ID   ADEC1_RHIL3             Reviewed;         569 AA.
AC   Q1MDE8;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2006, sequence version 1.
DT   16-JUN-2009, entry version 19.
DE   RecName: Full=Adenine deaminase 1;
DE            Short=Adenase 1;
DE            Short=Adenine aminase 1;
DE            EC=3.5.4.2;
GN   Name=ade1; OrderedLocusNames=RL3541;
OS   Rhizobium leguminosarum bv. viciae (strain 3841).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=216596;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16640791; DOI=10.1186/gb-2006-7-4-r34;
RA   Young J.P.W., Crossman L.C., Johnston A.W.B., Thomson N.R.,
RA   Ghazoui Z.F., Hull K.H., Wexler M., Curson A.R.J., Todd J.D.,
RA   Poole P.S., Mauchline T.H., East A.K., Quail M.A., Churcher C.,
RA   Arrowsmith C., Cherevach I., Chillingworth T., Clarke K., Cronin A.,
RA   Davis P., Fraser A., Hance Z., Hauser H., Jagels K., Moule S.,
RA   Mungall K., Norbertczak H., Rabbinowitsch E., Sanders M., Simmonds M.,
RA   Whitehead S., Parkhill J.;
RT   "The genome of Rhizobium leguminosarum has recognizable core and
RT   accessory components.";
RL   Genome Biol. 7:RESEARCH34.1-RESEARCH34.20(2006).
CC   -!- CATALYTIC ACTIVITY: Adenine + H(2)O = hypoxanthine + NH(3).
CC   -!- COFACTOR: Manganese (By similarity).
CC   -!- SIMILARITY: Belongs to the adenine deaminase family.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AM236080; CAK09029.1; -; Genomic_DNA.
DR   RefSeq; YP_769121.1; -.
DR   GeneID; 4401837; -.
DR   GenomeReviews; AM236080_GR; RL3541.
DR   KEGG; rle:RL3541; -.
DR   NMPDR; fig|216596.1.peg.3658; -.
DR   HOGENOM; Q1MDE8; -.
DR   OMA; Q1MDE8; PGKIITE.
DR   GO; GO:0000034; F:adenine deaminase activity; IEA:HAMAP.
DR   GO; GO:0030145; F:manganese ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006146; P:adenine catabolic process; IEA:InterPro.
DR   HAMAP; MF_01518; -; 1.
DR   InterPro; IPR006679; Adenine_deam.
DR   InterPro; IPR006680; Amidohydro_1.
DR   Pfam; PF01979; Amidohydro_1; 1.
DR   TIGRFAMs; TIGR01178; ade; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase; Manganese.
FT   CHAIN         1    569       Adenine deaminase 1.
FT                                /FTId=PRO_0000292394.
SQ   SEQUENCE   569 AA;  61076 MW;  7078051D6BA25993 CRC64;
     MSNAMTSKLE RFIDQGVGRV PADIVLKGGC FFDLVTGELV QSDIAIGADR IVGTSGNYEG
     ETEIDISGRI VVPGFIDTHL HIESSLVTPH EFDRCVLPYG VTTAICDPHE IANVLGAAGI
     EFFLESALET IMDIRVQLSS CVPATHLETS GADLPIESLL PYRHHPKVIG LAEFMNFPGV
     IHKDPICMAK LDAFQGGHID GHAPLLSGND LNGYLAAGIR TEHECTTASE ALEKIRKGVH
     ILVREGSVSK DLAALMPIIT ERLSPFLALC TDDRNPLDIA EQGHLDHMIR TAIASRVEPL
     AIYRAASISA ARAFGLKDRG LVAPGWRADL VVLDSLENCR ADMVFSAGRR VTDALFSSRR
     PVAPIGLDSV KARPVNAAHF GVPVAEGETP VIGVIPGKII TEHRRYRLPV RGNEAAVDLA
     NDIIKVAVIE RHGKNGNHAN GFVQGFGLKK GAIASTVGHD SHNICVVGVS EDDMARAANR
     LSEIKGGFVV VEDGKVTGEI ALPIAGLMSL EPYETVRDTL HQLRKAAFAL GATLEEPFLQ
     LAFLPLPVIP HLKISDRGMV DVDKFALIG
//