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Q1MMI4 (UPPP_RHIL3) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:RL0328
OrganismRhizobium leguminosarum bv. viciae (strain 3841) [Complete proteome] [HAMAP]
Taxonomic identifier216596 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium

Protein attributes

Sequence length265 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 265265Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000250253

Regions

Transmembrane38 – 5821Helical; Potential
Transmembrane80 – 10021Helical; Potential
Transmembrane107 – 12721Helical; Potential
Transmembrane135 – 15521Helical; Potential
Transmembrane178 – 19821Helical; Potential
Transmembrane216 – 23621Helical; Potential
Transmembrane244 – 26421Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q1MMI4 [UniParc].

Last modified May 30, 2006. Version 1.
Checksum: BC3AB00AACF8D6FB

FASTA26528,649
        10         20         30         40         50         60 
MDYINAAILG VIEGITEFLP ISSTGHLIIA EQWLGHRSDM FNIVIQAGAI LAVTIIYWRR 

        70         80         90        100        110        120 
LVDLVLGWRD PVNRDYAAKL IVAFLITAIL GLVVKKLGFE LPETATPIAW ALIIGGIWMI 

       130        140        150        160        170        180 
FAEWAAARRP PHKEITWLVA ILVGIAQIVA GVFPGTSRSG ATIFVAMLAG TGNRASATEF 

       190        200        210        220        230        240 
AFLVGIPTMY AASAYELLKT FRDGGAAGED WTALGIAFVV STVVAFIAVK WLLAYIRSNR 

       250        260 
FTLFAIYRII LGVLLLGMAA TGLIA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM236080 Genomic DNA. Translation: CAK05818.1.
RefSeqYP_765934.1. NC_008380.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING216596.RL0328.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAK05818; CAK05818; RL0328.
GeneID4401068.
KEGGrle:RL0328.
PATRIC23137033. VBIRhiLeg32091_1468.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218356.
KOK06153.
OMAAQCFALI.
OrthoDBEOG6QP13M.
ProtClustDBPRK00281.

Enzyme and pathway databases

BioCycRLEG216596:GKE5-342-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUPPP_RHIL3
AccessionPrimary (citable) accession number: Q1MMI4
Entry history
Integrated into UniProtKB/Swiss-Prot: September 19, 2006
Last sequence update: May 30, 2006
Last modified: February 19, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families