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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Lawsonia intracellularis (strain PHE/MN1-00)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei139GTPUniRule annotation1
Binding sitei143GTPUniRule annotation1
Binding sitei187GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi21 – 25GTPUniRule annotation5
Nucleotide bindingi108 – 110GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciLINT363253:G1GJC-1228-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotationImported
Ordered Locus Names:LI1109Imported
OrganismiLawsonia intracellularis (strain PHE/MN1-00)Imported
Taxonomic identifieri363253 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeLawsonia
Proteomesi
  • UP000002430 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi363253.LI1109

Structurei

3D structure databases

ProteinModelPortaliQ1MPB4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 205TubulinInterPro annotationAdd BLAST193
Domaini207 – 327Tubulin_CInterPro annotationAdd BLAST121

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK Bacteria
COG0206 LUCA
HOGENOMiHOG000049094
KOiK03531
OMAiMRAVKGI

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q1MPB4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEMLFDTMVP QAKIKVIGVG GGGGNAVQNM IESSLRGVTF ICANTDAQAL
60 70 80 90 100
ARSKADIKLQ IGEKLTKGLG AGAEPAVGRD AALESIGVIK EAIGESDMVF
110 120 130 140 150
VTAGMGGGTG TGAAPIVAQA AKEMGALTVG VVTKPFVFEG HKRSRSADYG
160 170 180 190 200
ISQLREYVDS LITIPNDRLL TIAPKNAKLT DMLKCADDVL YSAVRGISDL
210 220 230 240 250
ITVPGIINVD FADVRTIMSV SGLAMMGTGF ASGEGRAIEA ARRAITSPLL
260 270 280 290 300
EDVSITGAKA ILINITATTE LGIDEYSDAA NYIHEAAQGS GDTNIIIGTA
310 320 330 340 350
FDEEAGDEIR ITVIATGIES QVGVKMQGST SSKAAMPSFR KSSHITNTTS
360 370 380 390 400
FKPEAIKHNL ASEKPRYRTP RLLTNPIEMD YKTQGDHSEI FTEDTGVNYS
410 420 430 440 450
IPTYLRALLG KQGAQSSKEE YDRTHHGDNN KKDTHNPGHE NFVFDGNEQD
460
IPIFIQKQAN
Length:460
Mass (Da):48,886
Last modified:May 30, 2006 - v1
Checksum:iC05C620B48CED3AE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180252 Genomic DNA Translation: CAJ55163.1
RefSeqiWP_011527192.1, NC_008011.1

Genome annotation databases

KEGGilip:LI1109

Similar proteinsi

Entry informationi

Entry nameiQ1MPB4_LAWIP
AccessioniPrimary (citable) accession number: Q1MPB4
Entry historyiIntegrated into UniProtKB/TrEMBL: May 30, 2006
Last sequence update: May 30, 2006
Last modified: March 28, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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