Reviewed, UniProtKB/Swiss-Prot Q1MCF8 (ADEC2_RHIL3)

Names and origin

Protein names

Recommended name:
    Adenine deaminase 2
      Short name=Adenase 2
      Short name=Adenine aminase 2
    EC=3.5.4.2

Gene names

Name:	ade2
Ordered Locus Names:	RL3883

Organism

Rhizobium leguminosarum bv. viciae (strain 3841) [Complete proteome] [HAMAP]

Taxonomic identifier

216596 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Rhizobium

Protein attributes

Sequence length	595 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Adenine + H2O = hypoxanthine + NH3. HAMAP MF_01518
Cofactor	Manganese By similarity.
Sequence similarities	Belongs to the adenine deaminase family.

Ontologies

Keywords
Ligand	Manganese
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	adenine deaminase activity Inferred from electronic annotation. Source: HAMAP manganese ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 595	595	Adenine deaminase 2 HAMAP MF_01518		PRO_0000292395

Sequences

	Sequence		Length	Mass (Da)
	Q1MCF8-1 [UniParc]. Last modified May 30, 2006. Version 1. Checksum: 54D0D1C8F6DC3D5B	FASTA	595	62,817
	10 20 30 40 50 60 MNATARQEPA DLNDPALRAR AVTAARGDAP FDMLITGGRL LDTVTGLIRQ ADIGLVGALI 70 80 90 100 110 120 SSVHAPASRT DAVEIIDAAG SILTPGLIDT HMHIESSMVT PAEYASAVLP RGVTTIVWDP 130 140 150 160 170 180 HEFGNVHGLD GVRWAIEAAR SLPLRMILLA PSCVPSAPGL ELAGADFDAS MITEMLHSSA 190 200 210 220 230 240 VGGVAEVMNM RGVIDGDPRM TDIVNAGLAA GKLVCGHARG LEGADLNAFM ASGITSDHEL 250 260 270 280 290 300 TSGADLLAKL SAGLTIELRG SHDHLLQEFV EVLSGLGHLP PTVTLCTDDV FPDELQEGGG 310 320 330 340 350 360 LDDVVRRLVR YGMKPEWAIR AATFNAAQRL KRSDLGLVAT GRRADIVLFE DLTEFRARLV 370 380 390 400 410 420 ISGGRIVARN GSMQVAVQQI DTAPLVNSVK LPPLTENDFR IPAKGERVRV ATIDRPRFTQ 430 440 450 460 470 480 WGEAETEVRD GFIVPPAGSA MISVAHRHGK TDGIPRIGFL TGWGEWRGAF CTTVSHDSHN 490 500 510 520 530 540 LTVFGGNAGD MALAANAVIS AGGGMAVAKD GRIEAMLPLP LSGLVTDASL KDTALAFAGI 550 560 570 580 590 RKAMEKIVTW KPPYLVFKAC FGATLACNVG PHQTDQGIAD VVTGKVLENP VLAVW

References

[1]

"The genome of Rhizobium leguminosarum has recognizable core and accessory components." Young J.P.W., Crossman L.C., Johnston A.W.B., Thomson N.R., Ghazoui Z.F., Hull K.H., Wexler M., Curson A.R.J., Todd J.D., Poole P.S., Mauchline T.H., East A.K., Quail M.A., Churcher C., Arrowsmith C., Cherevach I., Chillingworth T., Clarke K. , Cronin A., Davis P., Fraser A., Hance Z., Hauser H., Jagels K., Moule S., Mungall K., Norbertczak H., Rabbinowitsch E., Sanders M., Simmonds M., Whitehead S., Parkhill J. Genome Biol. 7:RESEARCH34.1-RESEARCH34.20(2006) [PubMed: 16640791] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AM236080 Genomic DNA. Translation: CAK09373.1.
RefSeq	YP_769461.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4401838.
GenomeReviews	Gene locus RL3883 in contig AM236080_GR.
KEGG	rle:RL3883.
NMPDR	fig|216596.1.peg.4009.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q1MCF8.
OMA	Q1MCF8. LACNAGP.
Family and domain databases
HAMAP	MF_01518. [Tree]
InterPro	IPR006680. Amidohydro_1. [Graphical view]
Pfam	PF01979. Amidohydro_1. 1 hit. [Graphical view]
ProDom	PD001248. Amidohydro_like. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

ADEC2_RHIL3

Accession

Primary (citable) accession number: Q1MCF8

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 26, 2007
Last sequence update:	May 30, 2006
Last modified:	May 5, 2009
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)