Q1MCV4 (URED_RHIL3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Urease accessory protein UreD

Gene names

Name:	ureD
Ordered Locus Names:	RL3736

Organism

Rhizobium leguminosarum bv. viciae (strain 3841) [Complete proteome] [HAMAP]

Taxonomic identifier

216596 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Rhizobium

Protein attributes

Sequence length	273 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter By similarity. HAMAP MF_01384
Subunit structure	UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel By similarity.
Subcellular location	Cytoplasm By similarity HAMAP MF_01384.
Sequence similarities	Belongs to the UreD family.

Ontologies

Keywords
Biological process	Nickel insertion
Cellular component	Cytoplasm
Molecular function	Chaperone
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nickel cation binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 273	273	Urease accessory protein UreD HAMAP MF_01384		PRO_0000340503

Sequences

	Sequence		Length	Mass (Da)
	Q1MCV4 [UniParc]. Last modified May 30, 2006. Version 1. Checksum: 581FE000DD154237	FASTA	273	29,261
	10 20 30 40 50 60 MTIAAAGTRP QRAEGRGHLA AKLFDGRTRI RELYQEGAAK IRLPDTFDAS MEAVIINTAG 70 80 90 100 110 120 GLTGGDRMDW SVDAGPGTRI DVTTQACEKI YKASAGIAEV ATSIKVGAQA RVDWLPQETI 130 140 150 160 170 180 LFDRAALFRR LDVDLDESAE FLAVEAVLLG RKAMGEAVVS GLFRDRWRIR RSGQLIHAEE 190 200 210 220 230 240 LRLSEGVAAL AARQAVLGGQ VAFATLLYAG PLLEAYLSKV RPLVEGSMGG ASAWNGKLVV 250 260 270 RLAAADGFSL RKILIPVISA LRNGAPVPKV WNL

References

[1]

"The genome of Rhizobium leguminosarum has recognizable core and accessory components." Young J.P.W., Crossman L.C., Johnston A.W.B., Thomson N.R., Ghazoui Z.F., Hull K.H., Wexler M., Curson A.R.J., Todd J.D., Poole P.S., Mauchline T.H., East A.K., Quail M.A., Churcher C., Arrowsmith C., Cherevach I., Chillingworth T., Clarke K. , Cronin A., Davis P., Fraser A., Hance Z., Hauser H., Jagels K., Moule S., Mungall K., Norbertczak H., Rabbinowitsch E., Sanders M., Simmonds M., Whitehead S., Parkhill J. Genome Biol. 7:R34.1-R34.20(2006) [PubMed: 16640791] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 3841.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM236080 Genomic DNA. Translation: CAK09226.1.
RefSeq	YP_769315.1. NC_008380.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q1MCV4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4403130.
GenomeReviews	Gene locus RL3736 in contig AM236080_GR.
KEGG	rle:RL3736.
NMPDR	fig|216596.1.peg.3861.
PATRIC	23144259. VBIRhiLeg32091_5048.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0829.
HOGENOM	HBG711156.
OMA	QETILFD.
ProtClustDB	CLSK2487147.
Enzyme and pathway databases
BioCyc	RLEG216596:RL3736-MONOMER.
Family and domain databases
HAMAP	MF_01384. UreD. [Tree]
InterPro	IPR002669. UreD. [Graphical view]
KO	K03190.
Pfam	PF01774. UreD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

URED_RHIL3

Accession

Primary (citable) accession number: Q1MCV4

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	May 30, 2006
Last modified:	January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program