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Protein

60S ribosome subunit biogenesis protein nip7

Gene

nip7

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Ribosome biogenesis

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosome subunit biogenesis protein nip7
Gene namesi
Name:nip7
ORF Names:SPCC320.11c, SPCC330.18
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:SPCC320.11c.
PomBaseiSPCC320.11c. nip7.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: PomBase
  • nucleolus Source: PomBase
  • nucleus Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 18018060S ribosome subunit biogenesis protein nip7PRO_0000343163Add
BLAST

Proteomic databases

MaxQBiQ1MTQ9.

Interactioni

Subunit structurei

Interacts with pre-ribosome complex.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ1MTQ9.
SMRiQ1MTQ9. Positions 1-176.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini94 – 17077PUAPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the NIP7 family.Curated
Contains 1 PUA domain.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000168475.
InParanoidiQ1MTQ9.
KOiK07565.
OMAiVVKAHVG.
OrthoDBiEOG7K0ZQF.
PhylomeDBiQ1MTQ9.

Family and domain databases

Gene3Di2.30.130.10. 1 hit.
InterProiIPR002478. PUA.
IPR015947. PUA-like_domain.
IPR005155. Rbsml_synth_fac_NIP7-like.
IPR016686. Ribosomal_synth_fac_NIP7.
[Graphical view]
PfamiPF03657. UPF0113. 1 hit.
[Graphical view]
PIRSFiPIRSF017190. Rbsml_synth_fac_NIP7. 1 hit.
SMARTiSM00359. PUA. 1 hit.
[Graphical view]
SUPFAMiSSF88697. SSF88697. 1 hit.
PROSITEiPS50890. PUA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1MTQ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPLTHEETK TFFEKLAQYI GKNITHLIDR PDDPHCFRLQ KDRVYYVSER
60 70 80 90 100
AMKMATSVAR QNLMSLGICF GKFTKTNKFR LHITALDYIA QYARYKIWVK
110 120 130 140 150
SNGEMPFLYG NHVLKAHVGR ITDDTPQHQG VVIYSMNDTP LGFGVTARST
160 170 180
LELRRLEPTA IVAFHQADVG EYLRDEDTLF
Length:180
Mass (Da):20,860
Last modified:August 21, 2007 - v1
Checksum:i3BD74E9686E9D244
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAA20923.1.
PIRiT41300.
RefSeqiNP_587718.1. NM_001022713.2.

Genome annotation databases

EnsemblFungiiSPCC320.11c.1; SPCC320.11c.1:pep; SPCC320.11c.
GeneIDi2539255.
KEGGispo:SPCC320.11c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAA20923.1.
PIRiT41300.
RefSeqiNP_587718.1. NM_001022713.2.

3D structure databases

ProteinModelPortaliQ1MTQ9.
SMRiQ1MTQ9. Positions 1-176.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiQ1MTQ9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPCC320.11c.1; SPCC320.11c.1:pep; SPCC320.11c.
GeneIDi2539255.
KEGGispo:SPCC320.11c.

Organism-specific databases

EuPathDBiFungiDB:SPCC320.11c.
PomBaseiSPCC320.11c. nip7.

Phylogenomic databases

HOGENOMiHOG000168475.
InParanoidiQ1MTQ9.
KOiK07565.
OMAiVVKAHVG.
OrthoDBiEOG7K0ZQF.
PhylomeDBiQ1MTQ9.

Miscellaneous databases

NextBioi20800425.
PROiQ1MTQ9.

Family and domain databases

Gene3Di2.30.130.10. 1 hit.
InterProiIPR002478. PUA.
IPR015947. PUA-like_domain.
IPR005155. Rbsml_synth_fac_NIP7-like.
IPR016686. Ribosomal_synth_fac_NIP7.
[Graphical view]
PfamiPF03657. UPF0113. 1 hit.
[Graphical view]
PIRSFiPIRSF017190. Rbsml_synth_fac_NIP7. 1 hit.
SMARTiSM00359. PUA. 1 hit.
[Graphical view]
SUPFAMiSSF88697. SSF88697. 1 hit.
PROSITEiPS50890. PUA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
    Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
    Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiNIP7_SCHPO
AccessioniPrimary (citable) accession number: Q1MTQ9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: August 21, 2007
Last modified: November 11, 2015
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.