Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q1MEZ8

- ASSY1_RHIL3

UniProt

Q1MEZ8 - ASSY1_RHIL3

Protein

Argininosuccinate synthase 1

Gene

argG1

Organism
Rhizobium leguminosarum bv. viciae (strain 3841)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 1 (30 May 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)-(L-arginino)succinate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei37 – 371ATP; via amide nitrogen and carbonyl oxygenUniRule annotation
    Binding sitei88 – 881CitrullineUniRule annotation
    Binding sitei93 – 931CitrullineUniRule annotation
    Binding sitei118 – 1181ATP; via amide nitrogenUniRule annotation
    Binding sitei120 – 1201AspartateUniRule annotation
    Binding sitei124 – 1241AspartateUniRule annotation
    Binding sitei124 – 1241CitrullineUniRule annotation
    Binding sitei125 – 1251AspartateUniRule annotation
    Binding sitei128 – 1281CitrullineUniRule annotation
    Binding sitei179 – 1791CitrullineUniRule annotation
    Binding sitei188 – 1881CitrullineUniRule annotation
    Binding sitei264 – 2641CitrullineUniRule annotation
    Binding sitei276 – 2761CitrullineUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi10 – 189ATPUniRule annotation

    GO - Molecular functioni

    1. argininosuccinate synthase activity Source: UniProtKB-HAMAP
    2. ATP binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. arginine biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Ligase

    Keywords - Biological processi

    Amino-acid biosynthesis, Arginine biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciRLEG216596:GKE5-3035-MONOMER.
    UniPathwayiUPA00068; UER00113.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Argininosuccinate synthase 1UniRule annotation (EC:6.3.4.5UniRule annotation)
    Alternative name(s):
    Citrulline--aspartate ligase 1UniRule annotation
    Gene namesi
    Name:argG1UniRule annotation
    Ordered Locus Names:RL2987
    OrganismiRhizobium leguminosarum bv. viciae (strain 3841)
    Taxonomic identifieri216596 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
    ProteomesiUP000006575: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 403403Argininosuccinate synthase 1PRO_0000263961Add
    BLAST

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi216596.RL2987.

    Structurei

    3D structure databases

    ProteinModelPortaliQ1MEZ8.
    SMRiQ1MEZ8. Positions 6-395.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the argininosuccinate synthase family. Type 1 subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0137.
    HOGENOMiHOG000230093.
    KOiK01940.
    OMAiYAFPAIK.
    OrthoDBiEOG6K9QCV.

    Family and domain databases

    Gene3Di3.40.50.620. 1 hit.
    3.90.1260.10. 1 hit.
    HAMAPiMF_00005. Arg_succ_synth_type1.
    InterProiIPR001518. Arginosuc_synth.
    IPR018223. Arginosuc_synth_CS.
    IPR023434. Arginosuc_synth_type_1_subfam.
    IPR024074. AS_cat/multimer_dom_body.
    IPR014729. Rossmann-like_a/b/a_fold.
    [Graphical view]
    PfamiPF00764. Arginosuc_synth. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00032. argG. 1 hit.
    PROSITEiPS00564. ARGININOSUCCIN_SYN_1. 1 hit.
    PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q1MEZ8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTKIEKIVLS YSGGLDTSII LKWLQETYGC EVVTFTADLG QGEELEPARA    50
    KAEMSGVKDI RIVDLREEFV SDFVFPMLRA NALYEGQYLL GSSIARPLIA 100
    KHLVGIAREV GADAVAHGAT GKGNDQIRFE LAVNALDPSI KVIAPWRQWN 150
    IRSRLQLSEY AEKHRIPVPS DKRGEAPFSI DANLLHTSTE GKSLENPAEV 200
    APDHVYQRTV DPVDAPDTPE IITVGFERGD PVSVNGKAMT PAALLTELNG 250
    LGGRHGVGRL DLVENRFIGM KSRGIYETPG GTILLAAHRG IESITLDRAA 300
    AHLKDEIMPR YAELIYNGFW FAPEREMLQA LIDHSQAFVS GEVTLRLYKG 350
    SASVISRASP CSLYSADLVT FEESTIAFDH HDAEGFIRLN GLRLRSWAAR 400
    NGR 403
    Length:403
    Mass (Da):44,319
    Last modified:May 30, 2006 - v1
    Checksum:i4A143B783BBD0634
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM236080 Genomic DNA. Translation: CAK08476.1.
    RefSeqiYP_768571.1. NC_008380.1.

    Genome annotation databases

    EnsemblBacteriaiCAK08476; CAK08476; RL2987.
    GeneIDi4400740.
    KEGGirle:RL2987.
    PATRICi23142673. VBIRhiLeg32091_4258.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM236080 Genomic DNA. Translation: CAK08476.1 .
    RefSeqi YP_768571.1. NC_008380.1.

    3D structure databases

    ProteinModelPortali Q1MEZ8.
    SMRi Q1MEZ8. Positions 6-395.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 216596.RL2987.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAK08476 ; CAK08476 ; RL2987 .
    GeneIDi 4400740.
    KEGGi rle:RL2987.
    PATRICi 23142673. VBIRhiLeg32091_4258.

    Phylogenomic databases

    eggNOGi COG0137.
    HOGENOMi HOG000230093.
    KOi K01940.
    OMAi YAFPAIK.
    OrthoDBi EOG6K9QCV.

    Enzyme and pathway databases

    UniPathwayi UPA00068 ; UER00113 .
    BioCyci RLEG216596:GKE5-3035-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.620. 1 hit.
    3.90.1260.10. 1 hit.
    HAMAPi MF_00005. Arg_succ_synth_type1.
    InterProi IPR001518. Arginosuc_synth.
    IPR018223. Arginosuc_synth_CS.
    IPR023434. Arginosuc_synth_type_1_subfam.
    IPR024074. AS_cat/multimer_dom_body.
    IPR014729. Rossmann-like_a/b/a_fold.
    [Graphical view ]
    Pfami PF00764. Arginosuc_synth. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00032. argG. 1 hit.
    PROSITEi PS00564. ARGININOSUCCIN_SYN_1. 1 hit.
    PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 3841.

    Entry informationi

    Entry nameiASSY1_RHIL3
    AccessioniPrimary (citable) accession number: Q1MEZ8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 12, 2006
    Last sequence update: May 30, 2006
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3