ID   Q1MGI8_RHIJ3            Unreviewed;      1084 AA.
AC   Q1MGI8;
DT   30-MAY-2006, integrated into UniProtKB/TrEMBL.
DT   30-MAY-2006, sequence version 1.
DT   27-MAR-2024, entry version 100.
DE   SubName: Full=Adenylate cyclase {ECO:0000313|EMBL:CAK07932.1};
DE            EC=4.6.1.1 {ECO:0000313|EMBL:CAK07932.1};
GN   OrderedLocusNames=RL2441 {ECO:0000313|EMBL:CAK07932.1};
OS   Rhizobium johnstonii (strain DSM 114642 / LMG 32736 / 3841) (Rhizobium
OS   leguminosarum bv. viciae).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium;
OC   Rhizobium johnstonii.
OX   NCBI_TaxID=216596 {ECO:0000313|EMBL:CAK07932.1, ECO:0000313|Proteomes:UP000006575};
RN   [1] {ECO:0000313|EMBL:CAK07932.1, ECO:0000313|Proteomes:UP000006575}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=3841 {ECO:0000313|EMBL:CAK07932.1,
RC   ECO:0000313|Proteomes:UP000006575};
RX   PubMed=16640791; DOI=10.1186/gb-2006-7-4-r34;
RA   Young J.W., Crossman L.C., Johnston A.W.B., Thomson N.R., Ghazoui Z.F.,
RA   Hull K.H., Wexler M., Curson A.R.J., Todd J.D., Poole P.S., Mauchline T.H.,
RA   East A.K., Quail M.A., Churcher C., Arrowsmith C., Cherevach A.,
RA   Chillingworth T., Clarke K., Cronin A., Davis P., Fraser A., Hance Z.,
RA   Hauser H., Jagels K., Moule S., Mungall K., Norbertczak H.,
RA   Rabbinowitsch E., Sanders M., Simmonds M., Whitehead S., Parkhill J.;
RT   "The genome of Rhizobium leguminosarum has recognizable core and accessory
RT   components.";
RL   Genome Biol. 7:R34.1-R34.20(2006).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AM236080; CAK07932.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q1MGI8; -.
DR   EnsemblBacteria; CAK07932; CAK07932; RL2441.
DR   KEGG; rle:RL2441; -.
DR   eggNOG; COG2114; Bacteria.
DR   eggNOG; COG2888; Bacteria.
DR   eggNOG; COG3899; Bacteria.
DR   HOGENOM; CLU_004435_0_1_5; -.
DR   Proteomes; UP000006575; Chromosome.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR025874; DZR.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR16305:SF28; ADENYLATE CYCLASE 10; 1.
DR   PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF12773; DZR; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   Pfam; PF13424; TPR_12; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SMART; SM00028; TPR; 6.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 2.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000313|EMBL:CAK07932.1};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          81..213
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   1084 AA;  118109 MW;  1C921A4631B9CE7E CRC64;
     MRPMECSGCG FDIQSGFAFC PRCGARQPVT CAACGNPCQP DFAFCPACGA SIPSKVQAAS
     KPKIEAVPSK SEGDADRRPV TVLFADLCGF TTLSEQIDPE VMRVLQNELF EEMTQAVEAY
     GGFVDKFVGD ALLALFGAPV AHEDDPVRAL GAALDMIGRA TQVGERWHAR AGVPLRLHIG
     INSGPVVTGG FGAVSTKSYS VTGDTVNTAQ RLQSMAGEND ILVGPLTYRL TRHAFAFESL
     GAQALRGKSG NVLVHRLTGL SEAPHTARGL ESFGLQAPMI GRDTEMSRLL TCLDLACGGA
     AQLVRLIGEA GIGKSRLVNE FVAIASNAAR FQGLAIRKAT CSPLGEQSYG TLGAVVRSAY
     GIGERDDLDR ARQLLATGFR ALDLTQEDVE GLLPLFLHVL GLGDPDGALR YIEPEQLRRQ
     IFYAVRTVFE RRLAQGPLLL VIEDLHWADA ASLEVLRFMM DRLERSRLML LAVYRPTSQT
     DPLDSNRVSV TVQRLAPLFA ADGQKLLAAF FGESYAKLPV TMRKRILDRA GGNPLFIEET
     LRALIDMGTL HNDGQRWHVA AEDTDVDIPL NLQALLLARV DRLPQDIRRL AQEAAVVGPK
     FDTALLRTIA TDPAAIDAAL DHLCDANIIE ELRGPDAGGS PGYRFSQTLM HDVIYHNLLL
     QRRMELHRRV GQVLERQYGA APDRPEHLAQ LGHHFSLTTE KAKGATYLMA AGDLARKAYA
     NDDAMRLYRQ ALAAFATEAE VTPEQQALLE RLADLCGPAG LRDAALNHYQ RALAIHRTKD
     DPIAAARILR KIGRLHLDAG RRDQAETHLA EAEAMIATID APVERAHVLQ ERGHLAFRMG
     DQAAAAEWAT QALQCLQTLP IDGTTEAGRE TARAMAEALN TKGAAFARLG RRREAVQEVE
     RSLSVAEKAD LQSAACRAYS NLGVLYTIVD PANAIRICRR GLEVATRIGD LGFQARLLAN
     LAVACCTFTD RCAAEGVPAA EKAVEIDRAL DQRDHLSVPL IVLGQIHQCR GQPKLARKYY
     EEALEVAKEI DEPQLLFPCY DGLATLSLEH DDMDEAERYF TLAQDVCIRH NLDPGTLVVL
     PFLD
//