Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q1MRQ9

- Q1MRQ9_LAWIP

UniProt

Q1MRQ9 - Q1MRQ9_LAWIP

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glutamate decarboxylase

Gene

gad

Organism
Lawsonia intracellularis (strain PHE/MN1-00)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.

Cofactori

Note: Pyridoxal phosphate.UniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciLINT363253:GH6E-270-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Name:gadImported
Ordered Locus Names:LI0261Imported
OrganismiLawsonia intracellularis (strain PHE/MN1-00)Imported
Taxonomic identifieri363253 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeLawsonia
ProteomesiUP000002430: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi363253.LI0261.

Structurei

3D structure databases

ProteinModelPortaliQ1MRQ9.
SMRiQ1MRQ9. Positions 37-476.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiPTFQINF.
OrthoDBiEOG6TFCPW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1MRQ9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MATARKAVVK KMPVGHGTKR GSMGNRTQKS SMSNGVVRHE LLDDVFAEDD
60 70 80 90 100
LSQTLPKYQM PLYEHRPRDI YQAVHDELML DGNARQNLAT FCQTWVDPEI
110 120 130 140 150
HKLMDECVAK NMIDKDEYPQ TAELEMRCVN MLADLWNSPD PTNTIGCSAI
160 170 180 190 200
GSSEAAMLGG MALKWRWRAQ RKKAGKSTDK PNLVCGPVQI CWHKFARYWD
210 220 230 240 250
IELREIPMEK NRLIMSPEEA IKRCDENTIG VVPTLGVTYT GQYEPVEEVS
260 270 280 290 300
NALDALQKKK GWDIPIHVDA ASGGFLAPFI EPELVWDFRL PRVKSINSSG
310 320 330 340 350
HKFGLAPLGM GWVVWREKTD LPEDLIFWVN YLGSNIPTFA INFSRPGGQI
360 370 380 390 400
VCQYYNLLRL GREGYRRIHQ ACYDTTDYLA NELTKTGIFK ILYGGKTGIP
410 420 430 440 450
ALTWTLKDEK KYPFSLYDLS DRLRTRGWQV PAYSMPANRT DLVVMRVLVR
460 470 480 490 500
HGFDHDLADL LVNDIHRAIE HLKQNPRRKP LGSGQVTSYD HSGRSSIPQK

KK
Length:502
Mass (Da):57,125
Last modified:May 30, 2006 - v1
Checksum:i360AB851B33722E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180252 Genomic DNA. Translation: CAJ54317.1.
RefSeqiYP_594638.1. NC_008011.1.

Genome annotation databases

GeneIDi4060314.
KEGGilip:LI0261.
PATRICi22303891. VBILawInt40445_0291.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180252 Genomic DNA. Translation: CAJ54317.1 .
RefSeqi YP_594638.1. NC_008011.1.

3D structure databases

ProteinModelPortali Q1MRQ9.
SMRi Q1MRQ9. Positions 37-476.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 363253.LI0261.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 4060314.
KEGGi lip:LI0261.
PATRICi 22303891. VBILawInt40445_0291.

Phylogenomic databases

eggNOGi COG0076.
HOGENOMi HOG000070228.
KOi K01580.
OMAi PTFQINF.
OrthoDBi EOG6TFCPW.

Enzyme and pathway databases

BioCyci LINT363253:GH6E-270-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
InterProi IPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view ]
PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
Pfami PF00282. Pyridoxal_deC. 1 hit.
[Graphical view ]
SUPFAMi SSF53383. SSF53383. 1 hit.
TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The complete genome sequence of Lawsonia intracellularis: the causative agent of proliferative enteropathy."
    Kaur K., Zhang Q., Beckler D., Munir S., Li L., Kinsley K., Herron L., Peterson A., May B., Singh S., Gebhart C., Kapur V.
    Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PHE/MN1-00Imported.

Entry informationi

Entry nameiQ1MRQ9_LAWIP
AccessioniPrimary (citable) accession number: Q1MRQ9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 30, 2006
Last sequence update: May 30, 2006
Last modified: November 26, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3