Q1MTQ9 (NIP7_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
60S ribosome subunit biogenesis protein nip7

Gene names

Name:	nip7
ORF Names:	SPCC320.11c, SPCC330.18

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]

Taxonomic identifier

284812 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › Schizosaccharomyces pombe

Protein attributes

Sequence length	180 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly By similarity.
Subunit structure	Interacts with pre-ribosome complex By similarity.
Subcellular location	Cytoplasm. Nucleus › nucleolus Ref.2.
Sequence similarities	Belongs to the NIP7 family. Contains 1 PUA domain.

Ontologies

Keywords
Biological process	Ribosome biogenesis
Cellular component	Cytoplasm Nucleus
Ligand	RNA-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	ribosome assembly Inferred from electronic annotation. Source: InterPro ribosome biogenesis Inferred from sequence or structural similarity. Source: PomBase
Cellular_component	cytosol Inferred from direct assay Ref.2. Source: PomBase nucleolus Inferred from direct assay Ref.2. Source: PomBase
Molecular_function	RNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 180	180	60S ribosome subunit biogenesis protein nip7		PRO_0000343163
Regions
	Domain	94 – 170	77	PUA

Sequences

	Sequence		Length	Mass (Da)
	Q1MTQ9 [UniParc]. Last modified August 21, 2007. Version 1. Checksum: 3BD74E9686E9D244	FASTA	180	20,860
	10 20 30 40 50 60 MRPLTHEETK TFFEKLAQYI GKNITHLIDR PDDPHCFRLQ KDRVYYVSER AMKMATSVAR 70 80 90 100 110 120 QNLMSLGICF GKFTKTNKFR LHITALDYIA QYARYKIWVK SNGEMPFLYG NHVLKAHVGR 130 140 150 160 170 180 ITDDTPQHQG VVIYSMNDTP LGFGVTARST LELRRLEPTA IVAFHQADVG EYLRDEDTLF

References

[1]

"The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P. Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 972 / ATCC 24843.

[2]

"ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe." Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M. Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU329672 Genomic DNA. Translation: CAA20923.1.
PIR	T41300.
RefSeq	NP_587718.1. NM_001022713.2.
3D structure databases
ProteinModelPortal	Q1MTQ9.
SMR	Q1MTQ9. Positions 1-176.
ModBase	Search...
Protein-protein interaction databases
STRING	4896.SPCC320.11c-1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	SPCC320.11c.1; SPCC320.11c.1:pep; SPCC320.11c.
GeneID	2539255.
KEGG	spo:SPCC320.11c.
Organism-specific databases
PomBase	SPCC320.11c.
Phylogenomic databases
eggNOG	COG1374.
HOGENOM	HOG000168475.
KO	K07565.
OMA	NGEMPFL.
OrthoDB	EOG4SBJ77.
Family and domain databases
InterPro	IPR002478. PUA. IPR015947. PUA-like_domain. IPR005155. Rbsml_synth_fac_NIP7-like. IPR016686. Ribosomal_synth_fac_NIP7. [Graphical view]
PANTHER	PTHR23415:SF4. PTHR23415:SF4. 1 hit.
Pfam	PF03657. UPF0113. 1 hit. [Graphical view]
PIRSF	PIRSF017190. Rbsml_synth_fac_NIP7. 1 hit.
SMART	SM00359. PUA. 1 hit. [Graphical view]
SUPFAM	SSF88697. PUA-like. 1 hit.
PROSITE	PS50890. PUA. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	20800425.

Entry information

Entry name

NIP7_SCHPO

Accession

Primary (citable) accession number: Q1MTQ9

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 2008
Last sequence update:	August 21, 2007
Last modified:	May 1, 2013
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program