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Q1MGA4 (Q1MGA4_RHIL3) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
GTP cyclohydrolase 1 1 HAMAP MF_00223

EC=3.5.4.16 HAMAP MF_00223
Alternative name(s):
GTP cyclohydrolase I 1 HAMAP MF_00223
Gene names
Name:folE EMBL CAK08019.1
Synonyms:folE1 HAMAP MF_00223
Ordered Locus Names:RL2531
OrganismRhizobium leguminosarum bv. viciae (strain 3841) [Complete proteome] [HAMAP]
Taxonomic identifier216596 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium

Protein attributes

Sequence length204 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate. HAMAP MF_00223 SAAS SAAS001474

Pathway

Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1. HAMAP MF_00223 SAAS SAAS001474

Subunit structure

Homopolymer By similarity. HAMAP MF_00223

Sequence similarities

Belongs to the GTP cyclohydrolase I family. HAMAP MF_00223

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding941Zinc By similarity HAMAP MF_00223
Metal binding971Zinc By similarity HAMAP MF_00223
Metal binding1651Zinc By similarity HAMAP MF_00223

Sequences

Sequence LengthMass (Da)Tools
Q1MGA4 [UniParc].

Last modified May 30, 2006. Version 1.
Checksum: AE628CB2A6D75C01

FASTA20422,943
        10         20         30         40         50         60 
MDAIVKNFPQ TTRDSDRPSQ QEAEEAVRVL LRWAGDDPTR EGLLETPARV VKSYRELFSG 

        70         80         90        100        110        120 
YDMAAEDVLG RTFEEVAGYD DMVLVKDIPF YSHCEHHMVP IIGKAHVAYM PDGRVLGLSK 

       130        140        150        160        170        180 
IARVVEIYGR RLQTQETMTA QIARAIDDTL NPRGVAVLIE AEHMCMAMRG VQKQGSTTLT 

       190        200 
TTFTGTFKTE PADQARFMTM VRSR 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM236080 Genomic DNA. Translation: CAK08019.1.
RefSeqYP_768115.1. NC_008380.1.

3D structure databases

ProteinModelPortalQ1MGA4.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ1MGA4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4402192.
GenomeReviewsGene locus RL2531 in contig AM236080_GR.
KEGGrle:RL2531.
NMPDRfig|216596.1.peg.2616.
PATRIC23141693. VBIRhiLeg32091_3769.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0302.
HOGENOMHBG370191.
OMACEAKHLC.
PhylomeDBQ1MGA4.
ProtClustDBPRK09347.

Enzyme and pathway databases

BioCycRLEG216596:RL2531-MONOMER.

Family and domain databases

HAMAPMF_00223. FolE.
[Tree]
InterProIPR001474. GTP_CycHdrlase_I.
IPR020602. GTP_CycHdrlase_I/CN_OxRdtase.
IPR018234. GTP_CycHdrlase_I_CS.
[Graphical view]
KOK01495.
PANTHERPTHR11109. GTP_cyclohydro_I. 1 hit.
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
TIGRFAMsTIGR00063. FolE. 1 hit.
PROSITEPS00859. GTP_CYCLOHYDROL_1_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ1MGA4_RHIL3
AccessionPrimary (citable) accession number: Q1MGA4
Entry history
Integrated into UniProtKB/TrEMBL: May 30, 2006
Last sequence update: May 30, 2006
Last modified: December 14, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)