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Q1MM06 (G6PI_RHIL3) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:RL0504
OrganismRhizobium leguminosarum bv. viciae (strain 3841) [Complete proteome] [HAMAP]
Taxonomic identifier216596 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium

Protein attributes

Sequence length541 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Sequence caution

The sequence CAK05997.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 541541Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000252636

Sites

Active site3461Proton donor By similarity
Active site3771 By similarity
Active site5061 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q1MM06 [UniParc].

Last modified October 17, 2006. Version 2.
Checksum: 19FC9606341889BA

FASTA54158,599
        10         20         30         40         50         60 
MNAIVEQLKS TADATKATDI RAAFAADSQR FSRFSVSLDD LLMDFSKTAV NDDILKLLVK 

        70         80         90        100        110        120 
LAEEGGVEKK REEMFSGKAI NFTEDRAVLH TALRNRSNAP VLVDGKDVMP DVNAVLAAMG 

       130        140        150        160        170        180 
KFADDVRSGT LKGATGKAIT DVVNIGIGGS DLGPVMATLA LAPFHDGPRA HFVSNIDGAH 

       190        200        210        220        230        240 
IADILKLVQP ETTLFIVASK TFTTVETMTN AQTARNFIAK ALGEAAVQHH FAAVSTALDK 

       250        260        270        280        290        300 
VAAFGIDSAR VFGFWDWVGG RYSIWSAIGL PLMIAVGPEN FGKFLDGAHA VDNHFRKAPI 

       310        320        330        340        350        360 
TENLPILLGL IGFYHRNVLG YPTRAILPYD QRLSRFPAYL QQLDMESNGK GVTIDGTPVE 

       370        380        390        400        410        420 
GNSGPVVWGE PGTNGQHAFY QLIHQGTSII PAEFMIAANA FEPELRHQHQ LLISNVLAQS 

       430        440        450        460        470        480 
EALMKGRTFA EAKKQLTDKG MDDKKADFIA PHRVFTGNRP SITFVYDKLT PYALGRLIAL 

       490        500        510        520        530        540 
YEHRVFVEGV LFRINSFDQW GVELGKELAT GLLPVVEGKE SAASHDSSTQ GLVAALAKLA 


K 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM236080 Genomic DNA. Translation: CAK05997.1. Different initiation.
RefSeqYP_766113.1. NC_008380.1.

3D structure databases

ProteinModelPortalQ1MM06.
SMRQ1MM06. Positions 7-539.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING216596.RL0504.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAK05997; CAK05997; RL0504.
GeneID4402124.
KEGGrle:RL0504.
PATRIC23137415. VBIRhiLeg32091_1658.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261370.
KOK01810.
OrthoDBEOG64R61J.
ProtClustDBPRK00179.

Enzyme and pathway databases

BioCycRLEG216596:GKE5-522-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_RHIL3
AccessionPrimary (citable) accession number: Q1MM06
Entry history
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: October 17, 2006
Last modified: February 19, 2014
This is version 49 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways