Q1MI52HGD_RHIJ3Homogentisate 1,2-dioxygenaseHGDO1.13.11.5Homogentisate oxygenaseHomogentisic acid oxidaseHomogentisicasehmgARL1864Rhizobium johnstonii (strain DSM 114642 / LMG 32736 / 3841)Rhizobium leguminosarum bv. viciaeBacteriaPseudomonadotaAlphaproteobacteriaHyphomicrobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobiumRhizobium johnstoniiThe genome of Rhizobium leguminosarum has recognizable core and accessory components.NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.homogentisate + O2 = 4-maleylacetoacetate + H(+)Fe cationAmino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 4/6.Hexamer; dimer of trimers.Belongs to the homogentisate dioxygenase family.DioxygenaseIronMetal-bindingOxidoreductasePhenylalanine catabolismTyrosine catabolismFe cationFe cationhomogentisateFe cationhomogentisateMDQTSIQTSDGEAATANTLKYMPGFGNDFETESLPGALPQGQNSPQKCNYGLYAEQLSGSPFTAPRGTNERSWLYRIRPSVRHTRRFSNASYPLWKTAPCLDEHSLPLGQLRWDPIPAPAERLTFLEGVRTITTAGDAATQVGMSAHAYVFNEDMVDDYFFNADGELLIVPQLGAIRVFTEMGIMDVEPLEICLIPRGMMFKILKSGEQTVWRGYICENYGAKFTLPDRGPIGANCLANPRDFKTPVAAFEDKETPCRVHVKWCGKFYVTEIGHSPLDVVAWHGNYAPFKYDLRTFSPVGAIRFDHPDPSIFSVLTAPSEDAGTANVDFVIFPPRWLVAEHTFRPPWYHRNIMSEFMGLIHGQYDAKEEGFVPGGISLHNMMLPHGPDALAFEKASNTELKPVKLDHTMAFMFETRYAQQLTKYAAELETLQDNYLECWDGLERKFDGTPGIK
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