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Protein

60 kDa chaperonin 1

Gene

groL1

Organism
Rhizobium leguminosarum bv. viciae (strain 3841)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperonin 1UniRule annotation
Alternative name(s):
GroEL protein 1UniRule annotation
Protein Cpn60 1UniRule annotation
Gene namesi
Name:groL1UniRule annotation
Synonyms:groEL1UniRule annotation
Ordered Locus Names:RL0883
OrganismiRhizobium leguminosarum bv. viciae (strain 3841)
Taxonomic identifieri216596 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
Proteomesi
  • UP000006575 Componenti: Chromosome

Subcellular locationi

Q1MKX4:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002569611 – 54760 kDa chaperonin 1Add BLAST547

Proteomic databases

PRIDEiQ1MKX4.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Protein-protein interaction databases

STRINGi216596.RL0883.

Structurei

3D structure databases

ProteinModelPortaliQ1MKX4.
SMRiQ1MKX4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9. Bacteria.
COG0459. LUCA.
HOGENOMiHOG000076290.
KOiK04077.
OMAiTDTDKME.
OrthoDBiPOG091H00E7.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
IPR027410. TCP-1-like_intermed.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
SSF54849. SSF54849. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1MKX4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASKEIKFGR TAREKMLRGV DILADAVKVT LGPKGRNVII DKSFGAPRIT
60 70 80 90 100
KDGVSVAKEI ELEDKFENMG AQMVREVASK TNDIAGDGTT TATVLAQAIV
110 120 130 140 150
REGNKAVAAG MNPMDLKRGI DLAVADVVKD LQAKAKKIST SEEVAQVGTI
160 170 180 190 200
SANGDKQVGL DIAEAMQKVG NEGVITVEEA KTAETELEVV EGMQFDRGYL
210 220 230 240 250
SPYFVTNPEK MIADLEDVFI LLHEKKLSNL QSMLPVLEAV VQTGKPLLIV
260 270 280 290 300
AEDVEGEALA TLVVNKLRGG LKIAAVKAPG FGDRRKAMLE DIAILTGGTV
310 320 330 340 350
ISEDLGIKLE SVTLDMLGRA KKVSISKENT TIVDGSGAKT DIEGRVAQIK
360 370 380 390 400
AQIEETTSDY DREKLQERLA KLAGGVAVIR VGGSTEVEVK EKKDRIDDAL
410 420 430 440 450
NATRAAVQEG IVPGGGIALL RSSTKITVKG ANDDQEAGIN IVRRALQSLV
460 470 480 490 500
RQIAENAGDE ASIVVGKVLD KNEDNFGYNA QTSEYGDMIA MGIVDPLKVV
510 520 530 540
RTALQNAASV ASLLITTEAM IAELPKKESA GGGMPGGMGG MGGMDMM
Length:547
Mass (Da):57,902
Last modified:May 30, 2006 - v1
Checksum:i1DF49BB81FA5FEE1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM236080 Genomic DNA. Translation: CAK06380.1.
RefSeqiWP_003545786.1. NC_008380.1.

Genome annotation databases

EnsemblBacteriaiCAK06380; CAK06380; RL0883.
KEGGirle:RL0883.

Similar proteinsi

Entry informationi

Entry nameiCH601_RHIL3
AccessioniPrimary (citable) accession number: Q1MKX4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: May 30, 2006
Last modified: October 25, 2017
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families