NCMVLTEGTD IPNIDCLMIA RPTSSPNLLT
360 370 380 390 400
QMIGRGLRLH EGKRDCLILD FCDSLRRVSL HVDPTLAGLS PDEVENFYNK
410 420 430 440 450
SKNSLANPDY DPKIYGLQSV LWYSKLRKLI EMMDNIKNKD RSIFNLSTNA
460 470 480 490 500
WVAVGMGRYV LSFLQKVLII DTNFEDGTHK ISEYTKEKLG TRVYNRKRIV
510 520 530 540 550
SDRIPSLKFA IRAAETYISN LKTPRSLISR KAVWRMRPAS VRQINFLKKS
560 570 580 590 600
NLKLDEKLLT AGVAADMITK VIYGGKGRQV RTDKLQSYLK HDANLKRITT

LKELKG
Length:606
Mass (Da):68,943
Last modified:August 21, 2007 - v2
Checksum:i97F729852B824547
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA20693.2.
RefSeqiXP_001713145.1. XM_001713093.1.

Genome annotation databases

EnsemblFungiiSPBC11C11.11c.1; SPBC11C11.11c.1:pep; SPBC11C11.11c.
GeneIDi2539613.
KEGGispo:SPBC11C11.11c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA20693.2.
RefSeqiXP_001713145.1. XM_001713093.1.

3D structure databases

ProteinModelPortaliQ1MTR1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi276171. 9 interactors.

Proteomic databases

MaxQBiQ1MTR1.
PRIDEiQ1MTR1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC11C11.11c.1; SPBC11C11.11c.1:pep; SPBC11C11.11c.
GeneIDi2539613.
KEGGispo:SPBC11C11.11c.

Organism-specific databases

EuPathDBiFungiDB:SPBC11C11.11c.
PomBaseiSPBC11C11.11c. irc3.

Phylogenomic databases

HOGENOMiHOG000180925.
InParanoidiQ1MTR1.
KOiK17677.
OMAiTHKISEY.
OrthoDBiEOG092C1DDQ.
PhylomeDBiQ1MTR1.

Miscellaneous databases

PROiQ1MTR1.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR006935. Helicase/UvrB_N.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00271. Helicase_C. 1 hit.
PF04851. ResIII. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiIRC3_SCHPO
AccessioniPrimary (citable) accession number: Q1MTR1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 4, 2008
Last sequence update: August 21, 2007
Last modified: October 5, 2016
This is version 72 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.