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Protein

Guanylate kinase

Gene

gmk

Organism
Rhizobium leguminosarum bv. viciae (strain 3841)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi22 – 29ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:RL1563
OrganismiRhizobium leguminosarum bv. viciae (strain 3841)
Taxonomic identifieri216596 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
Proteomesi
  • UP000006575 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002663801 – 220Guanylate kinaseAdd BLAST220

Interactioni

Protein-protein interaction databases

STRINGi216596.RL1563.

Structurei

3D structure databases

ProteinModelPortaliQ1MJ02.
SMRiQ1MJ02.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 194Guanylate kinase-likeUniRule annotationAdd BLAST180

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UHA. Bacteria.
COG0194. LUCA.
HOGENOMiHOG000037638.
KOiK00942.
OMAiAGNYYGT.
OrthoDBiPOG091H01Q4.

Family and domain databases

HAMAPiMF_00328. Guanylate_kinase. 1 hit.
InterProiView protein in InterPro
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR017665. Guanylate_kinase.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00625. Guanylate_kin. 1 hit.
SMARTiView protein in SMART
SM00072. GuKc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
PROSITEiView protein in PROSITE
PS50052. GUANYLATE_KINASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1MJ02-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKPAKSSPVQ IARRGLMLVI SSPSGAGKST IARTLLETDR QIGLSVSVTT
60 70 80 90 100
RQRRPSEVED VHYHFKSVRE FERLRDSDAL LEWAEVHGNF YGTPREPVEQ
110 120 130 140 150
AMGEGRDMLF DIDWQGAQQL QEKMSADVVS IFVLPPTMTE LQSRLHRRAE
160 170 180 190 200
DSEEVIQTRL ANSRAEIAHW REYDYVIVND DLNAALDAVQ SIVKAERLRR
210 220
DRRHGMFDFV RELLEETPSL
Length:220
Mass (Da):25,232
Last modified:May 30, 2006 - v1
Checksum:iD761518746EDB1D5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM236080 Genomic DNA. Translation: CAK07058.1.
RefSeqiWP_003547062.1. NC_008380.1.

Genome annotation databases

EnsemblBacteriaiCAK07058; CAK07058; RL1563.
KEGGirle:RL1563.

Similar proteinsi

Entry informationi

Entry nameiKGUA_RHIL3
AccessioniPrimary (citable) accession number: Q1MJ02
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: May 30, 2006
Last modified: March 28, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome