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Q1MIE3 (EFTU_RHIL3) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Elongation factor Tu

Short name=EF-Tu
Gene names
Name:tuf1
Synonyms:tufB1
Ordered Locus Names:RL1757
AND
Name:tuf2
Synonyms:tufB2
Ordered Locus Names:RL1772
OrganismRhizobium leguminosarum bv. viciae (strain 3841) [Complete proteome] [HAMAP]
Taxonomic identifier216596 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium

Protein attributes

Sequence length391 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. HAMAP-Rule MF_00118

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00118

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00118.

Sequence similarities

Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandGTP-binding
Nucleotide-binding
   Molecular functionElongation factor
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionGTP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

GTPase activity

Inferred from electronic annotation. Source: InterPro

translation elongation factor activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 391391Elongation factor Tu HAMAP-Rule MF_00118
PRO_0000337488

Regions

Nucleotide binding19 – 268GTP By similarity
Nucleotide binding76 – 805GTP By similarity
Nucleotide binding131 – 1344GTP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q1MIE3 [UniParc].

Last modified May 30, 2006. Version 1.
Checksum: A2EFB46A6FA4711D

FASTA39142,594
        10         20         30         40         50         60 
MGKSKFERNK PHVNIGTIGH VDHGKTSLTA AITKYFGEYK AYDQIDAAPE EKARGITIST 

        70         80         90        100        110        120 
AHVEYETPAR HYAHVDCPGH ADYVKNMITG AAQMDGAILV CSAADGPMPQ TREHILLARQ 

       130        140        150        160        170        180 
VGVPAIVVFL NKVDQVDDAE LLELVELEVR ELLSSYDFPG DDIPIIKGSA LAALEDSDKK 

       190        200        210        220        230        240 
IGEDAIRELM AAVDAYIPTP ERPINLPFLL PIEDVFSISG RGTVVTGRVE RGIVKVGEEV 

       250        260        270        280        290        300 
EIVGIRPTTK TTVTGVEMFR KLLDQGQAGD NIGALIRGVT RDGVERGQIL CKPGSVKPHK 

       310        320        330        340        350        360 
KFMAEAYILT KEEGGRHTPF FTNYRPQFYF RTTDVTGIVT LPEGTEMVMP GDNVTVSVEL 

       370        380        390 
IVPIAMEEKL RFAIREGGRT VGAGIVASIV E 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM236080 Genomic DNA. Translation: CAK07252.1.
AM236080 Genomic DNA. Translation: CAK07267.1.
RefSeqYP_767361.1. NC_008380.1.
YP_767376.1. NC_008380.1.

3D structure databases

ProteinModelPortalQ1MIE3.
SMRQ1MIE3. Positions 2-390.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING216596.RL1772.

Proteomic databases

PRIDEQ1MIE3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAK07252; CAK07252; RL1757.
CAK07267; CAK07267; RL1772.
GeneID4401281.
4401282.
KEGGrle:RL1757.
rle:RL1772.
PATRIC23140099. VBIRhiLeg32091_2984.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0050.
HOGENOMHOG000229290.
KOK02358.
OMADNIEMVG.
OrthoDBEOG6R5C6X.

Enzyme and pathway databases

BioCycRLEG216596:GKE5-1796-MONOMER.
RLEG216596:GKE5-1812-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00118_B. EF_Tu_B.
InterProIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSPR00315. ELONGATNFCT.
SUPFAMSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEFTU_RHIL3
AccessionPrimary (citable) accession number: Q1MIE3
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 30, 2006
Last modified: May 14, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families