Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Kinesin-like motor protein 9

Gene

klp9

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Kinesin-like motor protein ionvolved in anaphase B spindle elongation.1 Publication

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi94 – 1018ATPPROSITE-ProRule annotation

GO - Molecular functioni

  • ATPase activity Source: PomBase
  • ATP binding Source: UniProtKB-KW
  • microtubule motor activity Source: PomBase

GO - Biological processi

  • correction of merotelic kinetochore attachment, mitotic Source: PomBase
  • microtubule sliding Source: PomBase
  • mitotic spindle elongation Source: PomBase
Complete GO annotation...

Keywords - Molecular functioni

Motor protein

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-SPO-68884. Mitotic Telophase/Cytokinesis.

Names & Taxonomyi

Protein namesi
Recommended name:
Kinesin-like motor protein 9
Gene namesi
Name:klp9
ORF Names:SPBC15D4.01c, SPBC2D10.21c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC15D4.01c.
PomBaseiSPBC15D4.01c. klp9.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: UniProtKB-KW
  • microtubule Source: UniProtKB-KW
  • microtubule associated complex Source: PomBase
  • nucleoplasm Source: PomBase
  • nucleus Source: PomBase
  • spindle midzone Source: PomBase
  • spindle pole body Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Microtubule, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 633633Kinesin-like motor protein 9PRO_0000353837Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei605 – 6051Phosphoserine1 Publication
Modified residuei611 – 6111Phosphoserine1 Publication
Modified residuei613 – 6131Phosphoserine1 Publication

Post-translational modificationi

Phosphorylated by cdc2 and dephosphorylated by clp1. Dephosphorylation is required for the interaction with ase1.2 Publications

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ1MTQ7.

PTM databases

iPTMnetiQ1MTQ7.

Interactioni

Subunit structurei

Interacts with ase1.1 Publication

Protein-protein interaction databases

BioGridi276328. 5 interactions.

Structurei

3D structure databases

ProteinModelPortaliQ1MTQ7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 392392Kinesin motorPROSITE-ProRule annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili417 – 541125Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.PROSITE-ProRule annotation
Contains 1 kinesin motor domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

InParanoidiQ1MTQ7.
OMAiYSANARE.
OrthoDBiEOG7K6Q3D.
PhylomeDBiQ1MTQ7.

Family and domain databases

Gene3Di3.40.850.10. 2 hits.
InterProiIPR027640. Kinesin-like_fam.
IPR001752. Kinesin_motor_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR24115. PTHR24115. 3 hits.
PfamiPF00225. Kinesin. 1 hit.
[Graphical view]
PRINTSiPR00380. KINESINHEAVY.
SMARTiSM00129. KISc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS50067. KINESIN_MOTOR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1MTQ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIQIFLRVKK AQPSSDASNK YGFLTVLNDY EILLESPEDS HAYRVSKSKT
60 70 80 90 100
LEKASFTKVF PPSCTQLDVF STICAPLIAD SLVNMNDTLL FTLGVSGAGK
110 120 130 140 150
TYTLFGPSDR PGVAFLALDA LFYAIKGREA SPQTVEFLRS QLEKCKIVEA
160 170 180 190 200
SKFLRGEAPL DIKVPNTEYY ASHFPKIEEK NYQYAIYLSF AEIYNDRIFD
210 220 230 240 250
LLEKASFFGH RHALSLKKSS TSDKKSIAGI QKVFVSNTTE AYKLIQKVLQ
260 270 280 290 300
LRKSTSTKSN SVSSRSHLIM SIELFKVCTK SNKFESCQID LVDLAGSERT
310 320 330 340 350
RSAETSGLLL REGASINRSL LTLGQCLEAL RRKHEGKQHI IPFRQSKLTE
360 370 380 390 400
LLFHSGHLSG LAGINMLVNI DPFGSFDENA QVMRYSANAR EILPPPLNEN
410 420 430 440 450
SGSQSPSHSL LQKSKNTSST KALTSHLEQL QQENQQLRML LADADSEMMN
460 470 480 490 500
LEYEIRQQMT REMEERVSEV ERTFLTKLLE ESAQGIEYTD QKLEKMGGWM
510 520 530 540 550
KKLQDENSEK TETIAQLEQI IEELHEELRS LEEESIKESS ATQQNENQHK
560 570 580 590 600
RSSRKLLYED KQAIQEAHTI NTKRKLWPQS TLIQAPNSDD EENVPSPSPK
610 620 630
KKVVSPIKPL SPSRRPPLTS LYSGTTDIDI NEL
Length:633
Mass (Da):71,452
Last modified:August 21, 2007 - v2
Checksum:i16EE7C0E5F557695
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA21179.2.
RefSeqiXP_001713140.1. XM_001713088.2.

Genome annotation databases

EnsemblFungiiSPBC15D4.01c.1; SPBC15D4.01c.1:pep; SPBC15D4.01c.
GeneIDi2539778.
KEGGispo:SPBC15D4.01c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA21179.2.
RefSeqiXP_001713140.1. XM_001713088.2.

3D structure databases

ProteinModelPortaliQ1MTQ7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi276328. 5 interactions.

PTM databases

iPTMnetiQ1MTQ7.

Proteomic databases

MaxQBiQ1MTQ7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC15D4.01c.1; SPBC15D4.01c.1:pep; SPBC15D4.01c.
GeneIDi2539778.
KEGGispo:SPBC15D4.01c.

Organism-specific databases

EuPathDBiFungiDB:SPBC15D4.01c.
PomBaseiSPBC15D4.01c. klp9.

Phylogenomic databases

InParanoidiQ1MTQ7.
OMAiYSANARE.
OrthoDBiEOG7K6Q3D.
PhylomeDBiQ1MTQ7.

Enzyme and pathway databases

ReactomeiR-SPO-68884. Mitotic Telophase/Cytokinesis.

Miscellaneous databases

NextBioi20800927.
PROiQ1MTQ7.

Family and domain databases

Gene3Di3.40.850.10. 2 hits.
InterProiIPR027640. Kinesin-like_fam.
IPR001752. Kinesin_motor_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR24115. PTHR24115. 3 hits.
PfamiPF00225. Kinesin. 1 hit.
[Graphical view]
PRINTSiPR00380. KINESINHEAVY.
SMARTiSM00129. KISc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS50067. KINESIN_MOTOR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
    Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
    Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  3. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-605; SER-611 AND SER-613, IDENTIFICATION BY MASS SPECTROMETRY.
  4. "Phospho-regulated interaction between kinesin-6 Klp9p and microtubule bundler Ase1p promotes spindle elongation."
    Fu C., Ward J.J., Loiodice I., Velve-Casquillas G., Nedelec F.J., Tran P.T.
    Dev. Cell 17:257-267(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION, PHOSPHORYLATION, INTERACTION WITH ASE1.

Entry informationi

Entry nameiKLP9_SCHPO
AccessioniPrimary (citable) accession number: Q1MTQ7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 4, 2008
Last sequence update: August 21, 2007
Last modified: May 11, 2016
This is version 76 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.