Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Rhizobium leguminosarum bv. viciae (strain 3841)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei346 – 3461Proton donorUniRule annotation
Active sitei377 – 3771UniRule annotation
Active sitei506 – 5061UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciRLEG216596:GKE5-522-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:RL0504
OrganismiRhizobium leguminosarum bv. viciae (strain 3841)
Taxonomic identifieri216596 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
ProteomesiUP000006575 Componenti: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 541541Glucose-6-phosphate isomerasePRO_0000252636Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi216596.RL0504.

Structurei

3D structure databases

ProteinModelPortaliQ1MM06.
SMRiQ1MM06. Positions 7-539.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1MM06-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNAIVEQLKS TADATKATDI RAAFAADSQR FSRFSVSLDD LLMDFSKTAV
60 70 80 90 100
NDDILKLLVK LAEEGGVEKK REEMFSGKAI NFTEDRAVLH TALRNRSNAP
110 120 130 140 150
VLVDGKDVMP DVNAVLAAMG KFADDVRSGT LKGATGKAIT DVVNIGIGGS
160 170 180 190 200
DLGPVMATLA LAPFHDGPRA HFVSNIDGAH IADILKLVQP ETTLFIVASK
210 220 230 240 250
TFTTVETMTN AQTARNFIAK ALGEAAVQHH FAAVSTALDK VAAFGIDSAR
260 270 280 290 300
VFGFWDWVGG RYSIWSAIGL PLMIAVGPEN FGKFLDGAHA VDNHFRKAPI
310 320 330 340 350
TENLPILLGL IGFYHRNVLG YPTRAILPYD QRLSRFPAYL QQLDMESNGK
360 370 380 390 400
GVTIDGTPVE GNSGPVVWGE PGTNGQHAFY QLIHQGTSII PAEFMIAANA
410 420 430 440 450
FEPELRHQHQ LLISNVLAQS EALMKGRTFA EAKKQLTDKG MDDKKADFIA
460 470 480 490 500
PHRVFTGNRP SITFVYDKLT PYALGRLIAL YEHRVFVEGV LFRINSFDQW
510 520 530 540
GVELGKELAT GLLPVVEGKE SAASHDSSTQ GLVAALAKLA K
Length:541
Mass (Da):58,599
Last modified:October 16, 2006 - v2
Checksum:i19FC9606341889BA
GO

Sequence cautioni

The sequence CAK05997.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM236080 Genomic DNA. Translation: CAK05997.1. Different initiation.
RefSeqiYP_766113.1. NC_008380.1.

Genome annotation databases

EnsemblBacteriaiCAK05997; CAK05997; RL0504.
KEGGirle:RL0504.
PATRICi23137415. VBIRhiLeg32091_1658.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM236080 Genomic DNA. Translation: CAK05997.1. Different initiation.
RefSeqiYP_766113.1. NC_008380.1.

3D structure databases

ProteinModelPortaliQ1MM06.
SMRiQ1MM06. Positions 7-539.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi216596.RL0504.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAK05997; CAK05997; RL0504.
KEGGirle:RL0504.
PATRICi23137415. VBIRhiLeg32091_1658.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
BioCyciRLEG216596:GKE5-522-MONOMER.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 3841.

Entry informationi

Entry nameiG6PI_RHIL3
AccessioniPrimary (citable) accession number: Q1MM06
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 16, 2006
Last sequence update: October 16, 2006
Last modified: March 31, 2015
This is version 55 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.