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Q1MG12

- GLSA_RHIL3

UniProt

Q1MG12 - GLSA_RHIL3

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Protein

Glutaminase

Gene
glsA, RL2623
Organism
Rhizobium leguminosarum bv. viciae (strain 3841)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei64 – 641Substrate By similarity
Binding sitei114 – 1141Substrate By similarity
Binding sitei160 – 1601Substrate By similarity
Binding sitei167 – 1671Substrate By similarity
Binding sitei191 – 1911Substrate By similarity
Binding sitei243 – 2431Substrate By similarity
Binding sitei261 – 2611Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciRLEG216596:GKE5-2670-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:RL2623
OrganismiRhizobium leguminosarum bv. viciae (strain 3841)
Taxonomic identifieri216596 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
ProteomesiUP000006575: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 309309GlutaminaseUniRule annotationPRO_1000048348Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi216596.RL2623.

Structurei

3D structure databases

ProteinModelPortaliQ1MG12.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiQRARRIN.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1MG12-1 [UniParc]FASTAAdd to Basket

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MADLQATLDS IYADIQPRIG EGKVADYIPE LAKVDPQQFG MAIVTVDGKV    50
YRVGNADTAF SIQSISKVFM LTLALGKVGE GLWKRVGREP SGSAFNSIVQ 100
LEHESGIPRN PFINAGAIAV SDVVMAGHAP REAIGELLRF VRYLADDESI 150
TIDDKVARSE TQTGYRNFAL ANFMRAYRNL DHPVDHVLGV YFHQCALSMS 200
CEQLARAGLF LAARGSNPTT GHSVVSPKRA RRINALMLTC GHYDGSGDFA 250
YHVGLPGKSG VGGGIFAVAP GIASIAVWSP GLNKVGNSQL GAAALEMLAA 300
RTGWSVFGD 309
Length:309
Mass (Da):32,925
Last modified:May 30, 2006 - v1
Checksum:iF8A496BEAD38E959
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM236080 Genomic DNA. Translation: CAK08111.1.
RefSeqiYP_768207.1. NC_008380.1.

Genome annotation databases

EnsemblBacteriaiCAK08111; CAK08111; RL2623.
GeneIDi4400636.
KEGGirle:RL2623.
PATRICi23141899. VBIRhiLeg32091_3871.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM236080 Genomic DNA. Translation: CAK08111.1 .
RefSeqi YP_768207.1. NC_008380.1.

3D structure databases

ProteinModelPortali Q1MG12.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 216596.RL2623.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAK08111 ; CAK08111 ; RL2623 .
GeneIDi 4400636.
KEGGi rle:RL2623.
PATRICi 23141899. VBIRhiLeg32091_3871.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi QRARRIN.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci RLEG216596:GKE5-2670-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 3841.

Entry informationi

Entry nameiGLSA_RHIL3
AccessioniPrimary (citable) accession number: Q1MG12
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 30, 2006
Last modified: May 14, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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