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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Rhizobium leguminosarum bv. viciae (strain 3841)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. Pyrophosphate--fructose 6-phosphate 1-phosphotransferase (pfp)
  4. Fructose-1,6-bisphosphate aldolase (pRL120196), Fructose-bisphosphate aldolase (RL4012)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei346Proton donorUniRule annotation1
Active sitei377UniRule annotation1
Active sitei506UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:RL0504
OrganismiRhizobium leguminosarum bv. viciae (strain 3841)
Taxonomic identifieri216596 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
Proteomesi
  • UP000006575 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002526361 – 541Glucose-6-phosphate isomeraseAdd BLAST541

Interactioni

Protein-protein interaction databases

STRINGi216596.RL0504

Structurei

3D structure databases

ProteinModelPortaliQ1MM06
SMRiQ1MM06
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QP8 Bacteria
COG0166 LUCA
HOGENOMiHOG000261370
KOiK01810
OrthoDBiPOG091H04C3

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
Gene3Di1.10.1390.10, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR023096 G6P_Isomerase_C
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q1MM06-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNAIVEQLKS TADATKATDI RAAFAADSQR FSRFSVSLDD LLMDFSKTAV
60 70 80 90 100
NDDILKLLVK LAEEGGVEKK REEMFSGKAI NFTEDRAVLH TALRNRSNAP
110 120 130 140 150
VLVDGKDVMP DVNAVLAAMG KFADDVRSGT LKGATGKAIT DVVNIGIGGS
160 170 180 190 200
DLGPVMATLA LAPFHDGPRA HFVSNIDGAH IADILKLVQP ETTLFIVASK
210 220 230 240 250
TFTTVETMTN AQTARNFIAK ALGEAAVQHH FAAVSTALDK VAAFGIDSAR
260 270 280 290 300
VFGFWDWVGG RYSIWSAIGL PLMIAVGPEN FGKFLDGAHA VDNHFRKAPI
310 320 330 340 350
TENLPILLGL IGFYHRNVLG YPTRAILPYD QRLSRFPAYL QQLDMESNGK
360 370 380 390 400
GVTIDGTPVE GNSGPVVWGE PGTNGQHAFY QLIHQGTSII PAEFMIAANA
410 420 430 440 450
FEPELRHQHQ LLISNVLAQS EALMKGRTFA EAKKQLTDKG MDDKKADFIA
460 470 480 490 500
PHRVFTGNRP SITFVYDKLT PYALGRLIAL YEHRVFVEGV LFRINSFDQW
510 520 530 540
GVELGKELAT GLLPVVEGKE SAASHDSSTQ GLVAALAKLA K
Length:541
Mass (Da):58,599
Last modified:October 17, 2006 - v2
Checksum:i19FC9606341889BA
GO

Sequence cautioni

The sequence CAK05997 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM236080 Genomic DNA Translation: CAK05997.1 Different initiation.
RefSeqiWP_028740477.1, NC_008380.1

Genome annotation databases

EnsemblBacteriaiCAK05997; CAK05997; RL0504
KEGGirle:RL0504

Similar proteinsi

Entry informationi

Entry nameiG6PI_RHIL3
AccessioniPrimary (citable) accession number: Q1MM06
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: October 17, 2006
Last modified: June 20, 2018
This is version 71 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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