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Reviewed, UniProtKB/Swiss-Prot Q1MJU4 (BETA_RHIL3)

Last modified June 16, 2009. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Choline dehydrogenase
      Short name=CHD
      Short name=CDH
    EC=1.1.99.1
Gene names
Name: betA
Ordered Locus Names: RL1270
OrganismRhizobium leguminosarum bv. viciae (strain 3841) [Complete proteome] [HAMAP]
Taxonomic identifier216596 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Rhizobium

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Protein attributes

Sequence length549 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Function

Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine By similarity.

Catalytic activity

Choline + acceptor = betaine aldehyde + reduced acceptor. HAMAP MF_00750

Cofactor

FAD By similarity.

Pathway

Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1. HAMAP MF_00750

Sequence similarities

Belongs to the GMC oxidoreductase family.

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 549549Choline dehydrogenase HAMAP MF_00750
PRO_0000258933

Regions

Nucleotide binding4 – 3330FAD Probable

Sites

Active site4651 By similarity

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Sequences

Sequence LengthMass (Da)Tools
Q1MJU4-1 [UniParc].

Last modified May 30, 2006. Version 1.
Checksum: BC54B99E2B9A6912

FASTA54960,299
        10         20         30         40         50         60 
MQADFVIIGS GSAGSALAYR LSEGGKNSVI VIEAGGSDFG PFIQMPAALA WPMSMKRYNW 

        70         80         90        100        110        120 
GYLSEPEANL NNRRITAPRG KVIGGSSSIN GMVYVRGHAE DFNRWEELGA SGWAYADVLP 

       130        140        150        160        170        180 
YFKRMEHSHG GEEGWRGTDG PLHVQRGGFT NPLFQAFVEA GKQAGFETTE DYNGSKQEGF 

       190        200        210        220        230        240 
GLMEQTIFGG RRWSAANAYL KPALKRDNVK IVYGLAQRIV IEDGRATGVE IERNGRIEVV 

       250        260        270        280        290        300 
KANREVIVSA SSFNSPKLLM LSGIGPGQHL QDMGIAVKAD RPGVGANLQD HMEFYFQQVS 

       310        320        330        340        350        360 
TKPVSLYSWL PWFWQGVAGA QWLLSRGGLG ASNQFEACAF LRSAPGLKQP DIQYHFLPVA 

       370        380        390        400        410        420 
ISYDGKAAAK SHGFQVHVGY NLSKSRGSVS LRSADPKADP VLRFNYMSHA EDWEKFRHCV 

       430        440        450        460        470        480 
RLTREIFGQS AFHDYRGPEI QPGEGVQSDE EIDAFLREHL ESAYHPCGTC RMGAKDDPMA 

       490        500        510        520        530        540 
VVDPQTRVIG IDGLRVADSS IFPHVTYGNL NGPSIMTGEK AADHILGKQP LARSNQEPWI 


NPRAAVSDR

« Hide

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Cross-references

Sequence databases

AM236080 Genomic DNA. Translation: CAK06766.1.
RefSeqYP_766875.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID4399360.
GenomeReviewsGene locus RL1270 in contig AM236080_GR.
KEGGrle:RL1270.
NMPDRfig|216596.1.peg.1323.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ1MJU4.
OMAQ1MJU4. DMGIAVK.

Family and domain databases

HAMAPMF_00750.
[Tree]
InterProIPR011533. Choline_dehydrogenase.
IPR012132. GMC_OxRdtase.
IPR000172. GMC_OxRdtase_N.
IPR007867. GMC_OxRtase_C.
[Graphical view]
PfamPF05199. GMC_oxred_C. 1 hit.
PF00732. GMC_oxred_N. 1 hit.
[Graphical view]
PIRSFPIRSF000137. Alcohol_oxidase. 1 hit.
TIGRFAMsTIGR01810. betA. 1 hit.
PROSITEPS00623. GMC_OXRED_1. 1 hit.
PS00624. GMC_OXRED_2. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameBETA_RHIL3
AccessionPrimary (citable) accession number: Q1MJU4
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: May 30, 2006
Last modified: June 16, 2009
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents