ID   Q1ME67_RHIJ3            Unreviewed;       306 AA.
AC   Q1ME67;
DT   30-MAY-2006, integrated into UniProtKB/TrEMBL.
DT   30-MAY-2006, sequence version 1.
DT   27-MAR-2024, entry version 84.
DE   SubName: Full=Transmembrane adenylate/guanylate cyclase {ECO:0000313|EMBL:CAK08759.1};
DE            EC=4.6.1.1 {ECO:0000313|EMBL:CAK08759.1};
GN   Name=cyaA5 {ECO:0000313|EMBL:CAK08759.1};
GN   OrderedLocusNames=RL3271 {ECO:0000313|EMBL:CAK08759.1};
OS   Rhizobium johnstonii (strain DSM 114642 / LMG 32736 / 3841) (Rhizobium
OS   leguminosarum bv. viciae).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium;
OC   Rhizobium johnstonii.
OX   NCBI_TaxID=216596 {ECO:0000313|EMBL:CAK08759.1, ECO:0000313|Proteomes:UP000006575};
RN   [1] {ECO:0000313|EMBL:CAK08759.1, ECO:0000313|Proteomes:UP000006575}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=3841 {ECO:0000313|EMBL:CAK08759.1,
RC   ECO:0000313|Proteomes:UP000006575};
RX   PubMed=16640791; DOI=10.1186/gb-2006-7-4-r34;
RA   Young J.W., Crossman L.C., Johnston A.W.B., Thomson N.R., Ghazoui Z.F.,
RA   Hull K.H., Wexler M., Curson A.R.J., Todd J.D., Poole P.S., Mauchline T.H.,
RA   East A.K., Quail M.A., Churcher C., Arrowsmith C., Cherevach A.,
RA   Chillingworth T., Clarke K., Cronin A., Davis P., Fraser A., Hance Z.,
RA   Hauser H., Jagels K., Moule S., Mungall K., Norbertczak H.,
RA   Rabbinowitsch E., Sanders M., Simmonds M., Whitehead S., Parkhill J.;
RT   "The genome of Rhizobium leguminosarum has recognizable core and accessory
RT   components.";
RL   Genome Biol. 7:R34.1-R34.20(2006).
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DR   EMBL; AM236080; CAK08759.1; -; Genomic_DNA.
DR   RefSeq; WP_011652768.1; NC_008380.1.
DR   AlphaFoldDB; Q1ME67; -.
DR   EnsemblBacteria; CAK08759; CAK08759; RL3271.
DR   KEGG; rle:RL3271; -.
DR   eggNOG; COG2114; Bacteria.
DR   HOGENOM; CLU_924011_0_0_5; -.
DR   Proteomes; UP000006575; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000313|EMBL:CAK08759.1}; Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius, ECO:0000313|EMBL:CAK08759.1};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        212..229
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        235..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        264..281
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        287..304
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          10..124
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
FT   REGION          176..199
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   306 AA;  32963 MW;  5AB22E3FB9E8C4FB CRC64;
     MSETRRKLTT IFCADVQDYT RLMGADEEGT LAALKRCREA MGRLIESHGG RVINTWGDGL
     IADFPSVVEA VRAAVDTQNE LAGFNARRPA DGRMLFRIGI NLGDVIVEGD DIYGDGVNIA
     ARLQTSAAAG GIVISSTVYD QVRNKVAVGF EFLGPLMVKN VDEGVPSYAV KIGDARDETP
     SAERSGPARP QPAPVMAAAE AETTPAPGGR RLYGVLGVIA AVLIGINLLS WQGVFWARFP
     VLALAVIAAL AWNRDQIRFN RKITLLAILA LGLAGINLFT WTGQFWAVWP ILGIAAVMGV
     RWSMRR
//