Q1MQQ4 (LFTR_LAWIP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferase
EC=2.3.2.6

Alternative name(s):
L/F-transferase
Leucyltransferase
Phenyalanyltransferase

Gene names

Name:	aat
Ordered Locus Names:	LI0619

Organism

Lawsonia intracellularis (strain PHE/MN1-00) [Complete proteome] [HAMAP]

Taxonomic identifier

363253 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Deltaproteobacteria › Desulfovibrionales › Desulfovibrionaceae › Lawsonia › Lawsonia intracellularis

Protein attributes

Sequence length	228 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine By similarity. HAMAP-Rule MF_00688
Catalytic activity	L-leucyl-tRNA + protein = tRNA + L-leucyl-protein. HAMAP-Rule MF_00688 L-phenylalanyl-tRNA + protein = tRNA + L-phenylalanyl-protein. HAMAP-Rule MF_00688
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00688.
Sequence similarities	Belongs to the L/F-transferase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	protein catabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	leucyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 228	228	Leucyl/phenylalanyl-tRNA--protein transferase HAMAP-Rule MF_00688		PRO_0000258063

Sequences

	Sequence		Length	Mass (Da)
	Q1MQQ4 [UniParc]. Last modified May 30, 2006. Version 1. Checksum: 5E34759D1FDED9D3	FASTA	228	25,748
	10 20 30 40 50 60 MLSALSNDPM YFPPLETAFD NGLLAYGGDL SPQRLLSAYT KGIFPWYDNN SPILWWSPDP 70 80 90 100 110 120 RCILLPENFR IPKTIQRELK KCTFSVTINN AFTEVITACA TLPRTKQKGT WITQDMKMAY 130 140 150 160 170 180 IQLHKLGFSH SIEVWDNSTL VGGLYGVALG KAFFGESMFH IAPHASKLAL VWLAQYLWSY 190 200 210 220 NFDFIDCQMP TTHIMRYGAT LISRNEFLTR LTIAVTTGTS QASTKEAL

References

[1]

"The complete genome sequence of Lawsonia intracellularis: the causative agent of proliferative enteropathy." Kaur K., Zhang Q., Beckler D., Munir S., Li L., Kinsley K., Herron L., Peterson A., May B., Singh S., Gebhart C., Kapur V. Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PHE/MN1-00.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM180252 Genomic DNA. Translation: CAJ54673.1.
RefSeq	YP_594994.1. NC_008011.1.
3D structure databases
ProteinModelPortal	Q1MQQ4.
ModBase	Search...
Protein-protein interaction databases
STRING	363253.LI0619.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4060337.
KEGG	lip:LI0619.
PATRIC	22304685. VBILawInt40445_0674.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2360.
HOGENOM	HOG000102325.
KO	K00684.
OMA	MFYGESM.
ProtClustDB	PRK00301.
Enzyme and pathway databases
BioCyc	LINT363253:GH6E-641-MONOMER.
Family and domain databases
HAMAP	MF_00688. Leu_Phe_trans.
InterPro	IPR016181. Acyl_CoA_acyltransferase. IPR004616. Leu/Phe-tRNA_Trfase. [Graphical view]
Pfam	PF03588. Leu_Phe_trans. 1 hit. [Graphical view]
SUPFAM	SSF55729. Acyl_CoA_acyltransferase. 1 hit.
TIGRFAMs	TIGR00667. aat. 1 hit.
ProtoNet	Search...

Entry information

Entry name

LFTR_LAWIP

Accession

Primary (citable) accession number: Q1MQQ4

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 31, 2006
Last sequence update:	May 30, 2006
Last modified:	May 29, 2013
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program